tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Ascites D001201 25 associated lipids
Ataxia D001259 20 associated lipids
Ataxia Telangiectasia D001260 6 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Autonomic Nervous System Diseases D001342 4 associated lipids
Bacterial Infections D001424 21 associated lipids
Balanitis D001446 4 associated lipids
Beckwith-Wiedemann Syndrome D001506 1 associated lipids
Behcet Syndrome D001528 7 associated lipids
Biliary Fistula D001658 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Summaries for patients. Multitarget therapy for induction treatment of lupus nephritis. 2015 Ann. Intern. Med. pmid:25383607
Farnik H et al. Telaprevir drug monitoring during antiviral therapy of hepatitis C graft infection after liver transplantation. 2015 Liver Int. pmid:24649882
Langone A et al. Switching STudy of Kidney TRansplant PAtients with Tremor to LCP-TacrO (STRATO): an open-label, multicenter, prospective phase 3b study. 2015 Clin Transplant pmid:26113208
Plock JA et al. Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells Prolong Graft Survival in Vascularized Composite Allotransplantation. 2015 Transplantation pmid:26102613
TuÄŸcu M et al. Tacrolimus-Induced Diabetic Ketoacidosis and Effect of Switching to Everolimus: A Case Report. 2015 Transplant. Proc. pmid:26093759
Castaneda J and Matzuk MM DEVELOPMENTAL BIOLOGY. Toward a rapid and reversible male pill. 2015 Science pmid:26494747
Carenco C et al. Incidence of solid organ cancers after liver transplantation: comparison with regional cancer incidence rates and risk factors. 2015 Liver Int. pmid:25488375
Yano S et al. Pharmacokinetics for once-daily modified release formulation of tacrolimus hydrate in unrelated hematopoietic stem cell transplantation. 2015 Ann. Hematol. pmid:25325985
Garcia C et al. Collaborative Brazilian Pediatric Renal Transplant Registry (CoBrazPed-RTx): A Report From 2004 to 2013. 2015 Transplant. Proc. pmid:26036492
Melo MJ et al. Impact of conversion from Advagraf to twice-daily generic tacrolimus in kidney transplant recipients: a single-center study. 2015 Transplant. Proc. pmid:26036484
Santos T et al. New Recipes With Known Ingredients: Combined Therapy of Everolimus and Low-dose Tacrolimus in De Novo Renal Allograft Recipients. 2015 Transplant. Proc. pmid:26036483
Miyata H et al. Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive. 2015 Science pmid:26429887
Liu Z et al. Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. 2015 Ann. Intern. Med. pmid:25383558
Meyer C et al. Impact of irradiation and immunosuppressive agents on immune system homeostasis in rhesus macaques. 2015 Clin. Exp. Immunol. pmid:25902927
Sassi MB et al. Involvement of CYP 3A5 In the Interaction Between Tacrolimus and Nicardipine: A Case Report. 2015 Curr Drug Saf pmid:25968921
Bifano M et al. An open-label investigation into drug-drug interactions between multiple doses of daclatasvir and single-dose cyclosporine or tacrolimus in healthy subjects. 2015 Clin Drug Investig pmid:25896946
Wang CY et al. Analysis of tacrolimus blood concentrations in renal transplant patients. 2015 Genet. Mol. Res. pmid:25966149
Caro J et al. Predictors of response and relapse in patients with idiopathic membranous nephropathy treated with tacrolimus. 2015 Nephrol. Dial. Transplant. pmid:25274748
Wang L et al. Benefits of minimizing immunosuppressive dosage according to cytochrome P450 3A5 genotype in liver transplant patients: findings from a single-center study. 2015 Genet. Mol. Res. pmid:25966085
Bedi M and Taylor AL Recalcitrant Hailey-Hailey disease responds to oral tacrolimus and botulinum toxin type A. 2015 Cutis pmid:26761940
Colak H et al. Relationship of Interleukin-10 and Transforming Growth Factor-β Levels With Short-Term Graft Function After Kidney Transplantation. 2015 Transplant. Proc. pmid:25964218
Kim YT et al. Co-treatment effect of pulsed electromagnetic field (PEMF) with human dental pulp stromal cells and FK506 on the regeneration of crush injured rat sciatic nerve. 2015 Int. J. Neurosci. pmid:25271799
Kogiso T et al. Mycophenolate mofetil may induce prolonged severe anemia during pegylated-interferon/ribavirin/simeprevir therapy in liver transplant recipients. 2015 Clin J Gastroenterol pmid:25963122
