Bishop DK and Li W |
Cyclosporin A and FK506 mediate differential effects on T cell activation in vivo. |
1992 |
J. Immunol. |
pmid:1371128
|
Hatfield SM and Roehm NW |
Cyclosporine and FK506 inhibition of murine mast cell cytokine production. |
1992 |
J. Pharmacol. Exp. Ther. |
pmid:1371158
|
Wijnen RM et al. |
Toxicology of FK506 in the cynomolgus monkey: a clinical, biochemical, and histopathological study. |
1992 |
Transpl. Int. |
pmid:14621844
|
Jiang H et al. |
Control of humoral and cellular immunity-mediated accelerated heart allograft rejection in sensitized rats by low dose FK 506 and splenectomy. |
1992 |
Transpl. Int. |
pmid:14621859
|
Kobayashi N et al. |
Abdominal organ cluster transplantation in pigs and FK506. |
1992 |
Transpl. Int. |
pmid:14621861
|
Vincent SH et al. |
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism. |
1992 |
Arch. Biochem. Biophys. |
pmid:1373595
|
Liu J et al. |
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. |
1992 |
Biochemistry |
pmid:1373650
|
Adachi A et al. |
Immunosuppressive effect of FK506 on experimental allergic neuritis in Lewis rats: change of T cell subsets. |
1992 |
Intern. Med. |
pmid:1373661
|
de Paulis A et al. |
Anti-inflammatory effect of FK-506 on human skin mast cells. |
1992 |
J. Invest. Dermatol. |
pmid:1281861
|
Tze WJ et al. |
FK 506--an effective immunosuppressant in achieving long-term functional islet allograft survival in diabetic rats. |
1992 |
Transplant. Proc. |
pmid:1376509
|
Yasunami Y et al. |
Induction of donor-specific unresponsiveness in rat islet allografts by FK 506. |
1992 |
Transplant. Proc. |
pmid:1376510
|
Kai N et al. |
A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. |
1992 |
Transplant. Proc. |
pmid:1376511
|
Barry JM |
Immunosuppressive drugs in renal transplantation. A review of the regimens. |
1992 |
Drugs |
pmid:1281071
|
Stiff DD et al. |
Metabolism of FK 506 in differentially induced rat liver microsomes. |
1992 |
Res. Commun. Chem. Pathol. Pharmacol. |
pmid:1281332
|
Murthy JN et al. |
Radioreceptor assay for quantifying FK-506 immunosuppressant in whole blood. |
1992 |
Clin. Chem. |
pmid:1377995
|
Takai K et al. |
Effects of FK506 on rat thymic epithelial cells; immunohistochemical study. |
1992 |
Thymus |
pmid:1378235
|
Dutz JP et al. |
Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. |
1992 |
Int. Immunol. |
pmid:1378297
|
First MR |
Renal transplantation for the nephrologist: new immunosuppressive drugs. |
1992 |
Am. J. Kidney Dis. |
pmid:1371201
|
Aperia A et al. |
Calcineurin mediates alpha-adrenergic stimulation of Na+,K(+)-ATPase activity in renal tubule cells. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380157
|
Nielsen JB et al. |
Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380159
|
Calvo V et al. |
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. |
1992 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1380162
|
Hendey B et al. |
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. |
1992 |
Science |
pmid:1384129
|
Roberti I et al. |
Evidence that the systematic analysis of bile cytology permits monitoring of hepatic allograft rejection. |
1992 |
Transplantation |
pmid:1384182
|
Jordan ML et al. |
Initial studies with FK506 in renal transplantation. |
1991 Sep-Oct |
Cleve Clin J Med |
pmid:1718631
|
Christians U et al. |
High performance liquid chromatography/mass spectrometry of FK 506 and its metabolites in blood, bile, and urine of liver grafted patients. |
1991 |
Transplant. Proc. |
pmid:1721262
|
Beysens AJ et al. |
FK 506: monitoring in plasma or in whole blood? |
1991 |
Transplant. Proc. |
pmid:1721263
|
