Yem AW et al. |
The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13. |
1992 |
J. Biol. Chem. |
pmid:1371107
|
Park ST et al. |
PPIase catalysis by human FK506-binding protein proceeds through a conformational twist mechanism. |
1992 |
J. Biol. Chem. |
pmid:1371117
|
Bishop DK and Li W |
Cyclosporin A and FK506 mediate differential effects on T cell activation in vivo. |
1992 |
J. Immunol. |
pmid:1371128
|
Hatfield SM and Roehm NW |
Cyclosporine and FK506 inhibition of murine mast cell cytokine production. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1371158
|
Takaya S et al. |
The adverse impact on liver transplantation of using positive cytotoxic crossmatch donors. |
1992 |
Transplantation |
pmid:1371195
|
Francavilla A et al. |
Inhibition of liver, kidney, and intestine regeneration by rapamycin. |
1992 |
Transplantation |
pmid:1371198
|
Matsukawa W et al. |
Effects of a new immunosuppressive agent, FK506, in rats with active Heymann nephritis. |
1992 |
J. Lab. Clin. Med. |
pmid:1371298
|
Sampson BA and Gotschlich EC |
Neisseria meningitidis encodes an FK506-inhibitable rotamase. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1371354
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Liu J et al. |
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. |
1992 |
Biochemistry |
pmid:1373650
|
Adachi A et al. |
Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: change of T cell subsets. |
1992 |
Intern. Med. |
pmid:1373661
|
Fruman DA et al. |
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1373887
|
Lake JR et al. |
Maintenance immunosuppression after liver transplantation. |
1992 |
Semin. Liver Dis. |
pmid:1373916
|
Taormina D et al. |
Stability and sorption of FK 506 in 5% dextrose injection and 0.9% sodium chloride injection in glass, polyvinyl chloride, and polyolefin containers. |
1992 |
Am J Hosp Pharm |
pmid:1373936
|
Ochiai T |
[Advances in the fundamentals and therapeutic use of immunosuppressive agents]. |
1992 |
Arerugi |
pmid:1374229
|
de Paulis A et al. |
Anti-inflammatory effect of FK-506 on human skin mast cells. |
1992 |
J. Invest. Dermatol. |
pmid:1281861
|
Ericzon BG et al. |
The effect of FK506 treatment on pancreaticoduodenal allotransplantation in the primate. |
1992 |
Transplantation |
pmid:1376501
|
Tze WJ et al. |
FK 506--an effective immunosuppressant in achieving long-term functional islet allograft survival in diabetic rats. |
1992 |
Transplant. Proc. |
pmid:1376509
|
Yasunami Y et al. |
Induction of donor-specific unresponsiveness in rat islet allografts by FK 506. |
1992 |
Transplant. Proc. |
pmid:1376510
|
Kai N et al. |
A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. |
1992 |
Transplant. Proc. |
pmid:1376511
|
Ricordi C et al. |
Effect of FK 506 on human pancreatic islets following renal subcapsular transplantation in diabetic nude mice. |
1992 |
Transplant. Proc. |
pmid:1376512
|
Hisanaga M et al. |
Successful combination therapy with FK 506 and 15-deoxyspergualin in pancreatic islet xenografting. |
1992 |
Transplant. Proc. |
pmid:1376513
|
Ogasa N et al. |
Successful transplantation of newborn rat intestine as a free graft. |
1992 |
Transplant. Proc. |
pmid:1376514
|
Graeb C et al. |
Cytoimmunologic monitoring of small bowel allograft recipients. |
1992 |
Transplant. Proc. |
pmid:1376515
|
Akutsu I et al. |
[Inhibitory effects of cyclosporin A and FK-506 on eosinophil chemotactic factor activity in culture supernatants of mononuclear cells from asthmatics]. |
1992 |
Arerugi |
pmid:1280086
|
Bergstrand H and Lundquist B |