Antonini TM et al. Therapy with boceprevir or telaprevir in HIV/hepatitis C virus co-infected patients to treat recurrence of hepatitis C virus infection after liver transplantation. 2015 AIDS pmid:25387314
Tabchi S et al. Successful treatment of Evans syndrome with Tacrolimus. 2015 Invest New Drugs pmid:25209619
Papadopoulos-Köhn A et al. Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant. 2015 Transplantation pmid:25208324
Bae JM et al. Combination therapy with 308-nm excimer laser, topical tacrolimus, and short-term systemic corticosteroids for segmental vitiligo: A retrospective study of 159 patients. 2015 J. Am. Acad. Dermatol. pmid:25956660
Gallon L et al. Differential Effects of Calcineurin and Mammalian Target of Rapamycin Inhibitors on Alloreactive Th1, Th17, and Regulatory T Cells. 2015 Transplantation pmid:25905982
Weisenseel P and Reich K [Inverse psoriasis]. 2015 Hautarzt pmid:25896586
Ennaifer R et al. Nodular hyperplasia of the gastrointestinal tract after liver transplantation: role of immunosuppressive therapy? A case report. 2015 Transplant. Proc. pmid:25891739
Chen KH et al. De novo cancer avoidance after renal transplantation: A case-control study on low-dose sirolimus combined with a calcineurin inhibitor. 2015 J. Formos. Med. Assoc. pmid:25843527
Berro M et al. Allogeneic hematopoietic stem cell transplantation in the elderly. Predicting the risk for non relapse mortality. 2015 Medicina (B Aires) pmid:26339873
Gajzlerska W et al. Use of three-carbon chain compounds as biosynthesis precursors to enhance tacrolimus production in Streptomyces tsukubaensis. 2015 N Biotechnol pmid:25152525
Robertsen I et al. Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed. 2015 Transplantation pmid:25148382
Yu Z et al. IL-15 is decreased upon CsA and FK506 treatment of acute rejection following heart transplantation in mice. 2015 Mol Med Rep pmid:25333459
Malvezzi P and Rostaing L The safety of calcineurin inhibitors for kidney-transplant patients. 2015 Expert Opin Drug Saf pmid:26329325
Tajdaran K et al. A novel polymeric drug delivery system for localized and sustained release of tacrolimus (FK506). 2015 Biotechnol. Bioeng. pmid:25850693
Jacobo-Cabral CO et al. Population pharmacokinetic analysis of tacrolimus in Mexican paediatric renal transplant patients: role of CYP3A5 genotype and formulation. 2015 Br J Clin Pharmacol pmid:25846845
Wang L et al. Gq signaling causes glomerular injury by activating TRPC6. 2015 J. Clin. Invest. pmid:25844902
Legendre L et al. Risk of lymphoma in patients with atopic dermatitis and the role of topical treatment: A systematic review and meta-analysis. 2015 J. Am. Acad. Dermatol. pmid:25840730
Bowman LJ et al. Tacrolimus-Induced Cardiomyopathy in an Adult Renal Transplant Recipient. 2015 Pharmacotherapy pmid:26616582
Manuyakorn W et al. In vitro cytokine changes after pediatric liver transplantation. 2015 Asian Pac. J. Allergy Immunol. pmid:25840634
Miguel-Gómez L et al. [Peristomal pyoderma gangrenosum associated with colon cancer]. 2015 Med Clin (Barc) pmid:25659860
Aouam K et al. Influence of combined CYP3A4 and CYP3A5 single-nucleotide polymorphisms on tacrolimus exposure in kidney transplant recipients: a study according to the post-transplant phase. 2015 Pharmacogenomics pmid:26615671
Eaton KV et al. Engineering macrophages to control the inflammatory response and angiogenesis. 2015 Exp. Cell Res. pmid:26610863
Girdlestone J et al. Enhancement of the immunoregulatory potency of mesenchymal stromal cells by treatment with immunosuppressive drugs. 2015 Cytotherapy pmid:26276002
Ross A and Kirsner RS JID VisualDx Quiz: April 2015. 2015 J. Invest. Dermatol. pmid:25785952
Tavira B et al. ABCB1 (MDR-1) pharmacogenetics of tacrolimus in renal transplanted patients: a Next Generation Sequencing approach. 2015 Clin. Chem. Lab. Med. pmid:25781547
Burke MT et al. Expression of Bcl-xL and Mcl-1 in the nonmelanoma skin cancers of renal transplant recipients. 2015 Am. J. Clin. Pathol. pmid:25780003
Plischke M et al. Late Conversion of Kidney Transplant Recipients from Ciclosporin to Tacrolimus Improves Graft Function: Results from a Randomized Controlled Trial. 2015 PLoS ONE pmid:26270340
