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First experience with extended release tacrolimus in the treatment of adult patients with severe, difficult to treat atopic dermatitis: Clinical efficacy, safety and dose finding. |
2016 |
J. Dermatol. Sci. |
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Gokhale NS |
Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm. |
2016 |
Indian J Ophthalmol |
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Development of a Simple and Rapid Method to Measure the Free Fraction of Tacrolimus in Plasma Using Ultrafiltration and LC-MS/MS. |
2016 |
Ther Drug Monit |
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GvHD prophylaxis with tacrolimus plus sirolimus after reduced intensity conditioning allogeneic transplantation: results of a multicenter study. |
2016 |
Bone Marrow Transplant. |
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Management of refractory autoimmune hemolytic anemia via allogeneic stem cell transplantation. |
2016 |
Bone Marrow Transplant. |
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Effects of Topical Tacrolimus and Polyunsaturated Fatty Acids on In Vivo Release of Eicosanoids in Atopic Dermatitis During Dermal Microdialysis. |
2016 |
Acta Derm. Venereol. |
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Tacrolimus Predose Concentration Is Associated With Hypertension in Pediatric Liver Transplant Recipients. |
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J. Pediatr. Gastroenterol. Nutr. |
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Indirect treatment comparison of belatacept versus tacrolimus from a systematic review of immunosuppressive therapies for kidney transplant patients. |
2016 |
Curr Med Res Opin |
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Acute encephalitis with refractory, repetitive partial seizures: Pathological findings and a new therapeutic approach using tacrolimus. |
2016 |
Brain Dev. |
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Tacrolimus restores podocyte injury and stabilizes the expression of Cabin1 in 5/6 nephrectomized rats. |
2016 |
Ren Fail |
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Trans-11 vaccenic acid improves insulin secretion in models of type 2 diabetes in vivo and in vitro. |
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Mol Nutr Food Res |
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Cell. Physiol. Biochem. |
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Development and validation of a sensitive and selective LC-MS/MS method for determination of tacrolimus in oral fluids. |
2016 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Within-Patient Variability in Tacrolimus Blood Levels Predicts Kidney Graft Loss and Donor-Specific Antibody Development. |
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Transplantation |
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The Ineffectiveness of Tacrolimus in an Infant With a Mutation in the IL-10 Receptor. |
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J. Clin. Gastroenterol. |
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A preliminary study searching for the right dose of tacrolimus in very young (≤4 years) renal transplant patients. |
2016 |
J. Pharm. Pharmacol. |
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Immunosuppressive Medications and Squamous Cell Skin Carcinoma: Nested Case-Control Study Within the Skin Cancer after Organ Transplant (SCOT) Cohort. |
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Am. J. Transplant. |
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Malignancies in transplanted patients: Multidisciplinary evaluation and switch to mTOR inhibitors after kidney transplantation - experiences from a prospective, clinical, observational study. |
2016 |
Acta Oncol |
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Biochem. Biophys. Res. Commun. |
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Hyaluronic acid-coated niosomes facilitate tacrolimus ocular delivery: Mucoadhesion, precorneal retention, aqueous humor pharmacokinetics, and transcorneal permeability. |
2016 |
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Comparison of the therapeutic efficacy and safety between tacrolimus and infliximab for moderate-to-severe ulcerative colitis: a single center experience. |
2016 |
Scand. J. Gastroenterol. |
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Therapeutic Effect of 0.1% Topical Tacrolimus for Childhood Interstitial Keratitis Refractory to Cyclosporine. |
2016 |
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Impact of Tacrolimus Compared With Cyclosporin on the Incidence of Acute Allograft Rejection in Human Immunodeficiency Virus-Positive Kidney Transplant Recipients. |
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Transplantation |
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The impact of CYP3A5 on the metabolism of cyclosporine A and tacrolimus in the evaluation of efficiency and safety of immunosuppressive treatment in patients after kidney transplantation. |
2016 |
