| MeSH term | MeSH ID | Detail |
|---|---|---|
| Keratosis, Actinic | D055623 | 3 associated lipids |
| Invasive Pulmonary Aspergillosis | D055744 | 1 associated lipids |
| Latent Tuberculosis | D055985 | 1 associated lipids |
| Netherton Syndrome | D056770 | 1 associated lipids |
| Leukoencephalopathies | D056784 | 3 associated lipids |
| Central Serous Chorioretinopathy | D056833 | 1 associated lipids |
| Thrombotic Microangiopathies | D057049 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Candidiasis, Invasive | D058365 | 2 associated lipids |
| End Stage Liver Disease | D058625 | 1 associated lipids |
| Retrognathia | D063173 | 1 associated lipids |
| Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
| Scorpion Stings | D065008 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Satomura K et al. | Pharmacokinetics of FK 506 in living-related liver transplantation. | 1996 | Transplant. Proc. | pmid:8623209 |
| Loss M et al. | Glucose and lipid metabolism in liver transplant patients under long-term tacrolimus (FK 506) monotherapy. | 1996 | Transplant. Proc. | pmid:8623210 |
| Fryer JP et al. | Bacterial translocation in a large-animal model of small-bowel transplantation. Portal vs systemic venous drainage and the effect of tacrolimus immunosuppression. | 1996 | Arch Surg | pmid:8546583 |
| Bechstein WO et al. | Tacrolimus (FK 506) therapy is associated with a significant reduction in immunosuppressive treatment failures following primary liver transplantation. | 1996 | Transplant. Proc. | pmid:8623211 |
| Sher LS et al. | Tacrolimus (FK 506) for rescue of chronic rejection following orthotopic liver transplantation. | 1996 | Transplant. Proc. | pmid:8623212 |
| Millis JM et al. | Treatment of steroid-resistant rejection with tacrolimus prior to OKT3 in liver transplant recipients. | 1996 | Transplant. Proc. | pmid:8623213 |
| Washburn WK et al. | Tacrolimus rescue therapy for renal allograft rejection refractory to cyclosporine-based immunosuppression. | 1996 | Transplant. Proc. | pmid:8623214 |
| Regazzi MB et al. | Interaction between FK 506 and diltiazem in an animal model. | 1996 | Transplant. Proc. | pmid:8623215 |
| Hashikura Y et al. | Immunosuppressant switching between cyclosporine and tacrolimus after liver transplantation. | 1996 | Transplant. Proc. | pmid:8623218 |
| Pirenne J et al. | Bone marrow augmentation of kidney allografts can cause graft-versus-host disease in immunosuppressed recipients. | 1996 | Transplant. Proc. | pmid:8623472 |
| Ciancio G et al. | Human donor bone marrow cells can enhance hyporeactivity in renal transplantation using maintenance FK 506 and OKT3 induction therapy. | 1996 | Transplant. Proc. | pmid:8623473 |
| D'Silva M et al. | Immunosuppressive effect of brequinar on rat cardiac allograft survival in combination with leflunomide or FK 506. | 1996 | Transplant. Proc. | pmid:8623476 |
| Klintmalm GB | Clinical use of FK 506 in liver transplantation. | 1996 | Transplant. Proc. | pmid:8623484 |
| Butt TR et al. | Molecular basis of immunosuppressive drug action: regulation of steroid receptor-mediated transcription by FK 506. | 1996 | Transplant. Proc. | pmid:8623486 |
| Mugiya S et al. | Renal blood flow and serotonin metabolism in tacrolimus treated rats. | 1996 | Int. J. Urol. | pmid:8776615 |
| Dmitrewski J et al. | Recurrence of primary biliary cirrhosis in the liver allograft: the effect of immunosuppression. | 1996 | J. Hepatol. | pmid:8778189 |
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| Newell KA et al. | Posttransplant lymphoproliferative disease in pediatric liver transplantation. Interplay between primary Epstein-Barr virus infection and immunosuppression. | 1996 | Transplantation | pmid:8779685 |
