Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Abu Zaid M et al. | Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT. | 2017 | Blood | pmid:27827824 |
Choi SW et al. | Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT. | 2017 | Blood | pmid:28784598 |
Kurzawski M et al. | Analysis of common polymorphisms within NR1I2 and NR1I3 genes and tacrolimus dose-adjusted concentration in stable kidney transplant recipients. | 2017 | Pharmacogenet. Genomics | pmid:28777242 |
Willerth SM | Localized Tacrolimus Delivery Repairs the Damaged Central Nervous System. | 2017 | EBioMedicine | pmid:29195745 |
Martial LC et al. | Dried Blood Spot Sampling for Tacrolimus and Mycophenolic Acid in Children: Analytical and Clinical Validation. | 2017 | Ther Drug Monit | pmid:28700522 |
Riva N et al. | Pharmacoepidemiology of tacrolimus in pediatric liver transplantation. | 2017 | Pediatr Transplant | pmid:28574195 |
Donati M et al. | Resolution of Benign and Malignant Sebaceous Neoplasms, in a Renal Transplant Patient Treated With Everolimus. | 2017 | Exp Clin Transplant | pmid:25924010 |
Zong YP et al. | Effects of CYP3A5 polymorphisms on tacrolimus pharmacokinetics in pediatric kidney transplantation: a systematic review and meta-analysis of observational studies. | 2017 | World J Pediatr | pmid:28540692 |
Ciftci HS et al. | Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism. | 2017 | Transplant. Proc. | pmid:28340819 |
Rodrigues N et al. | Serum Magnesium and Related Factors in Long-Term Renal Transplant Recipients: An Observational Study. | 2017 | Transplant. Proc. | pmid:28457398 |
Guttman-Yassky E et al. | Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis. | 2017 | J. Allergy Clin. Immunol. | pmid:28238742 |
Kanai T et al. | Adequate tacrolimus concentration for myasthenia gravis treatment. | 2017 | Eur. J. Neurol. | pmid:28102047 |
Sarier M et al. | HPV type 45-positive condyloma acuminata of the bladder in a renal transplant recipient. | 2017 | Transpl Infect Dis | pmid:28100036 |
Hanchanale P et al. | Nocardia liver abscess post liver transplantation-A rare presentation. | 2017 | Transpl Infect Dis | pmid:28150374 |
Cukor D et al. | A Pilot Randomized Controlled Trial to Promote Immunosuppressant Adherence in Adult Kidney Transplant Recipients. | 2017 | Nephron | pmid:28049201 |
Baskiran A et al. | Pregnancy After Liver Transplantation: Risks and Outcomes. | 2017 | Transplant. Proc. | pmid:28923640 |
Shi G et al. | Variation of CD4CD25Foxp3 Regulatory T Cells and Th17 Cells in the Peripheral Blood of Human Liver Allograft Patients With Long-term Survival. | 2017 | Transplant. Proc. | pmid:28923634 |
Hosoi K et al. | Prolonged tacrolimus for pediatric gastrointestinal disorder: Double-edged sword? | 2017 | Pediatr Int | pmid:27935231 |
Parrow NL and Fleming RE | Releasing the FKBP12 brake on hepcidin. | 2017 | Blood | pmid:29122771 |
Esquirol A et al. | Single-agent GvHD prophylaxis with tacrolimus after post-transplant high-dose cyclophosphamide is a valid option for haploidentical transplantation in adults with hematological malignancies. | 2017 | Bone Marrow Transplant. | pmid:28604667 |