| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mycobacterium Infections | D009164 | 7 associated lipids |
| Sarcoidosis | D012507 | 13 associated lipids |
| Hepatolenticular Degeneration | D006527 | 3 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Reyes J et al. | Long-term results after conversion from cyclosporine to tacrolimus in pediatric liver transplantation for acute and chronic rejection. | 2000 | Transplantation | pmid:10910279 |
| MacDonald AS | Management strategies for nephrotoxicity. | 2000 | Transplantation | pmid:10910262 |
| Fisher NC et al. | The clinical impact of nephrotoxicity in liver transplantation. | 2000 | Transplantation | pmid:10910259 |
| Wang L et al. | Reversal of anticancer drug resistance by macrolide antibiotics in vitro and in vivo. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10901387 |
| Hishinuma S and Ogura K | Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells. | 2000 | J. Neurochem. | pmid:10899954 |
| Mukerjee N et al. | Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells. | 2000 | Arch. Biochem. Biophys. | pmid:10898953 |
| Yue G et al. | The effect of rapamycin on single ENaC channel activity and phosphorylation in A6 cells. | 2000 | Am. J. Physiol., Cell Physiol. | pmid:10898719 |
| Mori A et al. | Control of IL-5 production by human helper T cells as a treatment for eosinophilic inflammation: comparison of in vitro and in vivo effects between selective and nonselective cytokine synthesis inhibitors. | 2000 | J. Allergy Clin. Immunol. | pmid:10887335 |
| Hooijberg E et al. | NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells. | 2000 | Blood | pmid:10887106 |
| Arthur JM and Shamim S | Interaction of cyclosporine and FK506 with diuretics in transplant patients. | 2000 | Kidney Int. | pmid:10886578 |
| Zaman AK | Effects of tacrolimus hydrate (FK-506) on the expression of tissue factor in THP-1 human monocyte cell line. | 2000 | Hokkaido Igaku Zasshi | pmid:10884973 |
| Terashima A et al. | Rapamycin and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca(2+) signaling mechanism in rat hippocampal CA1 neurons. | 2000 | Neuropharmacology | pmid:10884573 |
| Parker EM et al. | Rapamycin, but not FK506 and GPI-1046, increases neurite outgrowth in PC12 cells by inhibiting cell cycle progression. | 2000 | Neuropharmacology | pmid:10884572 |
| Romano G et al. | Systemic and intratubular effects of cyclosporin-A and tacrolimus on the rat kidney. | 2000 | Eur. J. Pharmacol. | pmid:10884522 |
| Ben Abraham R et al. | [FK506 (tacrolimus) does not increase hepatic damage due to hypoperfusion]. | 2000 | Harefuah | pmid:10883243 |
| Hamazaki T et al. | [Prophylaxis with FK-506 for graft-versus-host disease after transplantation of bone marrow from unrelated donors]. | 2000 | Rinsho Ketsueki | pmid:10879106 |
| Assmann T et al. | Applications of tacrolimus for the treatment of skin disorders. | 2000 | Immunopharmacology | pmid:10878290 |
| Allison AC | Immunosuppressive drugs: the first 50 years and a glance forward. | 2000 | Immunopharmacology | pmid:10878284 |
| Castilho RF et al. | FK506 and cyclosporin A enhance the survival of cultured and grafted rat embryonic dopamine neurons. | 2000 | Exp. Neurol. | pmid:10877919 |
| Costantini LC and Isacson O | Immunophilin ligands and GDNF enhance neurite branching or elongation from developing dopamine neurons in culture. | 2000 | Exp. Neurol. | pmid:10877916 |
| Morales JM et al. | Immunosuppression in older renal transplant patients. | 2000 | Drugs Aging | pmid:10874523 |
| Queille-Roussel C et al. | SDZ ASM 981 is the first non-steroid that suppresses established nickel contact dermatitis elicited by allergen challenge. | 2000 | Contact Derm. | pmid:10871099 |
| Au WY et al. | Tacrolimus (FK 506) induced thrombotic thrombocytopenic purpura after ABO mismatched second liver transplantation: salvage with plasmapheresis and prostacyclin. | 2000 | Haematologica | pmid:10870125 |
| Neuhaus P et al. | Quadruple tacrolimus-based induction therapy including azathioprine and ALG does not significantly improve outcome after liver transplantation when compared with standard induction with tacrolimus and steroids: results of a prospective, randomized trial. | 2000 | Transplantation | pmid:10868638 |