Pharmazie |
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Transpl. Immunol. |
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Successful use of infliximab and tacrolimus combination therapy in a patient with ulcerative colitis refractory to infliximab dose intensification plus azathioprine. |
2016 |
Int J Clin Pharmacol Ther |
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Annular Lichenoid Dermatitis of Youth: A Chronic Case Managed Using Pimecrolimus. |
2016 |
Pediatr Dermatol |
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Sci Rep |
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Crystal structure of the FK506 binding domain of human FKBP25 in complex with FK506. |
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Protein Sci. |
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Chimeric Allografts Induced by Short-Term Treatment With Stem Cell-Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: A Study in Rats. |
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Am. J. Transplant. |
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Chimeric Allografts Induced by Short-Term Treatment With Stem Cell Mobilizing Agents Result in Long-Term Kidney Transplant Survival Without Immunosuppression: II, Study in Miniature Swine. |
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Am. J. Transplant. |
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Quantitative analysis of tissue inflammation and responses to treatment in immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome, and review of literature. |
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J Microbiol Immunol Infect |
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Vitamin D status and the effects of oral vitamin D treatment in children with vitiligo: A prospective study. |
2016 |
Clin Nutr ESPEN |
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Repigmentation of poliosis in a patient with segmental vitiligo. |
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J. Am. Acad. Dermatol. |
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Analytical Validation and Cross-Validation of an NFAT-Regulated Gene Expression Assay for Pharmacodynamic Monitoring of Therapy With Calcineurin Inhibitors. |
2016 |
Ther Drug Monit |
pmid:27661400
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Comparative clinical evaluation of tacrolimus and cyclosporine eye drops for the treatment of canine keratoconjunctivitis sicca. |
2016 |
Acta Vet. Hung. |
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Conversion to Once-Daily Tacrolimus Results in Increased p38MAPK Phosphorylation in T Lymphocytes of Kidney Transplant Recipients. |
2016 |
Ther Drug Monit |
pmid:26606072
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STAT3 degradation mediated by calcineurin involved in the neurotoxicity of isoflurane. |
2016 |
Neuroreport |
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Higher tacrolimus concentrations early after transplant reduce the risk of acute GvHD in reduced-intensity allogeneic stem cell transplantation. |
2016 |
Bone Marrow Transplant. |
pmid:26691423
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Nanocomposite microparticles (nCmP) for the delivery of tacrolimus in the treatment of pulmonary arterial hypertension. |
2016 |
Int J Pharm |
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Clotrimazole troches induce supratherapeutic blood levels of sirolimus and tacrolimus in an allogeneic hematopoietic cell-transplant recipient resulting in acute kidney injury. |
2016 |
Hematol Oncol Stem Cell Ther |
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Tacrolimus for children with refractory nephrotic syndrome: a one-year prospective, multicenter, and open-label study of Tacrobell®, a generic formula. |
2016 |
World J Pediatr |
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The POR rs1057868-rs2868177 GC-GT diplotype is associated with high tacrolimus concentrations in early post-renal transplant recipients. |
2016 |
Acta Pharmacol. Sin. |
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Delayed, Uncommon Recurrence of Hepatocellular Carcinoma After Liver Transplantation: A Case Report. |
2016 |
Transplant. Proc. |
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Tacrolimus Metabolite M-III May Have Nephrotoxic and Myelotoxic Effects and Increase the Incidence of Infections in Kidney Transplant Recipients. |
2016 |
Transplant. Proc. |
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High Frequency of Arterial Hypertension in Patients After Liver Transplantation. |
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Transplant. Proc. |
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Effects of Immunosuppressive Drugs on Serum Fatty Acids of Phospholipids Fraction in Renal Transplant Recipients. |
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Transplant. Proc. |
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Congenital Infections in Neonates of Women With Liver or Kidney Transplants. |
