Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shin TH et al. | Formulation and in vivo pharmacokinetic evaluation of ethyl cellulose-coated sustained release multiple-unit system of tacrolimus. | 2018 | Int. J. Biol. Macromol. | pmid:29277422 |
De Lemos-Bonotto M et al. | A systematic review and meta-analysis of second-line immunosuppressants for autoimmune hepatitis treatment. | 2018 | Eur J Gastroenterol Hepatol | pmid:29227329 |
Huo T et al. | Preparation and comparison of tacrolimus-loaded solid dispersion and self-microemulsifying drug delivery system by in vitro/in vivo evaluation. | 2018 | Eur J Pharm Sci | pmid:29222025 |
Karagun BS et al. | Eye Movement Disorders Following Allogeneic Bone Marrow Transplantation on FK506 (Tacrolimus) and Ganciclovir. | 2018 | J. Pediatr. Hematol. Oncol. | pmid:28731920 |
Gupta PC and Ram J | Comparative Evaluation of Tacrolimus Versus Interferon Alpha-2b Eye Drops in the Treatment of Vernal Keratoconjunctivitis: A Randomized, Double-Masked Study. | 2018 | Cornea | pmid:29040120 |
Banovic F et al. | Tacrolimus therapy for dermal arteritis of the nasal philtrum refractory to surgery and anti-inflammatory therapy (doxycycline/niacinamide and topical fluocinolone) in a dog. | 2018 | Vet. Dermatol. | pmid:28990239 |
Guan XF et al. | Population Pharmacokinetic Modeling of Diltiazem in Chinese Renal Transplant Recipients. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:28646274 |
Almeida-Paulo GN et al. | Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant. | 2018 | Pharmacogenomics J. | pmid:28094348 |
Liu YJ et al. | Pooled analysis of the comparative efficacy between tacrolimus and infliximab for ulcerative colitis. | 2018 | Medicine (Baltimore) | pmid:30095612 |
Garaix F et al. | Tacrolimus Granules for Oral Suspension as Post-Transplant Immunosuppression in Routine Medical Practice in France: The OPTIMOD Study. | 2018 | Ann. Transplant. | pmid:30093607 |
Wang DD et al. | Population pharmacokinetics of tacrolimus in paediatric systemic lupus erythematosus based on real-world study. | 2018 | J Clin Pharm Ther | pmid:29766530 |
Rigo-Bonnin R et al. | Different top-down approaches to estimate measurement uncertainty of whole blood tacrolimus mass concentration values. | 2018 | Clin. Biochem. | pmid:29750938 |
Kaya Z et al. | Tacrolimus-Induced Autoimmune Hemolytic Anemia in a Previously Reported Child With History of Thrombocytopenia Following Liver Transplant. | 2018 | Exp Clin Transplant | pmid:29633932 |
Nanmoku K et al. | Steroid Withdrawal Using Everolimus in ABO-Incompatible Kidney Transplant Recipients With Post-Transplant Diabetes Mellitus. | 2018 | Transplant. Proc. | pmid:29631750 |
Takeuchi K et al. | Comparison of Safety and Efficacy of Tacrolimus versus Infliximab for Active Ulcerative Colitis. | 2018 | Dig Dis | pmid:29050007 |
Mashiah J et al. | Topical pimecrolimus for paediatric cutaneous mastocytosis. | 2018 | Clin. Exp. Dermatol. | pmid:29460435 |
Chen ZH et al. | Adenovirus-mediated OX40Ig gene transfer induces long-term survival of orthotopic liver allograft in rats. | 2018 | Transpl. Immunol. | pmid:29454984 |
Yu K et al. | Tacrolimus nanoparticles based on chitosan combined with nicotinamide: enhancing percutaneous delivery and treatment efficacy for atopic dermatitis and reducing dose. | 2018 | Int J Nanomedicine | pmid:29317821 |
Yang MY et al. | High rates of secondary non-adherence causes decreased efficacy of 0.1% topical tacrolimus in adult eczema patients: results from a multicenter clinical trial. | 2018 | J Dermatolog Treat | pmid:28670943 |
Dheer D et al. | Tacrolimus: An updated review on delivering strategies for multifarious diseases. | 2018 | Eur J Pharm Sci | pmid:29277665 |