| MeSH term | MeSH ID | Detail |
|---|---|---|
| Insulin Resistance | D007333 | 99 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shui C et al. | The immunosuppressant rapamycin, alone or with transforming growth factor-beta, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand. | 2002 | Calcif. Tissue Int. | pmid:12202955 |
| Pradhan M et al. | Decline in renal function following thoracic organ transplantation in children. | 2002 | Am. J. Transplant. | pmid:12201367 |
| Tsinalis D et al. | Acute renal failure in a renal allograft recipient treated with intravenous immunoglobulin. | 2002 | Am. J. Kidney Dis. | pmid:12200824 |
| McAlister V | Predicting behavior of immunosuppressants in liver transplantation. | 2002 | Liver Transpl. | pmid:12200790 |
| Jain AK et al. | The interaction between antiretroviral agents and tacrolimus in liver and kidney transplant patients. | 2002 | Liver Transpl. | pmid:12200788 |
| Neff T et al. | Pharmacologically regulated in vivo selection in a large animal. | 2002 | Blood | pmid:12200362 |
| Escribano O et al. | Pretreatment with FK506 up-regulates insulin receptors in regenerating rat liver. | 2002 | Hepatology | pmid:12198647 |
| Mettang T et al. | Uraemic pruritus--new perspectives and insights from recent trials. | 2002 | Nephrol. Dial. Transplant. | pmid:12198205 |
| Cho YM et al. | A case showing complete insulin independence after severe diabetic ketoacidosis associated with tacrolimus treatment. | 2002 | Diabetes Care | pmid:12196452 |
| Guilbeau JM | Delayed wound healing with sirolimus after liver transplant. | 2002 | Ann Pharmacother | pmid:12196058 |
| Pawinski T et al. | Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus. | 2002 | Clin. Chem. | pmid:12194926 |
| Slowinski T et al. | Interaction of the endothelin system and calcineurin inhibitors after kidney transplantation. | 2002 | Clin. Sci. | pmid:12193131 |
| Christians U et al. | Mechanisms of clinically relevant drug interactions associated with tacrolimus. | 2002 | Clin Pharmacokinet | pmid:12190331 |
| Fox SC et al. | Platelet aggregation and intracellular calcium mobilisation responses are enhanced by cyclosporin A but not by pimecrolimus (SDZ ASM 981). | 2002 | Platelets | pmid:12189022 |
| Homma M et al. | False positive blood tacrolimus concentration in microparticle enzyme immunoassay. | 2002 | Biol. Pharm. Bull. | pmid:12186423 |
| Manzanares C | Therapeutic drug monitoring of tacrolimus: a moving matter. | 2002 Mar-Apr | Therapie | pmid:12185961 |
| Ferraresso M et al. | Conversion from cyclosporine to tacrolimus in pediatric kidney transplant recipients. | 2002 | Pediatr. Nephrol. | pmid:12185478 |
| Revill WP et al. | Genetically engineered analogs of ascomycin for nerve regeneration. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12183690 |
| Venkataramanan R et al. | Voriconazole inhibition of the metabolism of tacrolimus in a liver transplant recipient and in human liver microsomes. | 2002 | Antimicrob. Agents Chemother. | pmid:12183280 |
| Minder D et al. | Immunophilins and HIV-1 infection. | 2002 | Arch. Virol. | pmid:12181673 |
| Cheng H et al. | Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function. | 2002 | Mol. Biol. Cell | pmid:12181359 |
| Ma L et al. | Immunosuppressive effects of glucosamine. | 2002 | J. Biol. Chem. | pmid:12176986 |
| Zajicek A et al. | Thirteen years' experience in pediatric liver transplantation: differences between tacrolimus and cyclosporine. | 2002 | Transplant. Proc. | pmid:12176653 |
| Sindhi R et al. | Preliminary immunosuppression withdrawal strategies with sirolimus in children with liver transplants. | 2002 | Transplant. Proc. | pmid:12176651 |
| Asensio M et al. | Induction with basiliximab reduces acute rejection in pediatric liver transplant patients treated with tacrolimus and steroids. | 2002 | Transplant. Proc. | pmid:12176650 |
| Jain A et al. | Almost total absence of chronic rejection in primary pediatric liver transplantation under tacrolimus. | 2002 | Transplant. Proc. | pmid:12176649 |
| Petz W et al. | Experience with the use of basiliximab in liver transplantation--use in pediatric and adult recipients in combination with cyclosporine or tacrolimus. | 2002 | Transplant. Proc. | pmid:12176648 |
| Sindhi R et al. | Pharmacodynamics of sirolimus in transplanted children receiving tacrolimus. | 2002 | Transplant. Proc. | pmid:12176644 |