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Lowering of Messenger Ribonucleic Acid Toll-Like Receptors 2-4,9 in Peripheral Blood Mononuclear Cells in Kidney Allograft Recipients, Relationships With Immunosuppressive Treatment, and Delayed Graft Function Occurrence. |
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Transplant. Proc. |
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The Dynamic Role of the IL-33/ST2 Axis in Chronic Viral-infections: Alarming and Adjuvanting the Immune Response. |
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EBioMedicine |
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Repair of Neurological Function in Response to FK506 Through CaN/NFATc1 Pathway Following Traumatic Brain Injury in Rats. |
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Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes. |
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Umbilical cord blood transplantation for adults using tacrolimus with two-day very-short-term methotrexate for graft-versus-host disease prophylaxis. |
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Leuk. Res. |
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Betamethasone, but Not Tacrolimus, Suppresses the Development of Th2 Cells Mediated by Langerhans Cell-Like Dendritic Cells. |
2016 |
Biol. Pharm. Bull. |
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Pilot Study to Evaluate the Efficacy and Safety of Oral Tacrolimus in Adult Patients With Refractory Severe Plaque Psoriasis. |
2016 |
J Cutan Med Surg |
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Transforming growth factor β-related genes in human retinal pigment epithelial cells after tacrolimus treatment. |
2016 |
Pharmacol Rep |
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Lipid profile and cardiovascular risk factors in pediatric liver transplant recipients. |
2016 |
Pediatr Transplant |
pmid:26750745
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Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform. |
2016 |
Sci Transl Med |
pmid:27053773
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Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds. |
2016 |
J. Med. Chem. |
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Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles. |
2016 |
Am. J. Transplant. |
pmid:26485092
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CYP3A pharmacogenetics and tacrolimus disposition in adult heart transplant recipients. |
2016 |
Clin Transplant |
pmid:27314545
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Effects of tacrolimus and erythropoietin in experimental spinal cord lesion in rats: functional and histological evaluation. |
2016 |
Spinal Cord |
pmid:26481712
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Cysteamine in renal transplantation: A report of two patients with nephropathic cystinosis and the successful re-initiation of cysteamine therapy during the immediate post-transplant period. |
2016 |
Pediatr Transplant |
pmid:26477696
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Activation of TRPV2 negatively regulates the differentiation of mouse brown adipocytes. |
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Pflugers Arch. |
pmid:27318696
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Evaluation of the Waters MassTrak LC-MS/MS Assay for Tacrolimus and a Comparison to the Abbott Architect Immunoassay. |
2016 |
Ther Drug Monit |
pmid:26473523
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The influence of the tumor necrosis factor-alpa-308G>A polymorphism on the efficacy of immunosuppressive therapy in patients after kidney transplantation. |
2016 |
J. Physiol. Pharmacol. |
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A 45-Year-Old Woman With 3 Weeks of Cough and Night Sweats. |
2016 |
Chest |
pmid:26965979
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Population Pharmacokinetic Approach of Immunosuppressive Therapy in Kidney Transplant Patients. |
2016 |
Curr. Med. Chem. |
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Comparison of Cystatin C and NGAL in Early Diagnosis of Acute Kidney Injury After Heart Transplantation. |
2016 |
Ann. Transplant. |
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Effects of Genetic Polymorphism in CYP3A4 and CYP3A5 Genes on Tacrolimus Dose Among Kidney Transplant Recipients. |
2016 |
Iran J Kidney Dis |
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Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity. |
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J Neuroinflammation |
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Analytical evaluation of a real-time PCR-based DNA demethylation assay to assess the frequency of naturally occurring regulatory T cells in peripheral blood. |
2016 |
Clin. Biochem. |
pmid:27220060
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Pharmacokinetics of prolonged-release tacrolimus and implications for use in solid organ transplant recipients. |
2016 |
Clin Transplant |
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The calcineruin inhibitor cyclosporine a synergistically enhances the susceptibility of Candida albicans biofilms to fluconazole by multiple mechanisms. |
