tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu L et al. | New insights of subfertility among transplanted women: Immunosuppressive drug FK506 leads to calcium leak and oocyte activation before fertilization. | 2018 | J. Cell. Biochem. | pmid:29131377 |
| Kojima CA et al. | Sirolimus Associated with Tacrolimus at Low Doses in Elderly Kidney Transplant Patients: A Prospective Randomized Controlled Trial. | 2018 | Exp Clin Transplant | pmid:28836934 |
| Lee WS et al. | Tacrolimus regulates endoplasmic reticulum stress-mediated osteoclastogenesis and inflammation: In vitro and collagen-induced arthritis mouse model. | 2018 | Cell Biol. Int. | pmid:28833755 |
| Quintero J et al. | Conversion from twice-daily to once-daily tacrolimus formulation in pediatric liver transplant recipients - a long-term prospective study. | 2018 | Transpl. Int. | pmid:28833714 |
| Kandula P et al. | Plantar ulcerative lichen planus: rapid improvement with a novel triple-therapy approach. | 2018 | Cutis | pmid:30235362 |
| Jiang JW et al. | Optimal immunosuppressor induces stable gut microbiota after liver transplantation. | 2018 | World J. Gastroenterol. | pmid:30228781 |
| Gu B et al. | Exploration of Fecal Microbiota Transplantation in the Treatment of Refractory Diarrhea After Renal Transplantation. | 2018 | Transplant. Proc. | pmid:29880353 |
| Lee H et al. | Thymoglobulin Versus Basiliximab Induction Therapy in Low-Risk Kidney Transplant Recipients: A Single-Center Experience. | 2018 | Transplant. Proc. | pmid:29880348 |
| Krogstad V et al. | Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies. | 2018 | Ther Drug Monit | pmid:29578937 |
| Marquet P et al. | Pharmacokinetic Therapeutic Drug Monitoring of Advagraf in More Than 500 Adult Renal Transplant Patients, Using an Expert System Online. | 2018 | Ther Drug Monit | pmid:29505493 |
| Ma D et al. | Manipulating the expression of SARP family regulator BulZ and its target gene product to increase tacrolimus production. | 2018 | Appl. Microbiol. Biotechnol. | pmid:29666890 |
| Ichinose K et al. | The efficacy of adjunct tacrolimus treatment in pregnancy outcomes in patients with systemic lupus erythematosus. | 2018 | Lupus | pmid:29665758 |
| Mei S et al. | Simultaneous determination of cyclosporine and tacrolimus in human whole blood by ultra-high performance liquid chromatography tandem mass spectrometry and comparison with a chemiluminescence microparticle immunoassay. | 2018 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:29704799 |
| Stanton BZ et al. | Chemically induced proximity in biology and medicine. | 2018 | Science | pmid:29590011 |
| Okada K et al. | EBV-positive PEL-like lymphoma that developed in the course of antisynthetase syndrome treated with tacrolimus. | 2018 | Int. J. Hematol. | pmid:29516290 |
| Sano H et al. | T-cell-replete haploidentical stem cell transplantation using low-dose antithymocyte globulin in children with relapsed or refractory acute leukemia. | 2018 | Int. J. Hematol. | pmid:29508228 |
| Takeuchi T et al. | Post-marketing surveillance study of the long-term use of mizoribine for the treatment of lupus nephritis: 2-Year results. | 2018 | Mod Rheumatol | pmid:28722500 |
| Jin L et al. | Effect of Conversion to CTLA4Ig on Tacrolimus-Induced Diabetic Rats. | 2018 | Transplantation | pmid:29319618 |
| Oetting WS et al. | Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients. | 2018 | Pharmacogenomics | pmid:29318894 |
| Rayar M et al. | High Intrapatient Variability of Tacrolimus Exposure in the Early Period After Liver Transplantation Is Associated With Poorer Outcomes. | 2018 | Transplantation | pmid:29315140 |