Grenier FC et al. |
A whole blood FK 506 assay for the IMx analyzer. |
1991 |
Transplant. Proc. |
pmid:1721264
|
Friob MC et al. |
A combined HPLC-ELISA evaluation of FK 506 in transplant patients. |
1991 |
Transplant. Proc. |
pmid:1721265
|
Machida M et al. |
Effect of temperature and hematocrit on plasma concentration of FK 506. |
1991 |
Transplant. Proc. |
pmid:1721266
|
Kawauchi M et al. |
Plasma level of FK 506 in newborn goats and infant baboons. |
1991 |
Transplant. Proc. |
pmid:1721267
|
Ullman KS et al. |
Site of action of cyclosporine and FK 506 in the pathways of communication between the T-lymphocyte antigen receptor and the early activation genes. |
1991 |
Transplant. Proc. |
pmid:1721294
|
Sigal NH et al. |
Is FKBP involved in the immunosuppressive and/or toxic mechanism of action of FK 506? |
1991 |
Transplant. Proc. |
pmid:1721295
|
Bierer BE et al. |
FK 506 and rapamycin: molecular probes of T-lymphocyte activation. |
1991 |
Transplant. Proc. |
pmid:1721296
|
Tanida I et al. |
Yeast cyclophilin-related gene encodes a nonessential second peptidyl-prolyl cis-trans isomerase associated with the secretory pathway. |
1991 |
Transplant. Proc. |
pmid:1721297
|
O'Neill EA et al. |
The FK 506-sensitive nature of the interleukin-2 promoter is derived from a specific array of multiple regulatory elements. |
1991 |
Transplant. Proc. |
pmid:1721298
|
Nelson PA et al. |
Effect of immunosuppressive drugs on cytokine gene transcription studied by message amplification phenotyping (MAPPing) polymerase chain reaction. |
1991 |
Transplant. Proc. |
pmid:1721299
|
Cooper MH et al. |
Evaluation of the influence of FK 506, rapamycin, and cyclosporine on processing and presentation of particulate antigen by macrophages: assessment of a drug "carry-over" effect. |
1991 |
Transplant. Proc. |
pmid:1721326
|
Didlake R and Grogan J |
Effect of FK 506 on rat leukocyte chemotaxis. |
1991 |
Transplant. Proc. |
pmid:1721327
|
Hultsch T and Hohman RJ |
Categorizing receptor-signaling pathways with FK 506 and rapamycin. |
1991 |
Transplant. Proc. |
pmid:1721328
|
Takai K et al. |
Immunosuppressive effects of FK 506 on rat lymphoid organs. |
1991 |
Transplant. Proc. |
pmid:1721329
|
Ishibashi M et al. |
Effect of FK 506 on generation of activated macrophages invading rejected skin allografts in rats: discrepancy of in vitro versus in vivo effects. |
1991 |
Transplant. Proc. |
pmid:1721330
|
Kawauchi M et al. |
Flow cytometric analysis of lymphocyte populations in FK 506-treated newborn goats. |
1991 |
Transplant. Proc. |
pmid:1721331
|
de Paulis A et al. |
Characterization of the anti-inflammatory effect of FK-506 on human mast cells. |
1991 |
J. Immunol. |
pmid:1721644
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in adult cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721358
|
Nalesnik MA et al. |
Lymphoproliferative disorders arising under immunosuppression with FK 506: initial observations in a large transplant population. |
1991 |
Transplant. Proc. |
pmid:1703335
|
Armitage JM et al. |
The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721359
|
Armitage JM et al. |
A clinical trial of FK 506 as primary and rescue immunosuppression in cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1703336
|
Dew MA et al. |
Quality-of-life advantages of FK 506 vs conventional immunosuppressive drug therapy in cardiac transplantation. |
1991 |
Transplant. Proc. |
pmid:1721360
|
Gordon RD et al. |
Liver transplantation under cyclosporine: a decade of experience. |
1991 |
Transplant. Proc. |
pmid:1703339
|
Shapiro R et al. |
FK 506 in clinical kidney transplantation. |
1991 |
