tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Sarcoidosis D012507 13 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Hyperglycemia D006943 21 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Duraj F et al. [Intestinal transplantation. The first Swedish transplantation of the small intestine in an adult patient with pseudoobstruction]. 1998 Lakartidningen pmid:9700261
Matsumoto T et al. Influence of FK506 on experimental atherosclerosis in cholesterol-fed rabbits. 1998 Atherosclerosis pmid:9699896
[Tacrolimus in kidney transplantation. Bürgenstock, Switzerland, 20 March 1998]. 1998 Dtsch. Med. Wochenschr. pmid:9697633
Rejto PA and Verkhivker GM Molecular anchors with large stability gaps ensure linear binding free energy relationships for hydrophobic substituents. 1998 Pac Symp Biocomput pmid:9697196
Mihatsch MJ et al. The side-effects of ciclosporine-A and tacrolimus. 1998 Clin. Nephrol. pmid:9696431
Moriwaki A et al. An immunosuppressant, FK506, protects against neuronal dysfunction and death but has no effect on electrographic and behavioral activities induced by systemic kainate. 1998 Neuroscience pmid:9692722
Ding JM et al. A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock. 1998 Nature pmid:9690474
Kilmartin DJ et al. Tacrolimus (FK506) in failed cyclosporin A therapy in endogenous posterior uveitis. 1998 Ocul. Immunol. Inflamm. pmid:9689640
Tsuzuki S et al. FK506 (tacrolimus) inhibits extravasation of lymphoid cells by abrogating VLA-4/VCAM-1 mediated transendothelial migration. 1998 FEBS Lett. pmid:9688583
Medh RD et al. Agonist-specific modulation of glucocorticoid receptor-mediated transcription by immunosuppressants. 1998 Mol. Cell. Endocrinol. pmid:9685211
Peces R et al. Alloimmune haemolytic anaemia resulting from anti-A and anti-B antibody induced by group O graft in renal transplant recipients. 1998 Nephrol. Dial. Transplant. pmid:9681751
Grupp C et al. Haemolytic uraemic syndrome (HUS) during treatment with cyclosporin A after renal transplantation--is tacrolimus the answer? 1998 Nephrol. Dial. Transplant. pmid:9681701
Hultsch T et al. Direct evidence that FK506 inhibition of FcepsilonRI-mediated exocytosis from RBL mast cells involves calcineurin. 1998 Arch. Dermatol. Res. pmid:9681677
Van Leent EJ et al. Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. 1998 Arch Dermatol pmid:9681343
Denesyuk AI et al. Analogous conformations of both binding and effector regions in cyclosporin A, FK506 and rapamycin. 1998 Comput. Chem. pmid:9680690
Sanchez-Campos S et al. Cholestasis and alterations of glutathione metabolism induced by tacrolimus (FK506) in the rat. 1998 Transplantation pmid:9679826
Fisher NC et al. Chronic renal failure following liver transplantation: a retrospective analysis. 1998 Transplantation pmid:9679823
Onuma H et al. A calcineurin inhibitor, FK506, blocks voltage-gated calcium channel-dependent LTP in the hippocampus. 1998 Neurosci. Res. pmid:9678635
Salowe SP and Hermes JD Competitive and slow-binding inhibition of calcineurin by drug x immunophilin complexes. 1998 Arch. Biochem. Biophys. pmid:9675023
Yardin C et al. FK506 antagonizes apoptosis and c-jun protein expression in neuronal cultures. 1998 Neuroreport pmid:9674596