| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hauser IA and Neumayer HN | Tacrolimus and cyclosporine efficacy in high-risk kidney transplantation. European Multicentre Tacrolimus (FK506) Renal Study Group. | 1998 | Transpl. Int. | pmid:9664948 |
| Kokado Y et al. | Low-dose tacrolimus (FK506)-based immunosuppressive protocol in living donor renal transplantation. | 1998 | Transpl. Int. | pmid:9664945 |
| Stockwell BR and Schreiber SL | TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins. | 1998 | Chem. Biol. | pmid:9662508 |
| Nagayasu T et al. | Expression of proliferating cell nuclear antigen in bronchial epithelium after lung transplantation in the rat. | 1998 | J. Heart Lung Transplant. | pmid:9662091 |
| Lai MM et al. | Cain, a novel physiologic protein inhibitor of calcineurin. | 1998 | J. Biol. Chem. | pmid:9660798 |
| Tsujikawa A et al. | Tacrolimus (FK506) attenuates leukocyte accumulation after transient retinal ischemia. | 1998 | Stroke | pmid:9660400 |
| Bader G et al. | Reduction of cyclosporine-induced gingival overgrowth following a change to tacrolimus. A case history involving a liver transplant patient. | 1998 | J. Periodontol. | pmid:9660343 |
| McBride WJ et al. | Allogeneic fetal intestinal transplantation with FK506 immunosuppression. | 1998 | J. Pediatr. Surg. | pmid:9660232 |
| Fujino T et al. | The immunosuppressive compound FK506 does not affect expulsion of Echinostoma trivolvis in C3H mice. | 1998 | Parasitol. Res. | pmid:9660146 |
| Le Bihan S et al. | Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells. | 1998 | Mol. Endocrinol. | pmid:9658403 |
| Sasa H et al. | Hepatic extraction of tacrolimus in rats with experimental liver diseases. | 1998 | Biol. Pharm. Bull. | pmid:9657047 |
| Nishioka T et al. | [Is tacrolimus effective for ongoing renal allograft rejection?]. | 1998 | Hinyokika Kiyo | pmid:9656112 |
| Morozumi K et al. | [Current topics of the rejection pathology in human renal allografts]. | 1998 | Hinyokika Kiyo | pmid:9656109 |
| Tamura K | [Multiple actions of tacrolimus and cyclosporin A as specific inhibitors of calcineurin]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655970 |
| Matsui H et al. | [Physiological role of calcineurin in central nervous system]. | 1998 | Tanpakushitsu Kakusan Koso | pmid:9655961 |
| Cetinkale O et al. | Involvement of neutrophils in ischemia-reperfusion injury of inguinal island skin flaps in rats. | 1998 | Plast. Reconstr. Surg. | pmid:9655420 |
| Kommers T et al. | Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. | 1998 | Neurosci. Lett. | pmid:9654363 |
| Tarumi K et al. | The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation. | 1998 | Immunopharmacol Immunotoxicol | pmid:9653668 |
| Friberg H et al. | Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. | 1998 | J. Neurosci. | pmid:9651198 |
| Canzanello VJ et al. | Late hypertension after liver transplantation: a comparison of cyclosporine and tacrolimus (FK 506). | 1998 | Liver Transpl Surg | pmid:9649648 |