Nouchi A et al. [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. 2015 Ann Dermatol Venereol pmid:25778634
Diaz-Siso JR et al. Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation. 2015 Am. J. Transplant. pmid:25777324
Chen F et al. [Outcomes of allogeneic hematopoietic stem cell transplantation for 18 patients with paroxysmal nocturnal haemoglobinuria]. 2015 Zhonghua Xue Ye Xue Za Zhi pmid:26759101
Fan J et al. Donor IL-18 rs5744247 polymorphism as a new biomarker of tacrolimus elimination in Chinese liver transplant patients during the early post-transplantation period: results from two cohort studies. 2015 Pharmacogenomics pmid:25712187
Morales E et al. A case of thrombotic micro-angiopathy after heart transplantation successfully treated with eculizumab. 2015 Transpl. Int. pmid:25712140
Buschow SI et al. To target or not to target viral antigens in HBV related HCC? 2015 J. Hepatol. pmid:25711422
Qasim W et al. Reply to: "To target or not to target viral antigens in HBV related HCC?". 2015 J. Hepatol. pmid:25711420
Jia N et al. Collapsing focal segmental glomerulosclerosis following long-term treatment with oral ibandronate: case report and review of literature. 2015 BMC Cancer pmid:26197890
Kawano N et al. Successful Secondary Umbilical Cord Blood Transplantation for Graft Failure in Acute Myelogenous Leukemia, Treated with Modified One-Day Conditioning Regimen, and Graft-Versus-Host Disease Prophylaxis Consisting of Mycophenolate and Tacrolimus. 2015 J Clin Exp Hematop pmid:26490521
Li ZQ et al. Efficacy and safety of tacrolimus vs. cyclophosphamide for idiopathic membranous nephropathy: A meta-analysis of Chinese adults. 2015 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26489612
Pucci N et al. Tacrolimus vs. cyclosporine eyedrops in severe cyclosporine-resistant vernal keratoconjunctivitis: A randomized, comparative, double-blind, crossover study. 2015 Pediatr Allergy Immunol pmid:25712437
Badri P et al. Pharmacokinetics and dose recommendations for cyclosporine and tacrolimus when coadministered with ABT-450, ombitasvir, and dasabuvir. 2015 Am. J. Transplant. pmid:25708713
Kim KW et al. The effect of mammalian target of rapamycin inhibition on T helper type 17 and regulatory T cell differentiation in vitro and in vivo in kidney transplant recipients. 2015 Immunology pmid:24974886
Van der Perren A et al. FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an α-synuclein-based rat model for Parkinson's disease. 2015 Neurobiol. Aging pmid:25660193
Ayala E et al. Myeloablative intravenous pharmacokinetically targeted busulfan plus fludarabine as conditioning for allogeneic hematopoietic cell transplantation in patients with non-Hodgkin lymphoma. 2015 Clin Lymphoma Myeloma Leuk pmid:25659459
Stefanović NZ et al. Potential role of tacrolimus in erythrocytes' antioxidative capacity in long-term period after renal transplantation. 2015 Eur J Pharm Sci pmid:25657088
Park JH et al. Comparative study of tacrolimus and bevacizumab on corneal neovascularization in rabbits. 2015 Cornea pmid:25651492
Petruzzo P et al. Outcomes after bilateral hand allotransplantation: a risk/benefit ratio analysis. 2015 Ann. Surg. pmid:24646555
Polańska A et al. Monitoring of therapy in atopic dermatitis--observations with the use of high-frequency ultrasonography. 2015 Skin Res Technol pmid:24894324
Sahin G et al. Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy. 2015 Nephrology (Carlton) pmid:25650527
Uemoto S et al. Early coupled up-regulation of interleukin-12 receptor beta-1 in CD8+ central memory and effector T cells for better clinical outcomes in liver transplant recipients. 2015 Clin. Exp. Immunol. pmid:25603847
Oda K et al. In vitro-in vivo extrapolations to evaluate the effect of concomitant drugs on tacrolimus (FK506) exposure. 2015 Biopharm Drug Dispos pmid:25600613
Pérez-López I et al. Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. 2015 Actas Dermosifiliogr pmid:25597413
Kallscheuer N et al. Single-Domain Peptidyl-Prolyl cis/trans Isomerase FkpA from Corynebacterium glutamicum Improves the Biomass Yield at Increased Growth Temperatures. 2015 Appl. Environ. Microbiol. pmid:26341203
Niioka T et al. Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation. 2015 Int J Mol Sci pmid:25594874