| Lufft V et al. | Incidence of Pneumocystis carinii pneumonia after renal transplantation. Impact of immunosuppression. | 1996 | Transplantation | pmid:8779695 |
| Craescu CT et al. | Three-dimensional structure of the immunophilin-like domain of FKBP59 in solution. | 1996 | Biochemistry | pmid:8780506 |
| Singh N and Yu VL | Prophylaxis for cytomegalovirus disease after liver transplant. | 1996 | Clin. Infect. Dis. | pmid:8783744 |
| Wu J et al. | Reversal of multidrug resistance by tacrolimus hydrate. | 1996 | Methods Find Exp Clin Pharmacol | pmid:9121220 |
| Perego C et al. | Orthotopic liver-small bowel transplantation in pigs: study of immunologic parameters during therapy with FK 506-based immunosuppressive regimens. | 1996 | Transplant. Proc. | pmid:8907908 |
| Alessiani M et al. | Combined FK 506 and mycophenolate mofetil immunosuppression prolongs survival after small bowel transplantation in pigs. | 1996 | Transplant. Proc. | pmid:8907922 |
| Cohen DS et al. | Porcine small bowel transplantation with rapamycin-based induction immunosuppression and short-course cyclosporine or FK 506 therapy. | 1996 | Transplant. Proc. | pmid:8907923 |
| Toyama Y et al. | Prolonged small bowel graft survival using photochemotherapy and low-dose FK 506. | 1996 | Transplant. Proc. | pmid:8907924 |
| Yamada T et al. | Synergistic effect of FK 506 and trifluoperazine on the immunosuppression in rat small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8907927 |
| Rossi G et al. | Results of orthotopic liver-small bowel transplantation in the pig using different immunosuppressive regimens. | 1996 | Transplant. Proc. | pmid:8907932 |
| Platz KP et al. | Immunosuppressive power and limitations of FK 506 for prevention and treatment of graft-vs-host disease after small bowel transplantation. | 1996 | Transplant. Proc. | pmid:8907933 |
| Velio P et al. | Rejection and survival after total orthotopic liver-small bowel allotransplantation in pigs immunosuppressed with FK 506. | 1996 | Transplant. Proc. | pmid:8907936 |
| Sonatore LM et al. | The utility of FK506-binding protein as a fusion partner in scintillation proximity assays: application to SH2 domains. | 1996 | Anal. Biochem. | pmid:8811923 |
| Jonas S et al. | Conversion to tacrolimus after liver transplantation. | 1996 | Transpl. Int. | pmid:8748407 |
| Cooley HM et al. | Resolution of pyoderma gangrenosum using tacolimus (FK-506) | 1996 | Aust N Z J Med | pmid:8744629 |
| Hashino S et al. | Antitumor effect in cyclosporine A- or FK506-treated mice after syngeneic bone marrow transplantation. | 1996 | Leuk. Lymphoma | pmid:8726416 |
| Ichinari H et al. | Effects of portal venous inoculation with donor splenocytes on lung allograft survival in dogs. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8751494 |
| Steiner JP et al. | Immunophilin regulation of neurotransmitter release. | 1996 | Mol. Med. | pmid:8784785 |
| Sunyecz JA et al. | Lymphoproliferative disorder involving the cervix in a patient being treated with FK-506. | 1996 | Gynecol. Oncol. | pmid:8751565 |
| Herzog D et al. | Combined bowel-liver transplantation in an infant with microvillous inclusion disease. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8732907 |
| Licitra EJ and Liu JO | A three-hybrid system for detecting small ligand-protein receptor interactions. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8917502 |
| Woodle ES et al. | Treatment of acute glomerular rejection with FK 506. | 1996 | Clin Transplant | pmid:8826664 |
