| MeSH term | MeSH ID | Detail |
|---|---|---|
| Insulin Resistance | D007333 | 99 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jain A et al. | Reasons why some children receiving tacrolimus therapy require steroids more than 5 years post liver transplantation. | 2001 | Pediatr Transplant | pmid:11328546 |
| Frühwirth M et al. | Rotavirus infection as cause of tacrolimus elevation in solid-organ-transplanted children. | 2001 | Pediatr Transplant | pmid:11328545 |
| Mittal N et al. | Tacrolimus and diarrhea: pathogenesis of altered metabolism. | 2001 | Pediatr Transplant | pmid:11328543 |
| Dicarlo JB and McCall CO | Pharmacologic alternatives for severe atopic dermatitis. | 2001 | Int. J. Dermatol. | pmid:11328387 |
| Mollee P et al. | Combination therapy with tacrolimus and anti-thymocyte globulin for the treatment of steroid-resistant acute graft-versus-host disease developing during cyclosporine prophylaxis. | 2001 | Br. J. Haematol. | pmid:11328304 |
| Sche PP et al. | Corrigendum to: "Display cloning: functional identification of natural product receptors using cDNA-phage display" [Chemistry & Biology 6 (1999) 707-716]. | 2001 | Chem. Biol. | pmid:11325595 |
| Kawada N et al. | Role of mast cells in antigen-induced airway inflammation and bronchial hyperresponsiveness in rats. | 2001 | Jpn. J. Pharmacol. | pmid:11325017 |
| Kulkarni P | Review: uveitis and immunosuppressive drugs. | 2001 | J Ocul Pharmacol Ther | pmid:11324985 |
| Weinberg JM and Silverberg NB | A kinder, gentler therapy? | 2001 | Cutis | pmid:11324387 |
| Kennedy DS and Linden GJ | Resolution of gingival overgrowth following change from cyclosporin to tacrolimus therapy in a renal transplant patient. | 2000 | J Ir Dent Assoc | pmid:11323935 |
| Lang-Lazdunski L et al. | The effects of FK506 on neurologic and histopathologic outcome after transient spinal cord ischemia induced by aortic cross-clamping in rats. | 2001 | Anesth. Analg. | pmid:11323353 |
| Gaziev D and Lucarelli G | Novel approaches to the treatment of chronic graft-versus-host disease. | 2001 | Expert Opin Investig Drugs | pmid:11322865 |
| StrestÃková P et al. | Different mechanisms in inhibition of rat macrophage nitric oxide synthase expression by FK 506 and cyclosporin A. | 2001 | Immunopharmacol Immunotoxicol | pmid:11322650 |
| Russell RK et al. | Systemic absorption with complications during topical tacrolimus treatment for orofacial Crohn disease. | 2001 | J. Pediatr. Gastroenterol. Nutr. | pmid:11321395 |
| Pohanka E et al. | [Dosage and monitoring of tacrolimus after kidney transplantation]. | 2000 | Dtsch. Med. Wochenschr. | pmid:11320722 |
| Smith KM and Van Etten RA | Activation of c-Abl kinase activity and transformation by a chemical inducer of dimerization. | 2001 | J. Biol. Chem. | pmid:11320088 |
| Takatsuki M et al. | Analysis of alloreactivity and intragraft cytokine profiles in living donor liver transplant recipients with graft acceptance. | 2001 | Transpl. Immunol. | pmid:11316071 |
| Yoshimoto T et al. | Cyclosporin A, but not FK506, prevents the downregulation of phosphorylated Akt after transient focal ischemia in the rat. | 2001 | Brain Res. | pmid:11311876 |
| Rumora L et al. | MKP-1 as a target for pharmacological manipulations in PC12 cell survival. | 2001 | Neurochem. Int. | pmid:11311446 |
| Freyschmidt-Paul P et al. | Current and potential agents for the treatment of alopecia areata. | 2001 | Curr. Pharm. Des. | pmid:11311114 |
| Monegal A et al. | Bone mass and mineral metabolism in liver transplant patients treated with FK506 or cyclosporine A. | 2001 | Calcif. Tissue Int. | pmid:11310351 |
| Sheehy EC et al. | Oral health in children undergoing liver transplantation. | 2000 | Int J Paediatr Dent | pmid:11310095 |
| Topical tacrolimus for treatment of atopic dermatitis. | 2001 | Med Lett Drugs Ther | pmid:11309535 | |
| Jones NF et al. | Comparison of long-term immunosuppression for limb transplantation using cyclosporine, tacrolimus, and mycophenolate mofetil: implications for clinical composite tissue transplantation. | 2001 | Plast. Reconstr. Surg. | pmid:11304605 |
| Trotter JF et al. | Liver transplantation using sirolimus and minimal corticosteroids (3-day taper). | 2001 | Liver Transpl. | pmid:11303295 |
