tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Hypersensitivity D006967 22 associated lipids
Osteosarcoma D012516 50 associated lipids
Acne Vulgaris D000152 35 associated lipids
Urination Disorders D014555 9 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Anemia, Hemolytic D000743 4 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Vision Disorders D014786 10 associated lipids
Multiple Myeloma D009101 13 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
Melanoma D008545 69 associated lipids
Hematologic Diseases D006402 3 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Osteoporosis D010024 12 associated lipids
Anemia, Aplastic D000741 6 associated lipids
Kidney Diseases D007674 29 associated lipids
Hematuria D006417 13 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Kato K et al. Modulation of long-term potentiation induction in the hippocampus by N-methyl-D-aspartate-mediated presynaptic inhibition. 1999 Neuroscience pmid:10426482
Pirenne J Contribution of large animal models to the development of clinical intestinal transplantation. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427786
Jamieson NV Adult small intestinal transplantation in Europe. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427790
Kahan BD An immunosuppressive triumvirate to minimize renal injuries associated with calcineurin antagonist therapy. 1999 Transplantation pmid:10428260
Reichenspurner H et al. Optimization of the immunosuppressive protocol after lung transplantation. 1999 Transplantation pmid:10428269
Soccal PM et al. Improvement of drug-induced chronic renal failure in lung transplantation. 1999 Transplantation pmid:10428288
Levy GA Neoral/cyclosporine-based immunosuppression. 1999 Liver Transpl Surg pmid:10431016
Pollock R and Rivera VM Regulation of gene expression with synthetic dimerizers. 1999 Meth. Enzymol. pmid:10432459
Shinkura N et al. Autoantibodies to FK506 binding protein 12 (FKBP12) in autoimmune diseases. 1999 Autoimmunity pmid:10433096
Briggs WA et al. Lymphocyte suppression by rolipram with other immunosuppressive drugs. 1999 J Clin Pharmacol pmid:10434230
Harikrishnan P and Harden PN Tacrolimus can resolve cyclosporin-induced gingival hyperplasia. 1999 Nephrol. Dial. Transplant. pmid:10435907
Tsuji Y et al. Effects of cyclosporin A, FK506 and steroid hormones on hair growth. 1999 Exp. Dermatol. pmid:10439282
Sheikh AM et al. Concomitant human immunodeficiency virus protease inhibitor therapy markedly reduces tacrolimus metabolism and increases blood levels. 1999 Transplantation pmid:10440408
Moxey-Mims MM Increased incidence of insulin-dependent diabetes mellitus in pediatric renal transplant patients receiving tacrolimus (FK506) 1999 Transplantation pmid:10440413
Magee CC et al. Nocardial infection in a renal transplant recipient on tacrolimus and mycophenolate mofetil. 1999 Clin. Nephrol. pmid:10442495
Kur F et al. Tacrolimus (FK506) as primary immunosuppressant after lung transplantation. 1999 Thorac Cardiovasc Surg pmid:10443520
Uchiyama H et al. Approach to withdrawal from tacrolimus in a fully allogeneic murine skin graft model. 1999 Immunology pmid:10447745
Volbracht C et al. ATP controls neuronal apoptosis triggered by microtubule breakdown or potassium deprivation. 1999 Mol. Med. pmid:10449809
Goulet MT et al. C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study. 1999 Bioorg. Med. Chem. Lett. pmid:10450986
Armstrong HM et al. Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity. 1999 Bioorg. Med. Chem. Lett. pmid:10450987