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BMC Microbiol. |
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Effects of CYP3A5 polymorphism on the pharmacokinetics of a once-daily modified-release tacrolimus formulation and acute kidney injury in hematopoietic stem cell transplantation. |
2016 |
Cancer Chemother. Pharmacol. |
pmid:27217047
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Narain S and Furie R |
Update on clinical trials in systemic lupus erythematosus. |
2016 |
Curr Opin Rheumatol |
pmid:27314466
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Tremblay S et al. |
Absence of the Effect of Pretransplant Body Mass Index on Post Kidney Transplant Outcomes. |
2016 |
Prog Transplant |
pmid:27207408
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Effect of the knockdown of Cabin1 on p53 in glomerular podocyte. |
2016 |
J. Recept. Signal Transduct. Res. |
pmid:26400065
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Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients. |
2016 |
Ther Drug Monit |
pmid:27310200
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Badri PS et al. |
Pharmacokinetics of Tacrolimus and Cyclosporine in Liver Transplant Recipients Receiving 3 Direct-Acting Antivirals as Treatment for Hepatitis C Infection. |
2016 |
Ther Drug Monit |
pmid:27310199
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Laharie D and Poullenot F |
Letter: which patient profile for tacrolimus in ulcerative colitis? |
2016 |
Aliment. Pharmacol. Ther. |
pmid:27137730
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Targeted Delivery of Immunomodulators to Lymph Nodes. |
2016 |
Cell Rep |
pmid:27134176
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Topical tacrolimus 0.03% for the treatment of ocular psoriasis. |
2016 |
Arch Soc Esp Oftalmol |
pmid:27130870
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Stifft F et al. |
Effect of Breakfast on the Exposure of the Once-Daily Tacrolimus Formulation in Stable Kidney Transplant Recipients. |
2016 |
Ther Drug Monit |
pmid:27128604
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Influence of Absorption, Distribution, Metabolism, and Excretion Genomic Variants on Tacrolimus/Sirolimus Blood Levels and Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation. |
2016 |
Biol. Blood Marrow Transplant. |
pmid:26325438
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[Removal of senescent cells: towards a better future?] |
2016 |
Med Sci (Paris) |
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Evaluation of renal functions in pediatric liver transplantation. |
2016 |
Pediatr Transplant |
pmid:26607307
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Posterior reversible encephalopathy syndrome after kidney transplantation in pediatric recipients: Two cases. |
2016 |
Pediatr Transplant |
pmid:26607205
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A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro. |
2016 |
J. Am. Soc. Nephrol. |
pmid:26260164
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Jung H and Oh ES |
FK506 positively regulates the migratory potential of melanocyte-derived cells by enhancing syndecan-2 expression. |
2016 |
Pigment Cell Melanoma Res |
pmid:27060922
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Controlled Delivery of FK506 to Improve Nerve Regeneration. |
2016 |
Shock |
pmid:27058050
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Wang YY et al. |
Characterization of Discrete Phosphopantetheinyl Transferases in Streptomyces tsukubaensis L19 Unveils a Complicate Phosphopantetheinylation Network. |
2016 |
Sci Rep |
pmid:27052100
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Enhanced dissolution and oral absorption of tacrolimus by supersaturable self-emulsifying drug delivery system. |
2016 |
Int J Nanomedicine |
pmid:27051286
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Cyclosporine A and tacrolimus inhibit urothelial tumorigenesis. |
2016 |
Mol. Carcinog. |
pmid:25594762
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Factors Associated With Changes in Body Composition Shortly After Orthotopic Liver Transplantation: The Potential Influence of Immunosuppressive Agents. |
2016 |
Transplantation |
pmid:27136260
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New-Onset Diabetes After Kidney Transplantation and Pretransplant Hypomagnesemia. |
2016 |
Prog Transplant |
pmid:27136250
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Graft-versus-Host Disease Prophylaxis in Unrelated Peripheral Blood Stem Cell Transplantation with Post-Transplantation Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil. |
2016 |
Biol. Blood Marrow Transplant. |
pmid:26970381
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Lee WS et al. |
Efficacy and safety of low-dose tacrolimus for active rheumatoid arthritis with an inadequate response to methotrexate. |
2016 |
Korean J. Intern. Med. |
pmid:26961485
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