tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Pruritus Vulvae D011539 1 associated lipids
Central Serous Chorioretinopathy D056833 1 associated lipids
Feline Acquired Immunodeficiency Syndrome D016181 1 associated lipids
Budd-Chiari Syndrome D006502 1 associated lipids
Porokeratosis D017499 1 associated lipids
Lentigo D007911 1 associated lipids
Mutism D009155 1 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Cervical Intraepithelial Neoplasia D018290 1 associated lipids
Migraine with Aura D020325 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

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Authors Title Published Journal PubMed Link
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Bakos L and Bakos RM Focal acne during topical tacrolimus therapy for vitiligo. 2007 Arch Dermatol pmid:17875902
Ruzicka T et al. Tacrolimus: the drug for the turn of the millennium? 1999 Arch Dermatol pmid:10328199
Laffitte E et al. Erosive pustular dermatosis of the scalp: treatment with topical tacrolimus. 2003 Arch Dermatol pmid:12810500
Chu J et al. Topical tacrolimus is a useful adjunctive therapy for bullous pemphigoid. 2003 Arch Dermatol pmid:12810523
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Thiers BH Topical tacrolimus: treatment failure in a patient with alopecia areata. 2000 Arch Dermatol pmid:10632221
Rotunda AM et al. Hyperkeratotic plaques on the palms and soles. Palmoplantar lichen planus, hyperkeratotic variant. 2004 Arch Dermatol pmid:15492196
Laffitte E and Panizzon RG Is topical tacrolimus really an effective therapy for Hailey-Hailey disease? 2004 Arch Dermatol pmid:15492199
Systemic tacrolimus (FK 506) is effective for the treatment of psoriasis in a double-blind, placebo-controlled study. The European FK 506 Multicentre Psoriasis Study Group. 1996 Arch Dermatol pmid:8629845
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Van Leent EJ et al. Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. 1998 Arch Dermatol pmid:9681343
Choi CJ and Nghiem P Tacrolimus ointment in the treatment of chronic cutaneous graft-vs-host disease: a case series of 18 patients. 2001 Arch Dermatol pmid:11559218
Mandelin J et al. Effect of oral acetylsalicylic acid on burning caused by tacrolimus ointment in patients with atopic dermatitis. 2010 Arch Dermatol pmid:20956662
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Lally A et al. Penile pyoderma gangrenosum treated with topical tacrolimus. 2005 Arch Dermatol pmid:16172330
Passeron T et al. Topical tacrolimus and the 308-nm excimer laser: a synergistic combination for the treatment of vitiligo. 2004 Arch Dermatol pmid:15381545
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Byrd JA et al. Response of oral lichen planus to topical tacrolimus in 37 patients. 2004 Arch Dermatol pmid:15611431
Santos-Juanes J et al. Topical tacrolimus: an effective therapy for Zoon balanitis. 2004 Arch Dermatol pmid:15611442
Milingou M et al. Alcohol intolerance and facial flushing in patients treated with topical tacrolimus. 2004 Arch Dermatol pmid:15611445
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Carroll CL et al. Topical tacrolimus ointment combined with 6% salicylic acid gel for plaque psoriasis treatment. 2005 Arch Dermatol pmid:15655140
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Ciurea AM et al. Complete and durable clinical response of malignant pyoderma to tacrolimus in combination with dapsone and prednisone. 2010 Arch Dermatol pmid:20083712
Ward KM et al. Eyelash trichomegaly associated with systemic tacrolimus. 2006 Arch Dermatol pmid:16490862
Ostovari N et al. Lack of efficacy of tacrolimus in the treatment of vitiligo in the absence of UV-B exposure. 2006 Arch Dermatol pmid:16490866
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Böhm M et al. Successful treatment of anogenital lichen sclerosus with topical tacrolimus. 2003 Arch Dermatol pmid:12873890
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Sugiura H et al. Long-term efficacy of tacrolimus ointment for recalcitrant facial erythema resistant to topical corticosteroids in adult patients with atopic dermatitis. 2000 Arch Dermatol pmid:10926750
Byrd JA et al. Recalcitrant symptomatic vulvar lichen planus: response to topical tacrolimus. 2004 Arch Dermatol pmid:15210463
Shah KN and Yan AC Low but detectable serum levels of tacrolimus seen with the use of very dilute, extemporaneously compounded formulations of tacrolimus ointment in the treatment of patients with netherton syndrome. 2006 Arch Dermatol pmid:17043199
Antille C et al. Induction of rosaceiform dermatitis during treatment of facial inflammatory dermatoses with tacrolimus ointment. 2004 Arch Dermatol pmid:15096374
Banky JP et al. Successful treatment of epidermolysis bullosa pruriginosa with topical tacrolimus. 2004 Arch Dermatol pmid:15262686
Passeron T et al. Treatment of oral erosive lichen planus with 1% pimecrolimus cream: a double-blind, randomized, prospective trial with measurement of pimecrolimus levels in the blood. 2007 Arch Dermatol pmid:17438179
Bruce A and Rogers RS New and old therapeutics for oral ulcerations. 2007 Arch Dermatol pmid:17438186
Qureshi A and Fischer MA Topical calcineurin inhibitors revisited. 2007 Arch Dermatol pmid:17438195
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Cheng A and Mann C Oral erosive lichen planus treated with efalizumab. 2006 Arch Dermatol pmid:16785369
Sniezek PJ et al. Annular atrophic plaques on the arms of a 57-year-old woman. 2006 Arch Dermatol pmid:16785386
Allen DM and Esterly NB Significant systemic absorption of tacrolimus after topical application in a patient with lamellar ichthyosis. 2002 Arch Dermatol pmid:12225004
Hall VC et al. Ocular mucous membrane pemphigoid and ocular pemphigus vulgaris treated topically with tacrolimus ointment. 2003 Arch Dermatol pmid:12925404