Human basophil histamine release is differently affected by inhibitors of calmodulin, diacylglycerol kinase and peptidyl prolyl cis-trans isomerase in a secretagogue specific manner. |
1992 |
Allergy |
pmid:1280915
|
Barry JM |
Immunosuppressive drugs in renal transplantation. A review of the regimens. |
1992 |
Drugs |
pmid:1281071
|
Stiff DD et al. |
Metabolism of FK 506 in differentially induced rat liver microsomes. |
1992 |
Res. Commun. Chem. Pathol. Pharmacol. |
pmid:1281332
|
Foor F et al. |
Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeast. |
1992 |
Nature |
pmid:1281518
|
Goldfeld AE et al. |
Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1281550
|
Morikawa K et al. |
The distinct effects of FK506 on the activation, proliferation, and differentiation of human B lymphocytes. |
1992 |
Transplantation |
pmid:1281561
|
Moutabarrik A et al. |
FK506-induced kidney tubular cell injury. |
1992 |
Transplantation |
pmid:1281562
|
Murthy JN et al. |
Radioreceptor assay for quantifying FK-506 immunosuppressant in whole blood. |
1992 |
Clin. Chem. |
pmid:1377995
|
Takai K et al. |
Effects of FK506 on rat thymic epithelial cells; immunohistochemical study. |
1992 |
Thymus |
pmid:1378235
|
Dutz JP et al. |
Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. |
1992 |
Int. Immunol. |
pmid:1378297
|
Kenmochi T et al. |
[The effect of FK506 on segmental pancreas allograft in mongrel dogs]. |
1992 |
Nihon Geka Gakkai Zasshi |
pmid:1378526
|
Mouzaki A et al. |
Cyclosporin A and FK506 prevent the derepression of the IL-2 gene in mitogen-induced primary T lymphocytes. |
1992 |
Cytokine |
pmid:1378764
|
Ramamoorthy S et al. |
Selective impairment of taurine transport by cyclosporin A in a human placental cell line. |
1992 |
Pediatr. Res. |
pmid:1378960
|
Armitage JM et al. |
Clinical trial of FK 506 immunosuppression in adult cardiac transplantation. |
1992 |
Ann. Thorac. Surg. |
pmid:1379032
|
First MR |
Renal transplantation for the nephrologist: new immunosuppressive drugs. |
1992 |
Am. J. Kidney Dis. |
pmid:1371201
|
Steiner JP et al. |
High brain densities of the immunophilin FKBP colocalized with calcineurin. |
1992 |
Nature |
pmid:1380130
|
Aperia A et al. |
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380157
|
Nielsen JB et al. |
Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380159
|
Calvo V et al. |
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380162
|
Price DJ et al. |
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. |
1992 |
Science |
pmid:1380182
|
Granelli-Piperno A |
SRC-related proto-oncogenes and transcription factors in primary human T cells: modulation by cyclosporin A and FK506. |
1992 |
J. Autoimmun. |
pmid:1380242
|
Reem GH |
Molecular mode of action of cyclosporin and FK506 in human thymocytes. |
1992 |
J. Autoimmun. |
pmid:1380243
|
Bach JF |
Immunointervention in autoimmune diseases from cellular selectivity to autoantigen specificity. |
1992 |
J. Autoimmun. |
pmid:1380245
|
Wiederrecht G et al. |
Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex. |
1992 |
J. Biol. Chem. |
pmid:1383226
|
Morris RE |
Immunopharmacology of new xenobiotic immunosuppressive molecules. |
1992 |
Semin. Nephrol. |
pmid:1384096
|
Hendey B et al. |
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. |
1992 |
Science |
pmid:1384129
|
Roberti I et al. |
Evidence that the systematic analysis of bile cytology permits monitoring of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1384182
|
Langrehr JM et al. |
Evidence that indefinite survival of small bowel allografts achieved by a brief course of cyclosporine or FK506 is not due to systemic hyporesponsiveness. |