| Ojogho ON et al. | Mycophenolate mofetil without antibody induction in pediatric renal transplantation. | 2002 | Transplant. Proc. | pmid:12176641 |
| Sundberg AK et al. | Conversion from cyclosporine to tacrolimus is preferred by pediatric renal transplant recipients: a focus on opinions and outcomes. | 2002 | Transplant. Proc. | pmid:12176640 |
| Webb NJ et al. | Pharmacokinetics of tacrolimus in paediatric renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176639 |
| El-Sabrout R et al. | Improved lipid profile and blood sugar control in pediatric renal transplant recipients using sirolimus-tacrolimus combination. | 2002 | Transplant. Proc. | pmid:12176638 |
| Ciancio G et al. | Effect of daclizumab, tacrolimus, and mycophenolate mofetil in pediatric first renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176637 |
| El-Sabrout R et al. | Rejection-free protocol using sirolimus-tacrolimus combination for pediatric renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176636 |
| Hasegawa A et al. | Optimal use of tacrolimus in living donor renal transplantation in children. | 2002 | Transplant. Proc. | pmid:12176635 |
| Filler G et al. | One-year glomerular filtration rate predicts graft survival in pediatric renal recipients: a randomized trial of tacrolimus vs cyclosporine microemulsion. | 2002 | Transplant. Proc. | pmid:12176634 |
| Woeste G et al. | Tacrolimus/mycophenolate mofetil vs cyclosporine A/Azathioprine after simultaneous pancreas and kidney transplantation: five-year results of a randomized study. | 2002 | Transplant. Proc. | pmid:12176629 |
| Burke GW et al. | Steroid-resistant acute rejection following SPK: importance of maintaining therapeutic dosing in a triple-drug regimen. | 2002 | Transplant. Proc. | pmid:12176628 |
| Land W et al. | Tacrolimus versus cyclosporine in primary simultaneous pancreas-kidney transplantation: preliminary results at 1 year of a large multicenter trial. | 2002 | Transplant. Proc. | pmid:12176625 |
| Dette K et al. | Daclizumab and ATG versus ATG in combination with tacrolimus, mycophenolate mofetil, and steroids in simultaneous [correction of simultaneus] pancreas-kidney transplantation: analysis of early outcome. | 2002 | Transplant. Proc. | pmid:12176624 |
| Rigotti P et al. | Antilymphocyte induction is no longer necessary in simultaneous pancreas and kidney transplantation. | 2002 | Transplant. Proc. | pmid:12176623 |
| Khwaja K et al. | Pancreas transplantation in cross-match-positive recipients using cyclosporine- or tacrolimus-based immunosuppression. | 2002 | Transplant. Proc. | pmid:12176621 |
| Fieguth HG et al. | Tacrolimus for treatment of bronchiolitis obliterans syndrome after unilateral and bilateral lung transplantation. | 2002 | Transplant. Proc. | pmid:12176613 |
| Baran DA et al. | Predictors of early renal insufficiency in cardiac transplant recipients initiated on tacrolimus. | 2002 | Transplant. Proc. | pmid:12176609 |
| van Riemsdijk IC et al. | Improvement of cardiovascular risk factors in heart transplant recipients after conversion from cyclosporine to tacrolimus: a role of the TGF-beta system. | 2002 | Transplant. Proc. | pmid:12176606 |
| Chan MC et al. | Conversion of cyclosporine to tacrolimus for refractory or persistent myocardial rejection. | 2002 | Transplant. Proc. | pmid:12176601 |
| Baran DA et al. | Tacrolimus and cardiac transplantation: a comparison of monotherapy and steroid-dependent patients. | 2002 | Transplant. Proc. | pmid:12176599 |
| Uber PA et al. | Steroid weaning in heart transplantation is associated with decreased B-type natriuretic peptide: surrogate evidence for cardiac adaptation. | 2002 | Transplant. Proc. | pmid:12176598 |
| Pham SM et al. | Sirolimus and tacrolimus in clinical cardiac transplantation. | 2002 | Transplant. Proc. | pmid:12176597 |
| Undre NA and Stevenson PJ | Pharmacokinetics of tacrolimus in heart transplantation. | 2002 | Transplant. Proc. | pmid:12176596 |
| Baran DA et al. | A novel tacrolimus dosing strategy in cardiac transplantation: drug levels, renal function, and biopsy results. | 2002 | Transplant. Proc. | pmid:12176595 |
| Omoto K et al. | Adverse events in renal transplantation under tacrolimus/mycophnolate mofetil immunosuppression: a single-center experience. | 2002 | Transplant. Proc. | pmid:12176591 |