Rojas-Vega L et al. Increased phosphorylation of the renal Na+-Cl- cotransporter in male kidney transplant recipient patients with hypertension: a prospective cohort. 2015 Am. J. Physiol. Renal Physiol. pmid:26336164
Sánchez-Lázaro I et al. Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation. 2015 Pharmacogenomics pmid:26107754
Ling Q et al. Donor PPARα Gene Polymorphisms Influence the Susceptibility to Glucose and Lipid Disorders in Liver Transplant Recipients: A Strobe-Compliant Observational Study. 2015 Medicine (Baltimore) pmid:26334901
Koch M et al. De novo mTOR inhibitor-based immunosuppression in ABO-incompatible kidney transplantation. 2015 Clin Transplant pmid:26333844
Graham F et al. Tacrolimus use in renal and cardiac pediatric transplantation: no increased risk of food allergies. 2015 Ann. Allergy Asthma Immunol. pmid:26094803
Teixeira Mdo C et al. Influence of post-transplant immunosuppressive therapy on gastrointestinal transit using biomagnetic method: a pilot study. 2015 Dig. Dis. Sci. pmid:25146844
Urquhart BL and Knauer MJ Dried blood spots for therapeutic drug monitoring of tacrolimus and sirolimus in pediatric patients. 2015 Pediatr Transplant pmid:25546506
Park J et al. Iron overload triggers mitochondrial fragmentation via calcineurin-sensitive signals in HT-22 hippocampal neuron cells. 2015 Toxicology pmid:26318285
Shi RZ et al. Rapid measurement of tacrolimus in whole blood by paper spray-tandem mass spectrometry (PS-MS/MS). 2015 Clin. Chim. Acta pmid:25540885
Coilly A et al. Once-daily prolonged release tacrolimus in liver transplantation: Experts' literature review and recommendations. 2015 Liver Transpl. pmid:26264233
Boluda ER Pediatric small bowel transplantation. 2015 Curr Opin Organ Transplant pmid:26262456
Minami-Hori M et al. Periorbital lupus profundus successfully treated with oral tacrolimus plus low-dose prednisolone. 2015 J. Dermatol. pmid:25544984
Pagliarello C et al. Calcipotriol/betamethasone dipropionate ointment compared with tacrolimus ointment for the treatment of erosive pustular dermatosis of the scalp: a split-lesion comparison. 2015 Eur J Dermatol pmid:25786341
Xing J et al. Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients. 2015 Eur. J. Clin. Pharmacol. pmid:25487141
van Boekel GA et al. Delayed trough level measurement with the use of prolonged-release tacrolimus. 2015 Transpl. Int. pmid:25474192
Muduma G et al. Evaluating the economic implications of non-adherence and antibody-mediated rejection in renal transplant recipients: the role of once-daily tacrolimus in the UK. 2015 J Med Econ pmid:26201252
Mizuno K et al. Dexamethasone but not tacrolimus suppresses TNF-α-induced thymic stromal lymphopoietin expression in lesional keratinocytes of atopic dermatitis model. 2015 J. Dermatol. Sci. pmid:26198442
Niioka T et al. Effects of CYP3A5 polymorphism and the tacrolimus 12 h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis. 2015 Xenobiotica pmid:26189776
Rathi M et al. Conversion from tacrolimus to cyclosporine in patients with new-onset diabetes after renal transplant: an open-label randomized prospective pilot study. 2015 Transplant. Proc. pmid:26036543
Gallagher HM et al. Erratic tacrolimus exposure, assessed using the standard deviation of trough blood levels, predicts chronic lung allograft dysfunction and survival. 2015 J. Heart Lung Transplant. pmid:26186804
Mohsin N et al. Pharmacokinetics of mycophenolate mofetil in Omani patients on cyclosporine or tacrolimus. 2015 Transplant. Proc. pmid:26036534
Li Y et al. Differential regulation of Tregs and Th17/Th1 cells by a sirolimus-based regimen might be dependent on STAT-signaling in renal transplant recipients. 2015 Int. Immunopharmacol. pmid:26186486
Toole B et al. Evaluation of the New Cyclosporine and Tacrolimus Automated Electrochemiluminescence Immunoassays under Field Conditions. 2015 Clin. Lab. pmid:26554251
Shen T et al. Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. 2015 World J. Gastroenterol. pmid:26034381
Cilião HL et al. Cytotoxic and genotoxic effects of high concentrations of the immunosuppressive drugs cyclosporine and tacrolimus in MRC-5 cells. 2015 Exp. Toxicol. Pathol. pmid:25541063