tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Primary Graft Dysfunction D055031 1 associated lipids
Esophageal Perforation D004939 1 associated lipids
Epididymitis D004823 1 associated lipids
Pruritus Vulvae D011539 1 associated lipids
Central Serous Chorioretinopathy D056833 1 associated lipids
Migraine with Aura D020325 1 associated lipids
Porokeratosis D017499 1 associated lipids
Lentigo D007911 1 associated lipids
Mutism D009155 1 associated lipids
Amyloid Neuropathies D017772 1 associated lipids
Cervical Intraepithelial Neoplasia D018290 1 associated lipids
Malocclusion, Angle Class II D008312 1 associated lipids
Flaviviridae Infections D018178 1 associated lipids
Idiopathic Interstitial Pneumonias D054988 1 associated lipids
Dysuria D053159 1 associated lipids
Denys-Drash Syndrome D030321 1 associated lipids
Akinetic Mutism D000405 1 associated lipids
Sleep Apnea, Central D020182 1 associated lipids
Orchitis D009920 1 associated lipids
Phyllodes Tumor D003557 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

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Authors Title Published Journal PubMed Link
Fisher NC Renal failure after lung transplantation. 1998 Lancet pmid:9800782
Garcia-Criado FJ et al. Possible tacrolimus action mechanisms in its protector effects on ischemia-reperfusion injury. 1998 Transplantation pmid:9798713
Sankary HN et al. FK506 treatment in combination with leflunomide in hamster-to-rat heart and liver xenograft transplantation. 1998 Transplantation pmid:9798690
Whitcup SM et al. Topical liposome-encapsulated FK506 for the treatment of endotoxin-induced uveitis. 1998 Ocul. Immunol. Inflamm. pmid:9798194
Schaefer A et al. Stimulation of the Ca2+-mediated egr-1 and c-fos expression in murine erythroleukaemia cells by cyclosporin A. 1998 Biochem. J. pmid:9794788
Kobayashi M et al. Effects of FK506 on experimental membranous glomerulonephritis induced by cationized bovine serum albumin in rats. 1998 Nephrol. Dial. Transplant. pmid:9794552
Hashimoto Y et al. Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats. 1998 Pharm. Res. pmid:9794505
Sengoku T et al. [Effects of tacrolimus ointment on type I (immediate and late) and IV (delayed) cutaneous allergic reactions in mice]. 1998 Nippon Yakurigaku Zasshi pmid:9793077
Toshima K et al. Effect of FK506 on the activation state of hepatic macrophages in Propionibacterium acnes-treated rats. 1998 J. Gastroenterol. Hepatol. pmid:9792034
Casavilla FA et al. Clinical outcome of patients infected with hepatitis C virus infection on survival after primary liver transplantation under tacrolimus. 1998 Liver Transpl Surg pmid:9791154
Ohye H et al. Effects of immunosuppressant agents on growth hormone release and gene expression. 1998 Endocr. J. pmid:9790238
Bajaj-Elliott M et al. Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. 1998 J. Clin. Invest. pmid:9788959
Masugi T and Otsuka K [Immunosuppressive drugs and calcineurin]. 1998 Tanpakushitsu Kakusan Koso pmid:9788176
Heering P et al. Distal tubular acidosis induced by FK506. 1998 Clin Transplant pmid:9787958
Wu A et al. Outcome of 22 successful pregnancies after liver transplantation. 1998 Clin Transplant pmid:9787957
Peddi VR et al. Use of tacrolimus eliminates acute rejection as a major complication following simultaneous kidney and pancreas transplantation. 1998 Clin Transplant pmid:9787948
Rayes N et al. Pregnancies following liver transplantation--how safe are they? A report of 19 cases under cyclosporine A and tacrolimus. 1998 Clin Transplant pmid:9787947
Nishida T et al. [FK506 for the prophylaxis of graft-versus-host-disease after bone marrow transplantation from HLA-genotypically mismatched unrelated donor]. 1998 Rinsho Ketsueki pmid:9785975
Maestri M et al. [Treatment of the nephrotoxicity of immunosuppressive drugs with insulin-like growth factor-I]. 1998 Minerva Chir pmid:9780630
Motamedi H and Shafiee A The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. 1998 Eur. J. Biochem. pmid:9780228