| Blakolmer K et al. | Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging. | 2000 | Transplantation | pmid:10868635 |
| Yamani MH et al. | The impact of routine mycophenolate mofetil drug monitoring on the treatment of cardiac allograft rejection. | 2000 | Transplantation | pmid:10868634 |
| Oike F et al. | A 12-day course of FK506 allows long-term acceptance of semi-identical liver allograft in inbred miniature swine. | 2000 | Transplantation | pmid:10868630 |
| Wu K et al. | The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units. | 2000 | Gene | pmid:10863099 |
| Boubenider S et al. | Interaction between theophylline and tacrolimus in a renal transplant patient. | 2000 | Nephrol. Dial. Transplant. | pmid:10862651 |
| Morelli AE et al. | Microchimerism, donor dendritic cells, and alloimmune reactivity in recipients of Flt3 ligand-mobilized hemopoietic cells: modulation by tacrolimus. | 2000 | J. Immunol. | pmid:10861056 |
| McLaughlin GE et al. | Effect of aminophylline on urine flow in children with tacrolimus-induced renal insufficiency. | 2000 | Transplant. Proc. | pmid:10856596 |
| Malinowski K et al. | Effect of different anti-rejection regimens on the expression of differentiation and activation markers on the surface of host lymphocytes. | 2000 | Transplant. Proc. | pmid:10856579 |
| Gotsman I et al. | Effect of peripheral immune tolerance on liver-associated lymphocytes expressing NK1.1. | 2000 | Transplant. Proc. | pmid:10856569 |
| Barak S et al. | Alveolar bone height in patients after liver transplantation. | 2000 | Transplant. Proc. | pmid:10856558 |
| Ben-Ari Z et al. | Conversion of liver allograft recipients from cyclosporine A to FK 506 immunosuppressive therapy. | 2000 | Transplant. Proc. | pmid:10856553 |
| Granot E et al. | Monitoring of Epstein-Barr virus serology in children after liver transplant: lack of clinical correlation. | 2000 | Transplant. Proc. | pmid:10856551 |
| Bultynck G et al. | Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms. | 2000 | J. Physiol. (Lond.) | pmid:10856121 |
| Kochi S et al. | Induction of apoptosis in mouse brain capillary endothelial cells by cyclosporin A and tacrolimus. | 2000 | Life Sci. | pmid:10855946 |
| Florio G et al. | The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils. | 2000 | AIDS | pmid:10853974 |
| Rollins CT et al. | A ligand-reversible dimerization system for controlling protein-protein interactions. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10852943 |
| Schvarcz R et al. | Interaction between nelfinavir and tacrolimus after orthoptic liver transplantation in a patient coinfected with HIV and hepatitis C virus (HCV). | 2000 | Transplantation | pmid:10852623 |
| Konrad T et al. | Regulation of glucose tolerance in patients after liver transplantation: impact of cyclosporin versus tacrolimus therapy. | 2000 | Transplantation | pmid:10852599 |
| Gibson SW et al. | Nutritional immunomodulation leads to enhanced allograft survival in combination with cyclosporine A and rapamycin, but not FK506. | 2000 | Transplantation | pmid:10852592 |
| Tyedmers J et al. | Assembly of heterodimeric luciferase after de novo synthesis of subunits in rabbit reticulocyte lysate involves hsc70 and hsp40 at a post-translational stage. | 2000 | Eur. J. Biochem. | pmid:10848974 |
| Small bowel transplants in adults and multivisceral transplants in adults and children. | 1999 | Tecnologica MAP Suppl | pmid:10848042 | |
| Zhang F et al. | Resistance to Friend murine leukemia virus infection conferred by the Fv-4 gene is recessive but appears dominant from the effect of the immune system. | 2000 | J. Virol. | pmid:10846105 |
| Samsonov D et al. | Enhancement of immune tolerance via induction of NK1.1 positive liver-associated-lymphocytes under immunosuppressive conditions. | 2000 | J. Hepatol. | pmid:10845669 |
| Nasr IS | Topical tacrolimus in dermatology. | 2000 | Clin. Exp. Dermatol. | pmid:10844509 |
| Rabinowitz M et al. | Solid-phase/solution-phase combinatorial synthesis of neuroimmunophilin ligands. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10843203 |