| Tanabe K et al. | Prospective analysis of thrombotic microangiopathy after renal transplantation: comparison between cyclosporine and tacrolimus immunosuppression. | 2002 | Transplant. Proc. | pmid:12176590 |
| El Haggan W et al. | One year evolution of bone mineral density in kidney transplant recipients receiving tacrolimus versus cyclosporine. | 2002 | Transplant. Proc. | pmid:12176589 |
| Suwelack B et al. | Replacement of calcineurin inhibitors by mycophenolate mofetil: effect on hemoglobine levels. | 2002 | Transplant. Proc. | pmid:12176585 |
| Boucher A et al. | Impact of immunosuppressive regimen on cardiovascular risk factors in kidney transplant recipients. | 2002 | Transplant. Proc. | pmid:12176582 |
| Artz MA et al. | Randomized conversion from cyclosporine to tacrolimus in renal transplant patients: improved lipid profile and unchanged plasma homocysteine levels. | 2002 | Transplant. Proc. | pmid:12176579 |
| Akioka K et al. | Diabetes in renal transplant recipients treated with tacrolimus. | 2002 | Transplant. Proc. | pmid:12176570 |
| Baid S et al. | Tacrolimus-associated posttransplant diabetes mellitus in renal transplant recipients: role of hepatitis C infection. | 2002 | Transplant. Proc. | pmid:12176569 |
| Koefoed-Nielsen PB and Jørgensen KA | Alterations in calcineurin phosphatase activity in tacrolimus-treated renal transplant patients. | 2002 | Transplant. Proc. | pmid:12176559 |
| Pozzetto U et al. | Effects of immunosuppressive regimens on plasma levels of transforming growth factor-beta 1 in renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176558 |
| Uchida K et al. | Usefulness of monitoring of AUC(0-4h) during the induction period of immunosuppressive therapy with tacrolimus after renal transplantation. | 2002 | Transplant. Proc. | pmid:12176556 |
| Toda F et al. | Tacrolimus trough level adjustment after administration of fluconazole to kidney recipients. | 2002 | Transplant. Proc. | pmid:12176555 |
| Sifontis NM et al. | Clinically significant drug interaction between basiliximab and tacrolimus in renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176554 |
| Saito K et al. | Study of pharmacokinetic parameters of tacrolimus by different oral administration periods in renal transplantation. | 2002 | Transplant. Proc. | pmid:12176553 |
| van Duijnhoven EM et al. | Evidence that fasting does not significantly affect trough levels of tacrolimus in stable renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176552 |
| Jørgensen KA et al. | Two-hour blood tacrolimus levels are not superior to trough levels as estimates of the area under the curve in tacrolimus-treated renal transplant patients. | 2002 | Transplant. Proc. | pmid:12176551 |
| Rodrigo E et al. | Histopathological findings according to Banff-97 classification system comparing tacrolimus versus cyclosporine. | 2002 | Transplant. Proc. | pmid:12176550 |
| Baran DA et al. | Tacrolimus and new onset diabetes mellitus: the effect of steroid weaning. | 2002 | Transplant. Proc. | pmid:12176547 |
| Citterio F et al. | Steroid withdrawal from tacrolimus-based therapy in renal transplant patients. | 2002 | Transplant. Proc. | pmid:12176545 |
| Boots JM et al. | Early steroid withdrawal in renal transplantation with tacrolimus dual therapy: a pilot study. | 2002 | Transplant. Proc. | pmid:12176542 |
| Boots JM et al. | Risk of adrenal insufficiency with steroid maintenance therapy in renal transplantation. | 2002 | Transplant. Proc. | pmid:12176541 |
| Beaunoyer M et al. | Low-dose tacrolimus, trough-monitored mycophenolate mofetil, and planned steroid withdrawal for cadaveric kidney transplantation: a single center experience. | 2002 | Transplant. Proc. | pmid:12176540 |
| Moons P et al. | Steroids may compromise quality of life of renal transplant recipients on a tacrolimus-based regimen. | 2002 | Transplant. Proc. | pmid:12176538 |
| Sola E et al. | Low-dose and rapid steroid withdrawal in renal transplant patients treated with tacrolimus and mycophenolate mofetil. | 2002 | Transplant. Proc. | pmid:12176537 |
| Citterio F et al. | Conversion to tacrolimus immunosuppression in renal transplant recipients: 12-month follow-up. | 2002 | Transplant. Proc. | pmid:12176535 |