Transplant. Proc. |
pmid:1721361
|
Todo S et al. |
One hundred ten consecutive primary orthotopic liver transplants under FK 506 in adults. |
1991 |
Transplant. Proc. |
pmid:1703340
|
McCauley J et al. |
Renal transplantation under FK 506 in patients with previous loss of renal function due to hemolytic uremic syndrome. |
1991 |
Transplant. Proc. |
pmid:1721362
|
Zeevi A et al. |
Correlation between bioassayed plasma levels of FK 506 and lymphocyte growth from liver transplant biopsies with histological evidence of rejection. |
1991 |
Transplant. Proc. |
pmid:1703341
|
|
Japanese study of FK 506 on kidney transplantation: results of an early phase II study. Japanese FK 506 Study Group. |
1991 |
Transplant. Proc. |
pmid:1721363
|
van Hoek B et al. |
Recurrence of ductopenic rejection in liver allografts after retransplantation for vanishing bile duct syndrome. |
1991 |
Transplant. Proc. |
pmid:1703343
|
Tze WJ et al. |
Effect of FK 506 on glucose metabolism and insulin secretion in normal rats. |
1991 |
Transplant. Proc. |
pmid:1721391
|
Doi R et al. |
Mechanisms by which FK 506 affects exocrine pancreas in rats. |
1991 |
Transplant. Proc. |
pmid:1721392
|
Rilo HL et al. |
Effect of FK 506 on function of human islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1721393
|
Carroll PB et al. |
Synexin: a target protein for toxic effects of cyclosporine and FK 506 in endocrine cells. |
1991 |
Transplant. Proc. |
pmid:1721394
|
Scantlebury V et al. |
New onset of diabetes in FK 506 vs cyclosporine-treated kidney transplant recipients. |
1991 |
Transplant. Proc. |
pmid:1721395
|
Carroll PB et al. |
FK 506-associated diabetes mellitus in the pediatric transplant population is a rare complication. |
1991 |
Transplant. Proc. |
pmid:1721396
|
Cooper MH et al. |
Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506. |
1991 |
Transplant. Proc. |
pmid:1721421
|
Yoshimi F et al. |
Canine total orthotopic small bowel transplantation under FK 506. |
1991 |
Transplant. Proc. |
pmid:1721422
|
Heitman J et al. |
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1705713
|
Santiago SF et al. |
Effect of donor pretreatment with FK 506 upon small intestine allotransplantation in rats. |
1991 |
Transplant. Proc. |
pmid:1721423
|
Murase N et al. |
Lymphocyte traffic and graft-versus-host disease after fully allogeneic small bowel transplantation. |
1991 |
Transplant. Proc. |
pmid:1721424
|
Goebl MG |
The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C. |
1991 |
Cell |
pmid:1706222
|
Langrehr JM et al. |
Indefinite small bowel allograft survival after limited immunosuppressive therapy is not due to specific hyporesponsiveness. |
1991 |
Transplant. Proc. |
pmid:1721425
|
de Paulis A et al. |
FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells. |
1991 |
J. Immunol. |
pmid:1706398
|
Takeda Y et al. |
Effect of FK 506 on the survival of rat small bowel allografts. |
1991 |
Transplant. Proc. |
pmid:1721426
|
Griffiths EJ and Halestrap AP |
Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin. |
1991 |
Biochem. J. |
pmid:1706598
|
Fukuzawa M et al. |
Effect of donor-specific transfusion and FK 506 on small intestine allotransplantation. |
1991 |
Transplant. Proc. |
pmid:1721427
|
Sainsbury TS et al. |
Differential effects of FK 506 and cyclosporine on hair regrowth in the DEBR model of alopecia areata. |
1991 |
Transplant. Proc. |
pmid:1721453
|
Fujino Y et al. |
FK 506 treatment of experimental autoimmune uveoretinitis in primates. |
1991 |
Transplant. Proc. |
pmid:1721454
|
Francavilla A et al. |
Studies on mechanisms of augmentation of liver regeneration by cyclosporine and FK 506. |