| Yoshikawa T et al. | In vivo osteogenic capability of cultured allogeneic bone in porous hydroxyapatite: immunosuppressive and osteogenic potential of FK506 in vivo. | 2000 | J. Bone Miner. Res. | pmid:10841184 |
| Oberholzer J et al. | Daclizumab as escape therapy for late acute kidney rejection in the presence of FK506 nephrotoxicity. | 2000 | Transpl. Int. | pmid:10836657 |
| Higgins RM et al. | Conversion from tacrolimus to cyclosporine in stable renal transplant patients: safety, metabolic changes, and pharmacokinetic comparison. | 2000 | Transplantation | pmid:10836393 |
| Moffatt SD and Metcalfe SM | Comparison between tacrolimus and cyclosporine as immunosuppressive agents compatible with tolerance induction by CD4/CD8 blockade. | 2000 | Transplantation | pmid:10836388 |
| Chen H et al. | Compromised kidney graft rejection response in Vervet monkeys after withdrawal of immunosuppressants tacrolimus and sirolimus. | 2000 | Transplantation | pmid:10836361 |
| Gallagher H et al. | Post-transplantation lymphoproliferative disorder: an unusual presentation in a patient receiving tacrolimus. | 2000 | Nephrol. Dial. Transplant. | pmid:10831670 |
| Filler G et al. | Tacrolimus reversibly reduces insulin secretion in paediatric renal transplant recipients. | 2000 | Nephrol. Dial. Transplant. | pmid:10831643 |
| Rerolle JP et al. | Tacrolimus-induced hemolytic uremic syndrome and end-stage renal failure after liver transplantation. | 2000 | Clin Transplant | pmid:10831087 |
| Jindal RM and Dubernard JM | Towards a specific immunosuppression for pancreas and islet grafts. | 2000 | Clin Transplant | pmid:10831083 |
| Blaheta RA et al. | Mycophenolate mofetil decreases endothelial prostaglandin E2 in response to allogeneic T cells or cytokines. | 2000 | Transplantation | pmid:10830246 |
| Nakata Y et al. | Tacrolimus and myocardial hypertrophy. | 2000 | Transplantation | pmid:10830241 |
| Eckhoff DE et al. | The safety and efficacy of a two-dose daclizumab (zenapax) induction therapy in liver transplant recipients. | 2000 | Transplantation | pmid:10830224 |
| Otley CC and Pittelkow MR | Skin cancer in liver transplant recipients. | 2000 | Liver Transpl. | pmid:10827224 |
| Bang H et al. | Prolyl isomerases in a minimal cell. Catalysis of protein folding by trigger factor from Mycoplasma genitalium. | 2000 | Eur. J. Biochem. | pmid:10824113 |
| Ortega-Pérez I and Redondo JM | [The NFAT transcription factor family as immunosuppression target]. | 2000 | Nefrologia | pmid:10822734 |
| Wang JJ et al. | Dimerization-dependent block of the proapoptotic effect of p75(NTR). | 2000 | J. Neurosci. Res. | pmid:10820429 |
| Küsters E et al. | Purification of an ascomycin derivative with simulated moving bed chromatography. A case study. | 2000 | J Chromatogr A | pmid:10817355 |
| Przepiorka D et al. | Tacrolimus does not abrogate the increased risk of acute graft-versus-host disease after unrelated-donor marrow transplantation with allelic mismatching at HLA-DRB1 and HLA-DQB1. | 2000 | Biol. Blood Marrow Transplant. | pmid:10816027 |
| Levy GA | Neoral use in the liver transplant recipient. | 2000 | Transplant. Proc. | pmid:10814745 |
| McLaughlin GE et al. | Use of phenobarbital in the management of acute tacrolimus toxicity: a case report. | 2000 | Transplant. Proc. | pmid:10812158 |
| Soran A et al. | Renal retransplantation in elderly recipients under tacrolimus-based immunosuppression. | 2000 | Transplant. Proc. | pmid:10812157 |
| Taber DJ et al. | Drug-drug interaction between chloramphenicol and tacrolimus in a liver transplant recipient. | 2000 | Transplant. Proc. | pmid:10812156 |
| White SA et al. | Randomized trial comparing neoral and tacrolimus immunousuppression for recipients of renal transplants procured from different donor groups. | 2000 | Transplant. Proc. | pmid:10812132 |
| Glanemann M et al. | Higher immunosuppressive efficacy of mycophenolate mofetil in combination with FK 506 than in combination with cyclosporine A. | 2000 | Transplant. Proc. | pmid:10812095 |
| Chen XJ et al. | Positive and negative control of multidrug resistance by the Sit4 protein phosphatase in Kluyveromyces lactis. | 2000 | J. Biol. Chem. | pmid:10809730 |