| Mardini M et al. | Cyclosporine and FK506 differentially regulate the sarcolemmal Na(+)-K(+) pump. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11303073 |
| Shiraishi S et al. | Up-regulation of cell surface sodium channels by cyclosporin A, FK506, and rapamycin in adrenal chromaffin cells. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11303055 |
| Arima H et al. | Contribution of P-glycoprotein to the enhancing effects of dimethyl-beta-cyclodextrin on oral bioavailability of tacrolimus. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11303042 |
| Li S et al. | Combined host-conditioning with CTLA4-Ig, tacrolimus, anti-lymphocyte serum, and low-dose radiation leads to stable mixed hematopoietic chimerism. | 2001 | Exp. Hematol. | pmid:11301194 |
| Luger T et al. | SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis. | 2001 | Br. J. Dermatol. | pmid:11298538 |
| Harper J et al. | First experience of topical SDZ ASM 981 in children with atopic dermatitis. | 2001 | Br. J. Dermatol. | pmid:11298537 |
| Griffiths CE | Ascomycin: an advance in the management of atopic dermatitis. | 2001 | Br. J. Dermatol. | pmid:11298524 |
| Yada T et al. | Its8, a fission yeast homolog of Mcd4 and Pig-n, is involved in GPI anchor synthesis and shares an essential function with calcineurin in cytokinesis. | 2001 | J. Biol. Chem. | pmid:11297516 |
| Ishikawa M et al. | [Blood concentrations and side effects of tacrolimus in a living renal transplantation]. | 2001 | Masui | pmid:11296433 |
| Lener EV et al. | Successful treatment of erosive lichen planus with topical tacrolimus. | 2001 | Arch Dermatol | pmid:11295919 |
| Macchi-Andanson M et al. | Failure of traditional trough levels to predict tacrolimus concentrations. | 2001 | Ther Drug Monit | pmid:11294512 |
| van Gelder T et al. | Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. | 2001 | Ther Drug Monit | pmid:11294511 |
| Fortin JF et al. | Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1. | 2001 | Blood | pmid:11290602 |
| Zoeteweij JP et al. | Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus. | 2001 | Blood | pmid:11290600 |
| Lunz JG et al. | Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs. | 2001 | Am. J. Pathol. | pmid:11290556 |
| Fredduzzi S et al. | Nitro-aspirin (NCX4016) reduces brain damage induced by focal cerebral ischemia in the rat. | 2001 | Neurosci. Lett. | pmid:11290402 |
| Trimarchi H et al. | Cyclosporine-associated thrombotic microangiopathy during daclizumab induction: a suggested therapeutic approach. | 2001 | Nephron | pmid:11287781 |
| Kasper RC et al. | Anetoderma arising in cutaneous B-cell lymphoproliferative disease. | 2001 | Am J Dermatopathol | pmid:11285407 |
| Schwrer H et al. | Pantoprazole and cyclosporine or tacrolimus. | 2001 | Aliment. Pharmacol. Ther. | pmid:11284790 |
| Krisp A and Hoffmann R | [Letter concerning the article by E.C.Bornhövd, E.Schuller, T.Bieber, A.Wollenberg: "Immunosuppressive macrolides and their use in dermatology". Der Hautarzt (2000) 51:646-654]. | 2001 | Hautarzt | pmid:11284076 |
| Tahara K et al. | Experimental small bowel transplantation using newborn intestine in rats: III. Long-term cryopreservation of rat newborn intestine. | 2001 | J. Pediatr. Surg. | pmid:11283886 |
| Martel J et al. | [Subcutaneous mycosis due to Scopulariopsis brevicaulis in an immunocompromised patient]. | 2001 | Ann Dermatol Venereol | pmid:11275588 |
| von Schnakenburg C et al. | Post-transplant epididymitis and orchitis following Listeria monocytogenes septicaemia. | 2000 | Pediatr Transplant | pmid:11272610 |
| Dmitrewski J et al. | Steroid withdrawal 3 months after liver transplantation--does FK 506 confer any advantage over cyclosporin? | 1994 | Transpl. Int. | pmid:11271342 |
| Uemoto S et al. | Long-term use of FK 506 in living related liver transplantation. | 1994 | Transpl. Int. | pmid:11271341 |
| Mor E et al. | Comparison of short and long-term renal function in liver transplant patients receiving cyclosporin or FK 506. | 1994 | Transpl. Int. | pmid:11271340 |
| Wong P et al. | FK 506 rescue therapy for intractable liver allograft rejection. | 1994 | Transpl. Int. | pmid:11271339 |
| Otto G et al. | Corticosteroids and concomitant medication in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation. | 1994 | Transpl. Int. | pmid:11271338 |