1991 |
Hepatology |
pmid:1712337
|
Liversidge J et al. |
FK 506 modulates accessory cell adhesion molecule expression and inhibits CD4 lymphocyte adhesion to retinal pigment epithelial cells in vitro: implications for therapy of uveoretinitis. |
1991 |
Transplant. Proc. |
pmid:1721455
|
Aoki H |
[FK 506, a new immunosuppressant produced by a Streptomyces]. |
1991 |
Nippon Rinsho |
pmid:1712403
|
Mochizuki M et al. |
A multicenter clinical open trial of FK 506 in refractory uveitis, including Behçet's disease. Japanese FK 506 Study Group on Refractory Uveitis. |
1991 |
Transplant. Proc. |
pmid:1721456
|
Hultsch T et al. |
Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. |
1991 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1712484
|
Roat MI et al. |
Treatment of Cogan's syndrome with FK 506: a case report. |
1991 |
Transplant. Proc. |
pmid:1721457
|
Miyahara H et al. |
Comparative studies of the effects of FK506 and cyclosporin A on passively transferred collagen-induced arthritis in rats. |
1991 |
Clin. Immunol. Immunopathol. |
pmid:1712688
|
Carroll PB et al. |
The use of FK 506 in new-onset type I diabetes in man. |
1991 |
Transplant. Proc. |
pmid:1721458
|
McAlpine JB et al. |
Revised NMR assignments for rapamycin. |
1991 |
J. Antibiot. |
pmid:1712766
|
Banerji SS et al. |
The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. |
1991 |
Mol. Cell. Biol. |
pmid:1712901
|
Markus PM et al. |
FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats. |
1991 |
Surgery |
pmid:1713358
|
Miyagawa S et al. |
Mechanism of unresponsiveness in rats induced by a short course of FK 506 or CyA. |
1991 |
Transplant. Proc. |
pmid:1703687
|
DeFranco AL |
Signal transduction. Immunosuppressants at work. |
1991 |
Nature |
pmid:1715515
|
Carroll PB et al. |
Effect of the immunosuppressant FK 506 on insulin release from adult rat islets of Langerhans. |
1991 |
Transplant. Proc. |
pmid:1703688
|
Flanagan WM et al. |
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. |
1991 |
Nature |
pmid:1715516
|
Fujino Y et al. |
FK506 treatment of S-antigen induced uveitis in primates. |
1991 |
Curr. Eye Res. |
pmid:1717199
|
Sakr MF et al. |
Protective effect of FK 506 against hepatic ischemia in rats. |
1991 |
Transplant. Proc. |
pmid:1703689
|
McWhinnie DL and Morris PJ |
Combination drug therapies for immunosuppression in transplantation. |
1991 |
Ann. Acad. Med. Singap. |
pmid:1724724
|
Katayama Y et al. |
Immunosuppressive effects of FK 506 and 15-deoxyspergualin in rat lung transplantation. |
1991 |
Transplant. Proc. |
pmid:1703690
|
Pourtier-Manzanedo A et al. |
FK-506 (fujimycin) reverses the multidrug resistance of tumor cells in vitro. |
1991 |
Anticancer Drugs |
pmid:1724925
|
Thomson AW |
The immunosuppressive macrolides FK-506 and rapamycin. |
1991 |
Immunol. Lett. |
pmid:1717376
|
Takaya S et al. |
Positive crossmatch in primary human liver allografts under cyclosporine or FK 506 therapy. |
1991 |
Transplant. Proc. |
pmid:1703691
|
Nakahama H et al. |
Comparative effects of cyclosporine A and FK-506 on endothelin secretion by a cultured renal cell line, LLC-PK1. |
1991 |
J. Cardiovasc. Pharmacol. |
pmid:1725322
|
Steeves M et al. |
In-vitro interaction of a novel immunosuppressant, FK 506, and antacids. |
1991 |
J. Pharm. Pharmacol. |
pmid:1717676
|
Hildebrandt A et al. |
FK 506: short- and long-term treatment after cardiac transplantation in nonhuman primates. |
1991 |
Transplant. Proc. |
pmid:1703694
|
Romanowski P et al. |
[Synthetic immunomodulators designed on the basis of natural products of microorganisms]. |
1991 |
Postepy Biochem. |
pmid:1725924
|