Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fukushima A et al. | Therapeutic effects of 0.1% tacrolimus eye drops for refractory allergic ocular diseases with proliferative lesion or corneal involvement. | 2014 | Br J Ophthalmol | pmid:24695688 |
Yasukochi Y et al. | Reduction of serum TARC levels in atopic dermatitis by topical anti-inflammatory treatments. | 2014 | Asian Pac. J. Allergy Immunol. | pmid:25268342 |
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Donnadieu B et al. | Central retinal vein occlusion-associated tacrolimus after liver transplantation. | 2014 | Transplantation | pmid:25955343 |
Arduino PG et al. | Pimecrolimus vs. tacrolimus for the topical treatment of unresponsive oral erosive lichen planus: a 8 week randomized double-blind controlled study. | 2014 | J Eur Acad Dermatol Venereol | pmid:23451852 |
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Guy-Viterbo V et al. | Influence of donor-recipient CYP3A4/5 genotypes, age and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach. | 2014 | Pharmacogenomics | pmid:25141896 |
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Chen SR et al. | Calcineurin inhibitor induces pain hypersensitivity by potentiating pre- and postsynaptic NMDA receptor activity in spinal cords. | 2014 | J. Physiol. (Lond.) | pmid:24081160 |
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Matin M et al. | The effectiveness of excimer laser on vitiligo treatment in comparison with a combination therapy of Excimer laser and tacrolimus in an Iranian population. | 2014 | J Cosmet Laser Ther | pmid:25046236 |
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Ikeuchi H et al. | Efficacy and safety of multi-target therapy using a combination of tacrolimus, mycophenolate mofetil and a steroid in patients with active lupus nephritis. | 2014 | Mod Rheumatol | pmid:24252014 |
Bax K et al. | Rapid resolution of tacrolimus intoxication-induced AKI with a corticosteroid and phenytoin. | 2014 | Ann Pharmacother | pmid:25104567 |
Miyauchi T et al. | Evidence for the therapeutic efficacy of either mild hypothermia or oxygen radical scavengers after repetitive mild traumatic brain injury. | 2014 | J. Neurotrauma | pmid:24341607 |
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Madian AG et al. | Case report: Inability to achieve a therapeutic dose of tacrolimus in a pediatric allogeneic stem cell transplant patient after generic substitution. | 2014 | BMC Pharmacol Toxicol | pmid:25472557 |
Huang W et al. | Tacrolimus (FK506) suppresses TREM-1 expression at an early but not at a late stage in a murine model of fungal keratitis. | 2014 | PLoS ONE | pmid:25464008 |
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Chen C et al. | Rapid construction of a Bacterial Artificial Chromosomal (BAC) expression vector using designer DNA fragments. | 2014 | Plasmid | pmid:25454071 |
Olson KA et al. | Toxic tacrolimus levels after application of topical tacrolimus and use of occlusive dressings in two bone marrow transplant recipients with cutaneous graft-versus-host disease. | 2014 | Pharmacotherapy | pmid:24700567 |
Momohara S et al. | Recent trends in orthopedic surgery aiming to improve quality of life for those with rheumatoid arthritis: data from a large observational cohort. | 2014 | J. Rheumatol. | pmid:24692532 |
Lee SK et al. | Overexpression of the putative extracytoplasmic function sigma (σ) factor FujE enhances FK506 production in Streptomyces sp. strain KCCM 11116P. | 2014 | Can. J. Microbiol. | pmid:24869633 |
Navas-López VM et al. | Successful treatment for ulcerative proctitis with rectal tacrolimus in an 8-year-old girl with intolerance to mesalamine. | 2014 | Clin J Gastroenterol | pmid:26185880 |
van der Vusse ML et al. | Helicobacter canis bacteremia in a renal transplant patient. | 2014 | Transpl Infect Dis | pmid:24372779 |
Földes G et al. | Immunosuppressive agents modulate function, growth, and survival of cardiomyocytes and endothelial cells derived from human embryonic stem cells. | 2014 | Stem Cells Dev. | pmid:24192059 |
Lee CH et al. | Raised tacrolimus level and acute renal injury associated with acute gastroenteritis in a child receiving local rectal tacrolimus. | 2014 | Clin J Gastroenterol | pmid:26183743 |