| Devlin J et al. | FK 506 primary immunosuppression following emergency liver transplantation for fulminant hepatic failure. European FK 506 Study Liver Group. | 1994 | Transpl. Int. | pmid:11271328 |
| Winkler M et al. | Optimal FK 506 dosage in patients under primary immunosuppression following liver transplantation. | 1994 | Transpl. Int. | pmid:11271312 |
| Moutabarrik A et al. | Effect of immunosuppressive agents FK 506 and cyclosporin and steroids on the expression of IL-6 and its receptor by stimulated lymphocytes and monocytes. | 1994 | Transpl. Int. | pmid:11271305 |
| Metcalfe S et al. | FK 506 and cyclosporin each block antigen-induced T cell receptor signalling that is dependent on CD4 co-receptor and operates in the absence of detectable cytoplasmic calcium fluxes. | 1994 | Transpl. Int. | pmid:11271304 |
| Platz KP et al. | Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients. | 1994 | Transpl. Int. | pmid:11271297 |
| Ishii T et al. | Immunodepressants ameliorate normothermic ischemia injury to the rat liver by down-regulating tumor necrosis factor, not by alleviation of lipid peroxidative injury. | 1994 | Transpl. Int. | pmid:11271294 |
| Trocha K et al. | Neurological examinations after liver transplantation concerning patients under corticosteroid immunosuppression and either FK 506 or cyclosporin. | 1994 | Transpl. Int. | pmid:11271273 |
| D'Silva M et al. | The immunomodulatory effects of a novel agent, leflunomide, in rat cardiac allotransplantation. | 1994 | Transpl. Int. | pmid:11271257 |
| Mueller AR et al. | Neurotoxicity after orthotopic liver transplantation in cyclosporin A- and FK 506-treated patients. | 1994 | Transpl. Int. | pmid:11271254 |
| McMaster P | Patient and graft survival in the European Multicentre Liver Study--FK 506 vs cyclosporin A. | 1994 | Transpl. Int. | pmid:11271239 |
| Bismuth H et al. | Focus on intractable rejection: 6-month results of the European multicentre liver study of FK 506 and cyclosporin A. | 1994 | Transpl. Int. | pmid:11271231 |
| Neuhaus P et al. | Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation. | 1994 | Transpl. Int. | pmid:11271222 |
| Two-year follow-up study of the efficacy and safety of FK 506 in kidney transplant patients. Japanese FK 506 Study Group. | 1994 | Transpl. Int. | pmid:11271216 | |
| Devlin J et al. | Renal complications and development of hypertension in the European study of FK 506 and cyclosporin in primary liver transplant recipients. | 1994 | Transpl. Int. | pmid:11271207 |
| Yano K et al. | Effects of intrahepatic arterial and intraportal administration of FK 506 on liver allograft survival in rats. | 1994 | Transpl. Int. | pmid:11271200 |
| Undre N and Möller A | Pharmacokinetic interpretation of FK 506 levels in blood and in plasma during a European randomised study in primary liver transplant patients. The FK 506 European Study Group. | 1994 | Transpl. Int. | pmid:11271189 |
| Ericzon B et al. | Glucose metabolism in liver transplant recipients treated with FK 506 or cyclosporin in the European multicentre study. | 1994 | Transpl. Int. | pmid:11271178 |
| Bekersky I et al. | Effect of time of meal consumption on bioavailability of a single oral 5 mg tacrolimus dose. | 2001 | J Clin Pharmacol | pmid:11269569 |
| Jain A et al. | Pharmacokinetics of mycophenolic acid after mycophenolate mofetil administration in liver transplant patients treated with tacrolimus. | 2001 | J Clin Pharmacol | pmid:11269567 |
| Reimer J et al. | Quality of life after kidney transplantation--the impact of tacrolimus. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267573 |
| Lo A et al. | Ganciclovir prophylaxis for cytomegalovirus infection in simultaneous kidney-pancreas transplant recipients receiving tacrolimus, mycophenolate mofetil, and prednisone. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267516 |
| Spada M et al. | A cause of late graft dysfunction after liver transplantation in children: de-novo autoimmune hepatitis. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267495 |
| Molmenti EP et al. | Incidence, management, and outcome of posttransplant lymphoproliferative disease in pediatric liver transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267487 |
