Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Watanabe K et al. | Prolongation effect of FK506 on the survival of 3-day preserved kidney allografts in dogs. | 1998 | Transplant. Proc. | pmid:9838579 |
Yamauchi M et al. | Effects of FK506 on rat thymic microenvironment in thymocyte maturation, proliferation, and mobilization. | 1998 | Transplant. Proc. | pmid:9838578 |
Yura H et al. | Development of a macromolecular prodrug of FK506: I. Synthesis of FK506-dextran conjugate. | 1998 | Transplant. Proc. | pmid:9838577 |
Jeong HJ et al. | Vascular endothelin, TGF-beta, and PDGF expression in FK506 nephrotoxicity of rats. | 1998 | Transplant. Proc. | pmid:9838576 |
Goh BL and Tan SY | FK506 "rescue" therapy complicated by renal tubular acidosis in renal allograft recipients. | 1998 | Transplant. Proc. | pmid:9838575 |
Goh BL et al. | FK506 rescue therapy for acute renal allograft rejection. | 1998 | Transplant. Proc. | pmid:9838574 |
Cheng HM et al. | Primary prophylaxis with tacrolimus in kidney transplants in China. | 1998 | Transplant. Proc. | pmid:9838573 |
Hung CM et al. | Tacrolimus to rescue refractory hepatic allograft rejection: a collaborative study in Taiwan. | 1998 | Transplant. Proc. | pmid:9838572 |
Lo CM et al. | Use of FK506 as primary or rescue therapy after liver transplantation in Hong Kong. | 1998 | Transplant. Proc. | pmid:9838571 |
Shu KH et al. | A multicenter trial of FK506 as rescue therapy for renal transplant recipients in Taiwan. | 1998 | Transplant. Proc. | pmid:9838570 |