| Guckelberger O et al. | Does the choice of primary immunosuppression influence the prevalence of cardiovascular risk factors after liver transplantation? | 1996 | Transplant. Proc. | pmid:8962230 |
| Braun F et al. | Clinical relevance of monitoring tacrolimus: comparison of microparticle enzyme immunoassay, enzyme-linked immunosorbent assay, and liquid chromatography mass spectrometry in renal transplant recipients converted from cyclosporine to tacrolimus. | 1996 | Transplant. Proc. | pmid:8962231 |
| Wilczek HE et al. | Renal transplant histopathologic changes during the first year in patients with tacrolimus (FK 506). | 1996 | Transplant. Proc. | pmid:8962232 |
| Yussim A et al. | Conversion from cyclosporine to tacrolimus in hepatic and renal transplantation. | 1996 | Transplant. Proc. | pmid:8962233 |
| Golling M et al. | Tacrolimus reduction improves glucose metabolism and insulin secretion after liver transplantation. | 1996 | Transplant. Proc. | pmid:8962234 |
| Platz KP et al. | Incidence and outcome of chronic rejection in CyA- and FK 506-treated patients. | 1996 | Transplant. Proc. | pmid:8962235 |
| Mollison KW et al. | Discovery of FK 506 analogues that are nontoxic to mouse pancreatic beta cells in vitro but show diabetogenic potential when administered to the rat. | 1996 | Transplant. Proc. | pmid:8962236 |
| Degawa H et al. | Blocking of ICAM-1 and LFA-1 in rat liver transplantation. | 1996 | Transplant. Proc. | pmid:8658695 |
| Watanabe K et al. | Immunosuppressive effect of bactobolamine in rat liver allotransplantation. | 1996 | Transplant. Proc. | pmid:8658697 |
| Tojimbara T et al. | Cyclosporine and tacrolimus both suppress activation of Kupffer cells in vitro. | 1996 | Transplant. Proc. | pmid:8658704 |
| Yuzawa K et al. | Topical immunosuppression in skin grafting with FK 506 ointment. | 1996 | Transplant. Proc. | pmid:8658707 |
| Yagura K et al. | Pharmacokinetic characteristics of two types of liposomal FK 506. | 1996 | Transplant. Proc. | pmid:8658708 |
| Ogawa N et al. | Suppressive effects of combination therapy with mizoribine and FK 506 on the development of accelerated coronary artery disease and myocardial rejection after heart transplantation. | 1996 | Transplant. Proc. | pmid:8658710 |
| Yoshida Y et al. | Effect of lipoprostaglandin E1 in concordant xenografts. | 1996 | Transplant. Proc. | pmid:8658716 |
| Kawauchi M et al. | Which are the target vessels of xeno- and allo-lung rejection?--a primate single lung transplantation study. | 1996 | Transplant. Proc. | pmid:8658719 |
| Shapiro R et al. | "Suboptimal" kidney donors: the experience with tacrolimus-based immunosuppression. | 1996 | Transplantation | pmid:8932264 |
| Mysliwiec J et al. | The effect of tacrolimus (FK506) and cyclosporin A (CyA) on peripheral serotonergic mechanisms in uremic rats. | 1996 | Thromb. Res. | pmid:8837316 |
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| Lamb GD and Stephenson DG | Effects of FK506 and rapamycin on excitation-contraction coupling in skeletal muscle fibres of the rat. | 1996 | J. Physiol. (Lond.) | pmid:8842013 |
| Curran CF et al. | Acute overdoses of tacrolimus. | 1996 | Transplantation | pmid:8932293 |
| Tanaka K et al. | Effect of cyclosporin analogues and FK506 on transcellular transport of daunorubicin and vinblastine via P-glycoprotein. | 1996 | Pharm. Res. | pmid:8842048 |
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| Chen BG et al. | Inhibition by CsA and FK506 of the in vitro proliferative response of gamma delta T cells on stimulation with anti-TCR delta monoclonal antibody. | 1996 | Transpl. Immunol. | pmid:8843593 |
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