| Owen ER et al. | Peripheral nerve regeneration in human hand transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267484 |
| Lo A et al. | Limited benefits of induction with monoclonal antibody to interleukin-2 receptor in combination with tacrolimus, mycophenolate mofetil, and steroids in simultaneous kidney-pancreas transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267477 |
| McCauley J et al. | Long-term lipid metabolism in combined kidney-pancreas transplant recipients under tacrolimus immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267475 |
| Kahl A et al. | Long-term prednisolone withdrawal after pancreas and kidney transplantation in patients treated with ATG, tacrolimus, and mycophenolate mofetil. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267473 |
| Burke GW et al. | Ten-year survival after simultaneous pancreas/kidney transplantation with bladder drainage and tacrolimus-based immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267467 |
| Lo A et al. | Outcome of simultaneous kidney-pancreas transplantation in African-American recipients: a case control study. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267465 |
| Jordan ML et al. | Steroid withdrawal for pancreas transplants under tacrolimus immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267456 |
| Treede H et al. | Incidence and spectrum of infections in lung transplanted patients: comparison of four different immunosuppressive protocols. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267444 |
| Mehra MR et al. | Racial differences in clinical outcome using tacrolimus and mycophenolate mofetil immunosuppression in heart transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267442 |
| Mehra MR et al. | A randomized comparison of an immunosuppressive strategy using tacrolimus and cyclosporine in black heart transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267438 |
| Banerjee R et al. | Coadministration of itraconazole and tacrolimus after thoracic organ transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267435 |
| Uber PA et al. | Ethnic disparities in the pharmacologic characteristics of tacrolimus in heart transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267428 |
| Rabkin JM et al. | Pharmacoeconomic study of tacrolimus-based versus cyclosporine-based immunosuppressive therapy following liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267411 |
| Heffron TG et al. | Daclizumab induction in liver transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267408 |
| Langrehr JM et al. | A prospective, randomized trial with quadruple versus dual tacrolimus-based induction after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267404 |
| Pirenne J et al. | Standard cyclosporine A-based versus completely steroid-free FK506-based immunosuppression after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267396 |
| van den Berg AP et al. | Recurrent HCV infection reduces the requirement for tacrolimus after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267375 |
| Groetzner J et al. | Tacrolimus or cyclosporine for immunosuppression after cardiac transplantation: which treatment reveals more side effects during long-term follow-up? | 2001 Feb-Mar | Transplant. Proc. | pmid:11267373 |
| Heffron TG et al. | Single-dose induction with daclizumab immediately after liver transplantation in pediatric patients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267368 |
| Langrehr JM et al. | IL-2 receptor antibody induction increases the risk for chronic rejection after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267360 |
| Markus BH et al. | Daclizumab induction therapy in combination with tacrolimus. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267354 |
| Shokouh-Amiri MH et al. | The importance of early prevention of renal dysfunction in liver transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267345 |
| Mohamed MA et al. | TGF-beta expression in protocol transplant liver biopsies: a comparative study between cyclosporine-A (CyA) and tacrolimus (FK 506) immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267336 |
| Mueller AR et al. | Influence of immunosuppression on patient survival after liver transplantation for hepatitis C. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267321 |