| Riley L et al. | Cross-sensitivity reaction between tacrolimus and macrolide antibiotics. | 2000 | Bone Marrow Transplant. | pmid:10808214 |
| Pirsch J et al. | Coadministration of tacrolimus and mycophenolate mofetil in stable kidney transplant patients: pharmacokinetics and tolerability. | 2000 | J Clin Pharmacol | pmid:10806606 |
| Biggar SR and Crabtree GR | Chemically regulated transcription factors reveal the persistence of repressor-resistant transcription after disrupting activator function. | 2000 | J. Biol. Chem. | pmid:10801867 |
| Adachi S et al. | Successive expression and activation of NFAT family members during thymocyte differentiation. | 2000 | J. Biol. Chem. | pmid:10799559 |
| Moffatt SD et al. | STAT 6 up-regulation by FK506 in the presence of interleukin-4. | 2000 | Transplantation | pmid:10798785 |
| Borger P et al. | Cyclosporine, FK506, mycophenolate mofetil, and prednisolone differentially modulate cytokine gene expression in human airway-derived epithelial cells. | 2000 | Transplantation | pmid:10798763 |
| Qi S et al. | Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey. | 2000 | Transplantation | pmid:10798741 |
| Lu YM et al. | Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP. | 2000 | Neuron | pmid:10798404 |
| Gaweco AS et al. | Intragraft localization of activated nuclear factor kappaB in recurrent hepatitis C virus disease following liver transplantation. | 2000 | Hepatology | pmid:10796896 |
| Kiani A et al. | Manipulating immune responses with immunosuppressive agents that target NFAT. | 2000 | Immunity | pmid:10795734 |
| Yoshizawa K et al. | Time-specific occurrence of alopecia in neonatal C57BL mice treated with N-methyl-N-nitrosourea and the therapeutic efficacy of tacrolimus hydrate. | 2000 | Pathol. Int. | pmid:10792780 |
| Ramsay HM and Harden PN | Cyclosporin-induced flushing in a renal transplant recipient resolving after substitution with tacrolimus. | 2000 | Br. J. Dermatol. | pmid:10792253 |
| Neckermann G et al. | Atopic dermatitis-like symptoms in hypomagnesaemic hairless rats are prevented and inhibited by systemic or topical SDZ ASM 981. | 2000 | Br. J. Dermatol. | pmid:10792216 |
| Katayama Y et al. | [Studies on brain pyruvate dehydrogenase (PDH) activity and energy metabolites during ischemia and reperfusion]. | 1999 | Rinsho Shinkeigaku | pmid:10791103 |
| Kataoka T and Nagai K | Involvement of FK506-sensitive and insensitive granule exocytosis pathways in perforin-dependent target cell lysis mediated by a CD8+ CTL clone. | 2000 | Immunol. Lett. | pmid:10789681 |
| Gonin JM | Maintenance immunosuppression: new agents and persistent dilemmas. | 2000 | Adv Ren Replace Ther | pmid:10782729 |
| Vestergaard C et al. | The NC/Nga mouse: a model for atopic dermatitis. | 2000 | Mol Med Today | pmid:10782068 |
| Chini EN and Walker H | FK506 (tacrolimus) increases halothane-induced Ca2+ release from skeletal muscle sarcoplasmic reticulum. | 2000 | Anesthesiology | pmid:10781282 |
| Peters D et al. | Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. | 2000 | Blood | pmid:10779414 |
| Attur MG et al. | Differential anti-inflammatory effects of immunosuppressive drugs: cyclosporin, rapamycin and FK-506 on inducible nitric oxide synthase, nitric oxide, cyclooxygenase-2 and PGE2 production. | 2000 | Inflamm. Res. | pmid:10778917 |
| Yamani MH et al. | Efficacy of tacrolimus in patients with steroid-resistant cardiac allograft cellular rejection. | 2000 | J. Heart Lung Transplant. | pmid:10775813 |
| Kraiss LW et al. | Fluid flow activates a regulator of translation, p70/p85 S6 kinase, in human endothelial cells. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10775131 |
| pmid:10773614 | ||||
| Outeda MacÃas M et al. | Tacrolimus-itraconazole interaction in a kidney transplant patient. | 2000 | Ann Pharmacother | pmid:10772445 |
| Fernández-Miranda C et al. | Plasma homocysteine levels in renal transplanted patients on cyclosporine or tacrolimus therapy: effect of treatment with folic acid. | 2000 | Clin Transplant | pmid:10770414 |
| Klein BC et al. | Influence of mycophenolic acid and FK-506 on human platelet activation in vitro. | 2000 | Kidney Blood Press. Res. | pmid:10765114 |