Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Pagliarello C and Paradisi A | Topical tacrolimus is useful for avoiding suction-blister epidermal grafting depigmentation in non-segmental vitiligo: a case report. | 2012 | Acta Derm. Venereol. | pmid:22101735 |
Hamade Y et al. | Lichen planus in childhood showing various cutaneous features. | 2012 | Acta Derm. Venereol. | pmid:22101991 |
Mandelin J et al. | Leg ulcers treated with topical tacrolimus in patients with rheumatoid arthritis. | 2010 | Acta Derm. Venereol. | pmid:21057750 |
Nakamizo S et al. | Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin. | 2010 | Acta Derm. Venereol. | pmid:21057761 |
Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
Pagliarello C et al. | Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more. | 2012 | Acta Derm. Venereol. | pmid:22293917 |
Schreier MH | Immunophilins and immunosuppression by cyclosporins and macrolide structures. | 1994 | Acta Derm Venereol Suppl (Stockh) | pmid:7521103 |
Liang J et al. | Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution. | 1999 | Acta Crystallogr. D Biol. Crystallogr. | pmid:10089303 |
Bracher A et al. | Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90. | 2011 | Acta Crystallogr. D Biol. Crystallogr. | pmid:21636895 |
Li P et al. | Structure of the N-terminal domain of human FKBP52. | 2003 | Acta Crystallogr. D Biol. Crystallogr. | pmid:12499534 |
Waer M | New immunosuppressive agents for organ transplantation. | 1997 | Acta Clin Belg | pmid:9351290 |
Morello RJ et al. | Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice. | 2016 | Acta Cir Bras | pmid:27828601 |
Cavalli RC et al. | Analysis of the histology of the scar bladder and biochemical parameters of rats with a solitary kidney undergoing immunosuppression with tacrolimus. | 2014 | Acta Cir Bras | pmid:25140592 |
Inácio CM et al. | Action of tacrolimus on Wistar rat kidneys implanted with Walker 256 carcinosarcoma. | 2010 | Acta Cir Bras | pmid:20126896 |
Dias PH et al. | Effects of immunosuppression with tacrolimus and mycophenolate mofetil on renal histology and function in single kidney rats submitted to ischemia and reperfusion. | 2015 | Acta Cir Bras | pmid:25714692 |
Ricciardi S et al. | Infections and immunosuppression as specific problems in a HIV + patient transplanted for end-stage alcoholic cirrhosis. | 2007 Mar-Apr | Acta Chir. Belg. | pmid:17515275 |
Vermeulen T et al. | Severe stomatitis complicating immune-suppressive switch after cardiac transplantation. | 2010 May-Jun | Acta Chir. Belg. | pmid:20690519 |
Frantzeskaki F et al. | Posterior reversible encephalopathy syndrome in an intensive care unit patient receiving tacrolimus. | 2008 | Acta Anaesthesiol Scand | pmid:18840131 |
Lechner A et al. | Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering. | 2013 | ACS Synth Biol | pmid:23654255 |
Butler KV et al. | Targeted Gene Repression Using Novel Bifunctional Molecules to Harness Endogenous Histone Deacetylation Activity. | 2018 | ACS Synth Biol | pmid:29073761 |