| Ushigome H et al. | Immunosuppression in cadaveric renal transplant recipients from non-heart-beating donors in a single center. | 2002 | Transplant. Proc. | pmid:12176533 |
| Scolari MP et al. | Acute rejection after renal transplantation with tacrolimus-based therapy in conditions of normal clinical practice. | 2002 | Transplant. Proc. | pmid:12176529 |
| Tanabe K et al. | Improved outcome of minor-mismatched living renal allografts under tacrolimus immunosuppression. | 2002 | Transplant. Proc. | pmid:12176528 |
| Okamoto M et al. | Tacrolimus-based immunosuppression in renal transplantation: 78 experiences in a single Japanese center. | 2002 | Transplant. Proc. | pmid:12176527 |
| Wayman MR et al. | Two-year outcome in renal allograft recipients comparing neoral-led with tacrolimus-led therapy. | 2002 | Transplant. Proc. | pmid:12176526 |
| Gurkan A et al. | Comparison of tacrolimus and neoral-based immunosuppressive regimens in renal transplantation patients: singles-center experience. | 2002 | Transplant. Proc. | pmid:12176525 |
| Dietl KH | Oral dosing of tacrolimus and cyclosporine microemulsion--results from a large multicenter study in renal transplantation. | 2002 | Transplant. Proc. | pmid:12176524 |
| Campos HH and Abbud Filho M | One-year follow-up of a Brazilian randomized multicenter study comparing tacrolimus versus cyclosporine in kidney transplantation. | 2002 | Transplant. Proc. | pmid:12176523 |
| Youseff N and Small S | A retrospective analysis of a sirolimus/prograf regimen for the prevention of acute rejection in recipients of primary mismatched renal allografts. | 2002 | Transplant. Proc. | pmid:12176522 |
| Shapiro R et al. | A pilot trial of tacrolimus, sirolimus, and steroids in renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176521 |
| Rashid I et al. | Medium-term outcome using sirolimus-tacrolimus combination in adult renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176520 |
| Craig AM et al. | A cost-effectiveness analysis of tacrolimus versus cyclosporine microemulsion following kidney transplantation. | 2002 | Transplant. Proc. | pmid:12176519 |
| Garcia I | Efficacy and safety of dual versus triple tacrolimus-based therapy in kidney transplantation: two-year follow-up. | 2002 | Transplant. Proc. | pmid:12176516 |
| Montagnino G et al. | Efficacy and safety of tacrolimus compared with cyclosporine microemulsion in kidney transplantation: twelve-month follow-up. | 2002 | Transplant. Proc. | pmid:12176515 |
| Charpentier B | A three arm study comparing immediate tacrolimus therapy with ATG induction therapy followed by either tacrolimus or cyclosporine in adult renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176511 |
| Ciancio G et al. | Effect of daclizumab, tacrolimus and mycophenolate mofetil in racial minority first renal transplant recipients. | 2002 | Transplant. Proc. | pmid:12176508 |
| Sonnenday CJ et al. | Preemptive therapy with plasmapheresis/intravenous immunoglobulin allows successful live donor renal transplantation in patients with a positive cross-match. | 2002 | Transplant. Proc. | pmid:12176507 |
| Coupes BM et al. | Tacrolimus monotherapy in renal transplantation: four-year data. | 2002 | Transplant. Proc. | pmid:12176506 |
| Burke GW et al. | Randomized trial of three different immunosuppressive regimens to prevent chronic renal allograft rejection. | 2002 | Transplant. Proc. | pmid:12176505 |
| Uchida K et al. | Excellent 3-year results following living-donor kidney transplantation and tacrolimus immunosuppression in Japan. | 2002 | Transplant. Proc. | pmid:12176503 |
| Takahashi K et al. | Successful results after 3 years' tacrolimus immunosuppression in ABO-incompatible kidney transplantation recipients in Japan. | 2002 | Transplant. Proc. | pmid:12176502 |
| Yoshimura N et al. | Safety analysis following tacrolimus immunosuppression in renal transplant recipients in Japan: 3-year results in over 1000 patients. | 2002 | Transplant. Proc. | pmid:12176501 |
| Takahara S et al. | Excellent results following 3 years of tacrolimus immunosuppression in kidney transplantation recipients in Japan: overall analysis of more than 1000 patients. | 2002 | Transplant. Proc. | pmid:12176500 |
| Budde K et al. | Five year outcome of tacrolimus rescue therapy in late rejection after renal transplantation. | 2002 | Transplant. Proc. | pmid:12176499 |