1992 |
Transplantation |
pmid:1384185
|
McCarthy SA et al. |
The effects of immunosuppressive drugs on the regulation of activation-induced apoptotic cell death in thymocytes. |
1992 |
Transplantation |
pmid:1384186
|
Dhar DK et al. |
The salutary effect of FK506 in ischemia-reperfusion injury of the canine liver. |
1992 |
Transplantation |
pmid:1384188
|
Ericzon BG et al. |
FK506-induced impairment of glucose metabolism in the primate--studies in pancreatic transplant recipients and in nontransplanted animals. |
1992 |
Transplantation |
pmid:1384189
|
Mizuno K et al. |
Modulation of multidrug resistance by immunosuppressive agents: cyclosporin analogues, FK506 and mizoribine. |
1992 Jan-Feb |
Anticancer Res. |
pmid:1373592
|
Arai S et al. |
The impact of FK506 on graft coronary disease of rat cardiac allograft--a comparison with cyclosporine. |
1992 Jul-Aug |
J. Heart Lung Transplant. |
pmid:1379829
|
Fagiuoli S et al. |
FK 506: a new immunosuppressive agent for organ transplantation. Pharmacology, mechanism of action and clinical applications. |
1992 Jul-Aug |
Ital J Gastroenterol |
pmid:1381245
|
Tong J et al. |
Effect of FK-506 and cyclosporin A on in vitro CFU-GM growth in severe aplastic anemia patients. |
1992 Jul-Aug |
Haematologica |
pmid:1385279
|
Nazer H et al. |
FK 506 associated disorders in liver transplantation. |
1992 May-Jun |
J. Gastroenterol. Hepatol. |
pmid:1377038
|
Bowman H and Lennard TW |
Immunosuppressive drugs. |
1992 Nov 4-17 |
Br J Hosp Med |
pmid:1282440
|
Sattler M et al. |
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. |
1992 Sep-Oct |
Drug Metab. Dispos. |
pmid:1385058
|
Kuroki H et al. |
Effect of FK 506 and donor-specific blood transfusion on the rat composite tissue limb allograft and the mechanism of long-term graft survival. |
1993 |
Transplant. Proc. |
pmid:7679833
|
Azhderian EM et al. |
Nucleus associated FK 506 binding proteins with potential relevance to FK 506 immunosuppression. |
1993 |
Transplant. Proc. |
pmid:7679834
|
Porayko MK et al. |
Nephrotoxicity of FK 506 and cyclosporine when used as primary immunosuppression in liver transplant recipients. |
1993 |
Transplant. Proc. |
pmid:7679835
|
Shapiro R et al. |
Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report. |
1993 |
Transplant. Proc. |
pmid:7679836
|
Nelson PA et al. |
Immunosuppressive activity of [MeBm2t]1-, D-diaminobutyryl-8-, and D-diaminopropyl-8-cyclosporin analogues correlates with inhibition of calcineurin phosphatase activity. |
1993 |
J. Immunol. |
pmid:7680683
|
Piekoszewski W and Jusko WJ |
Plasma protein binding of tacrolimus in humans. |
1993 |
J Pharm Sci |
pmid:7680714
|
Ning YM and Sánchez ER |
Potentiation of glucocorticoid receptor-mediated gene expression by the immunophilin ligands FK506 and rapamycin. |
1993 |
J. Biol. Chem. |
pmid:7681058
|
Saeki T et al. |
Human P-glycoprotein transports cyclosporin A and FK506. |
1993 |
J. Biol. Chem. |
pmid:7681059
|
Fabrega AJ et al. |
Enhancement of allograft survival by single intraoperative donor-specific blood transfusion combined with FK506. |
1993 |
Transplantation |
pmid:7506458
|
Jain A et al. |
FK506 and pregnancy in liver transplant patients. |
1993 |
Transplantation |
pmid:7506459
|
Winkler ME et al. |
Successful pregnancy in a patient after liver transplantation maintained on FK 506. |
1993 |
Transplantation |
pmid:7506460
|
Yoshizawa K et al. |
Establishment of Epstein-Barr virus-associated lymphoma cell line SUBL with t(2;3)(p11;q27) from a liver transplant patient. |
