| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mycobacterium Infections | D009164 | 7 associated lipids |
| Sarcoidosis | D012507 | 13 associated lipids |
| Hepatolenticular Degeneration | D006527 | 3 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wong KM et al. | Tacrolimus versus cyclosporine as primary prophylactic therapy after cadaveric renal transplant: two-year survival study. | 2000 | Transplant. Proc. | pmid:11119907 |
| Tanabe K et al. | Malabsorption of tacrolimus in kidney transplant recipients: a Japanese single center experience. | 2000 | Transplant. Proc. | pmid:11119906 |
| Okamoto M et al. | Beneficial effect of multiple drug therapy including tacrolimus in clinical renal transplantation. | 2000 | Transplant. Proc. | pmid:11119905 |
| Jang HJ et al. | Conversion from cyclosporine to tacrolimus in renal allograft recipients with delayed graft function from severe acute tubular necrosis. | 2000 | Transplant. Proc. | pmid:11119904 |
| Tanabe K et al. | ABO-incompatible living donor kidney transplantation under tacrolimus immunosuppression. | 2000 | Transplant. Proc. | pmid:11119903 |
| Yu L et al. | Clinical experience with Prograf (tacrolimus, FK 506) in Chinese patients after renal transplantation. | 2000 | Transplant. Proc. | pmid:11119902 |
| Park K et al. | Efficacy of tacrolimus in primary kidney transplant patients: multicenter, open-label prospective study. | 2000 | Transplant. Proc. | pmid:11119901 |
| Youhua Z et al. | Clinical study of FK 506 in renal transplant recipients. | 2000 | Transplant. Proc. | pmid:11119900 |
| Wang XH et al. | Tacrolimus vs CyA Neoral in combination with MMF and steroids after cadaveric renal transplantation. | 2000 | Transplant. Proc. | pmid:11119899 |
| Lye WC | Primary tacrolimus-based immunosuppression in renal allograft recipients: a single center experience. | 2000 | Transplant. Proc. | pmid:11119898 |
| Tanabe K et al. | Japanese single-center experience of kidney transplantation under tacrolimus immunosuppression. | 2000 | Transplant. Proc. | pmid:11119897 |
| Yuan QS et al. | Rescue therapy with tacrolimus in renal graft patients with cyclosporine A-induced hepatotoxicity: a preliminary study. | 2000 | Transplant. Proc. | pmid:11119896 |
| Yashima J et al. | Successful conversion from tacrolimus to cyclosporine after kidney transplantation. | 2000 | Transplant. Proc. | pmid:11119895 |
| Hu RH et al. | Clinical influencing factors for daily dose, trough level, and relative clearance of tacrolimus in renal transplant recipients. | 2000 | Transplant. Proc. | pmid:11119894 |
| Braun F et al. | Primary tacrolimus immunosuppression in kidney recipients considered "higher immunological risk". | 2000 | Transplant. Proc. | pmid:11119893 |
| Uchida K et al. | Preventive effect of FK 506 (tacrolimus hydrate) on experimentally induced acute liver injury in rats. | 2000 | Dig. Dis. Sci. | pmid:11117573 |
| Petty EM et al. | Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia. | 2000 | J. Pediatr. | pmid:11113849 |
| Bousvaros A et al. | Oral tacrolimus treatment of severe colitis in children. | 2000 | J. Pediatr. | pmid:11113835 |
| von Steinbüchel N et al. | Assessment of health-related quality-of-life in patients after heart transplantation under therapy with tacrolimus or cyclosporine. | 2000 | Transpl. Int. | pmid:11112084 |
| Timmermann W et al. | Long-term small bowel allograft function induced by short-term FK 506 application is associated with split tolerance. | 2000 | Transpl. Int. | pmid:11112067 |
| Kohnle M et al. | Conversion from cyclosporine A to tacrolimus after kidney transplantation due to hyperlipidemia. | 2000 | Transpl. Int. | pmid:11112029 |
| Spada M et al. | Rejection and tacrolimus conversion therapy in paediatric liver transplantation. | 2000 | Transpl. Int. | pmid:11112028 |
| Segoloni G et al. | Tacrolimus is highly effective in both dual and triple therapy regimens following renal transplantation. Spanish and Italian Tacrolimus Study Group. | 2000 | Transpl. Int. | pmid:11112027 |
| Kainz A et al. | Analysis of 100 pregnancy outcomes in women treated systemically with tacrolimus. | 2000 | Transpl. Int. | pmid:11112018 |
| Mohamed MA et al. | Active TGF-beta1 expression in kidney transplantation: a comparative study of cyclosporin-A (CyA) and tacrolimus (FK506). | 2000 | Transpl. Int. | pmid:11112017 |
| Steurer W et al. | Incidence of intraabdominal infection in a consecutive series of 40 enteric-drained pancreas transplants with FK506 and MMF immunosuppression. | 2000 | Transpl. Int. | pmid:11111995 |
| Ciancio G et al. | Use of tacrolimus and mycophenolate mofetil as induction and maintenance in simultaneous pancreas-kidney transplantation. | 2000 | Transpl. Int. | pmid:11111994 |
| Platz KP et al. | Liver transplantation for alcoholic cirrhosis. | 2000 | Transpl. Int. | pmid:11111978 |
| Meyer D et al. | "Tolerogenic effect" of the liver for a small bowel allograft. | 2000 | Transpl. Int. | pmid:11111977 |
| Toki K et al. | Clinicopathological evaluation in non-episode biopsies of renal transplant allograft. | 2000 | Transpl. Int. | pmid:11111966 |
| Jain S et al. | Sub-clinical acute rejection detected using protocol biopsies in patients with delayed graft function. | 2000 | Transpl. Int. | pmid:11111961 |
