tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Keratosis, Actinic D055623 3 associated lipids
Invasive Pulmonary Aspergillosis D055744 1 associated lipids
Latent Tuberculosis D055985 1 associated lipids
Netherton Syndrome D056770 1 associated lipids
Leukoencephalopathies D056784 3 associated lipids
Central Serous Chorioretinopathy D056833 1 associated lipids
Thrombotic Microangiopathies D057049 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Candidiasis, Invasive D058365 2 associated lipids
End Stage Liver Disease D058625 1 associated lipids
Retrognathia D063173 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Scorpion Stings D065008 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Jungersted JM et al. Effects of topical corticosteroid and tacrolimus on ceramides and irritancy to sodium lauryl sulphate in healthy skin. 2011 Acta Derm. Venereol. pmid:21365172
de la Rosa Carrillo D and Christensen OB Treatment of chronic discoid lupus erythematosus with topical tacrolimus. 2004 Acta Derm. Venereol. pmid:15202845
Zattra E et al. Labial melanotic macule after application of topical tacrolimus: two case reports. 2010 Acta Derm. Venereol. pmid:20814635
Granlund H et al. Treatment of lichenified atopic eczema with tacrolimus ointment. 2001 Aug-Sep Acta Derm. Venereol. pmid:11720192
Reitamo S et al. Long-term treatment with 0.1% tacrolimus ointment in adults with atopic dermatitis: results of a two-year, multicentre, non-comparative study. 2007 Acta Derm. Venereol. pmid:17721647
Mandelin J et al. One-year treatment with 0.1% tacrolimus ointment versus a corticosteroid regimen in adults with moderate to severe atopic dermatitis: A randomized, double-blind, comparative trial. 2010 Acta Derm. Venereol. pmid:20169301
Ujiie H et al. Successful treatment of nail lichen planus with topical tacrolimus. 2010 Acta Derm. Venereol. pmid:20169322
Honda Y et al. Disseminated Mycobacterium mantenii infection with multiple purulent cutaneous lesions. 2015 Acta Derm. Venereol. pmid:25881714
Jensen JM et al. Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right-left arm trial. 2013 Acta Derm. Venereol. pmid:23571785
Kirsner RS et al. Safety and efficacy of tacrolimus ointment versus pimecrolimus cream in the treatment of patients with atopic dermatitis previously treated with corticosteroids. 2010 Acta Derm. Venereol. pmid:20107727
Fukamachi S et al. Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis. 2009 Acta Derm. Venereol. pmid:19326000
Jacobs F et al. New approach in combined therapy of perifolliculitis capitis abscedens et suffodiens. 2011 Acta Derm. Venereol. pmid:21681358
Chittock J et al. Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. 2015 Acta Derm. Venereol. pmid:25594610
Masuda K et al. Increased levels of serum interleukin-16 in adult type atopic dermatitis. 2003 Acta Derm. Venereol. pmid:12926794
Yamamoto T and Nishioka K Deep dermatophytosis during topical tacrolimus therapy for psoriasis. 2003 Acta Derm. Venereol. pmid:12926803
Sand C Topical tacrolimus ointment may induce skin tags in treated patients. 2003 Acta Derm. Venereol. pmid:12926817
Park SW et al. Topical tacrolimus (FK506): treatment failure in four cases of alopecia universalis. 2002 Acta Derm. Venereol. pmid:12430746
Jedlicková H et al. Granuloma faciale successfully treated with topical tacrolimus: a case report. 2008 Acta Dermatovenerol Alp Pannonica Adriat pmid:18454269
Thaçi D and Salgo R The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. 2007 Acta Dermatovenerol Alp Pannonica Adriat pmid:17992459
Vukićević J et al. Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. 2009 Acta Dermatovenerol Alp Pannonica Adriat pmid:19350187