1993 |
Cancer Genet. Cytogenet. |
pmid:7506636
|
Distant DA and Gonwa TA |
The kidney in liver transplantation. |
1993 |
J. Am. Soc. Nephrol. |
pmid:7691205
|
Muthukkumar S et al. |
Elevation of cytosolic calcium is sufficient to induce growth inhibition in a B cell lymphoma. |
1993 |
Eur. J. Immunol. |
pmid:7691606
|
Wesselborg S et al. |
Triggering via the alternative CD2 pathway induces apoptosis in activated human T lymphocytes. |
1993 |
Eur. J. Immunol. |
pmid:7691614
|
Schulz BS et al. |
Increased expression of epidermal IL-8 receptor in psoriasis. Down-regulation by FK-506 in vitro. |
1993 |
J. Immunol. |
pmid:7691948
|
Travis J |
Making molecular matches in the cell. |
1993 |
Science |
pmid:7694368
|
Jusko WJ and Kobayashi M |
Therapeutic monitoring of tacrolimus (FK 506) |
1993 |
Ther Drug Monit |
pmid:7694395
|
Kunz J and Hall MN |
Cyclosporin A, FK506 and rapamycin: more than just immunosuppression. |
1993 |
Trends Biochem. Sci. |
pmid:7694398
|
Bierer BE et al. |
Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. |
1993 |
Curr. Opin. Immunol. |
pmid:7694595
|
Akamine S et al. |
[Effect of FK-506 on bronchial healing of canine lung allografts]. |
1993 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:7685803
|
Partaledis JA and Berlin V |
The FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulum. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7685904
|
Sykes K et al. |
Proline isomerases function during heat shock. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7685914
|
Suzuki S et al. |
Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. |
1993 |
Transplantation |
pmid:7685932
|
Abu-Elmagd K et al. |
Recent advances in hepatic transplantation at the University of Pittsburgh. |
1993 |
Clin Transpl |
pmid:7522528
|
Ueki M et al. |
Diabetogenic effects of FK506 on renal subcapsular islet isografts in rat. |
1993 |
Diabetes Res. Clin. Pract. |
pmid:7688276
|
Pleyer U et al. |
Ocular absorption of topically applied FK506 from liposomal and oil formulations in the rabbit eye. |
1993 |
Invest. Ophthalmol. Vis. Sci. |
pmid:7688360
|
Machida M |
[Effect of temperature on plasma concentration of FK506]. |
1993 |
Nippon Hinyokika Gakkai Zasshi |
pmid:7688443
|
Schmid FX |
Prolyl isomerase: enzymatic catalysis of slow protein-folding reactions. |
1993 |
Annu Rev Biophys Biomol Struct |
pmid:7688608
|
Kino T and Goto T |
Discovery of FK-506 and update. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689804
|
Parsons WH et al. |
FK-506--a novel immunosuppressant. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689805
|
Zenke G et al. |
Molecular mechanisms of immunosuppression by cyclosporins. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689806
|
Clardy J |
Structural studies of complexed FK-506 binding protein. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7689808
|
Meadows RP et al. |
Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR. |
1993 |
Biochemistry |
pmid:7678499
|
Jiang H et al. |
Anti-tumor-promoting action of FK506, a potent immunosuppressive agent. |
1993 |
Carcinogenesis |
pmid:7678785
|
Naito M et al. |
Enhancement of cellular accumulation of cyclosporine by anti-P-glycoprotein monoclonal antibody MRK-16 and synergistic modulation of multidrug resistance. |
1993 |
J. Natl. Cancer Inst. |
pmid:7678867
|
Barthelmess IB and Tropschug M |
FK506-binding protein of Neurospora crassa (NcFKBP) mediates sensitivity to the immunosuppressant FK506; resistant mutants identify two loci. |
1993 |
Curr. Genet. |
pmid:7679056
|