| pmid:11111152 | ||||
| Fatkin D et al. | An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy. | 2000 | J. Clin. Invest. | pmid:11104788 |
| Taniguchi T et al. | Phosphorylation of tau is regulated by PKN. | 2001 | J. Biol. Chem. | pmid:11104762 |
| Fong CW et al. | Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner. | 2000 | Biochem. J. | pmid:11104682 |
| Mori A et al. | Fatal cerebral hemorrhage associated with cyclosporin-A/FK506-related encephalopathy after allogeneic bone marrow transplantation. | 2000 | Ann. Hematol. | pmid:11100753 |
| Furlong T et al. | Clinical outcome after conversion to FK 506 (tacrolimus) therapy for acute graft-versus-host disease resistant to cyclosporine or for cyclosporine-associated toxicities. | 2000 | Bone Marrow Transplant. | pmid:11100278 |
| Vidal E et al. | Mycophenolate mofetil pharmacokinetics in transplant patients receiving cyclosporine or tacrolimus in combination therapy. | 2000 | Pharmacol. Toxicol. | pmid:11097273 |
| Lübbe J et al. | Eczema herpeticum during treatment of atopic dermatitis with 0.1% tacrolimus ointment. | 2000 | Dermatology (Basel) | pmid:11096198 |
| Satchell S et al. | Pregnancy, tacrolimus, and renal transplantation: survival of a 358-g baby. | 2000 | Nephrol. Dial. Transplant. | pmid:11096162 |
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| Zabawski EJ et al. | Tacrolimus: pharmacology and therapeutic uses in dermatology. | 2000 | Int. J. Dermatol. | pmid:11095187 |
| Myers SA | Update on new immunomodulatory agents. | 2000 | Adv Dermatol | pmid:11094629 |
| Ambach A et al. | The serine phosphatases PP1 and PP2A associate with and activate the actin-binding protein cofilin in human T lymphocytes. | 2000 | Eur. J. Immunol. | pmid:11093160 |
| Watanabe S et al. | A peculiar vacuolization in the kidney transplant of a child treated with tacrolimus. | 2000 | Clin Transplant | pmid:11092350 |
| Toki K et al. | Arteriolopathy in non-episode biopsies of renal transplant allograft. | 2000 | Clin Transplant | pmid:11092348 |
| Bicknell GR et al. | Differential effects of cyclosporin and tacrolimus on the expression of fibrosis-associated genes in isolated glomeruli from renal transplants. | 2000 | Br J Surg | pmid:11091247 |
| Jain S et al. | Tacrolimus has less fibrogenic potential than cyclosporin A in a model of renal ischaemia-reperfusion injury. | 2000 | Br J Surg | pmid:11091246 |
| Jain A et al. | Long-term follow-up after liver transplantation for alcoholic liver disease under tacrolimus. | 2000 | Transplantation | pmid:11087149 |
| Shi J et al. | Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents. | 2000 | Neuron | pmid:11086987 |
| Chang GJ et al. | Experience with the use of sirolimus in liver transplantation--use in patients for whom calcineurin inhibitors are contraindicated. | 2000 | Liver Transpl. | pmid:11084060 |
| Bathgate AJ et al. | Pretransplantation tumor necrosis factor-alpha production predicts acute rejection after liver transplantation. | 2000 | Liver Transpl. | pmid:11084058 |
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| Shimizu K et al. | Tacrolimus (FK506) treatment of CD34+ hematopoietic progenitor cells promote the development of dendritic cells that drive CD4+ T cells toward Th2 responses. | 2000 | J. Leukoc. Biol. | pmid:11073101 |
| Dale S and Shaw J | Clinical picture. Eosinophilic pustular folliculitis. | 2000 | Lancet | pmid:11072943 |
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| Bova D et al. | Delayed transient neurologic toxicity due to tacrolimus: CT and MRI. | 2000 | Neuroradiology | pmid:11071440 |
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| Jiang H et al. | Distinct patterns of cytokine gene suppression by the equivalent effective doses of cyclosporine and tacrolimus in rat heart allografts. | 2000 | Immunobiology | pmid:11045663 |
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| Przepiorka D et al. | Tacrolimus clearance is age-dependent within the pediatric population. | 2000 | Bone Marrow Transplant. | pmid:11041564 |
| Nakahama H et al. | Co-administration of furosemide augments tacrolimus-induced impairment in kidney function in rats. | 2000 | Ren Fail | pmid:11041285 |
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| van Gelder T et al. | Drug interaction between mycophenolate mofetil and tacrolimus detectable within therapeutic mycophenolic acid monitoring in renal transplant patients. | 2000 | Ther Drug Monit | pmid:11034275 |
| Taylor PJ et al. | Simultaneous quantification of tacrolimus and sirolimus, in human blood, by high-performance liquid chromatography-tandem mass spectrometry. | 2000 | Ther Drug Monit | pmid:11034268 |
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| Marsen TA et al. | Differential transcriptional regulation of endothelin-1 by immunosuppressants FK506 and cyclosporin A. | 2000 Jul-Aug | Fundam Clin Pharmacol | pmid:11030448 |
| Matsuura M et al. | Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats. | 2000 | Inflamm. Res. | pmid:11028757 |
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| Bronster DJ et al. | Tacrolimus-associated mutism after orthotopic liver transplantation. | 2000 | Transplantation | pmid:11014653 |
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