tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Granulomatosis, Orofacial D051261 2 associated lipids
Nail Diseases D009260 2 associated lipids
Dental Pulp Calcification D003784 2 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Venous Insufficiency D014689 2 associated lipids
Cytomegalovirus Retinitis D017726 2 associated lipids
Telangiectasis D013684 2 associated lipids
Still's Disease, Adult-Onset D016706 2 associated lipids
IgA Deficiency D017098 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Delayed Graft Function D051799 2 associated lipids
Uterine Cervical Dysplasia D002578 2 associated lipids
Hypopigmentation D017496 2 associated lipids
Incontinentia Pigmenti D007184 2 associated lipids
Vitiligo D014820 2 associated lipids
Tumor Lysis Syndrome D015275 2 associated lipids
Rectal Fistula D012003 2 associated lipids
Hidradenitis Suppurativa D017497 2 associated lipids
Eye Infections, Fungal D015821 2 associated lipids
Collagen Diseases D003095 2 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Cholecystolithiasis D041761 2 associated lipids
Brachial Plexus Neuritis D020968 2 associated lipids
Molluscum Contagiosum D008976 2 associated lipids
Pruritus Ani D011538 2 associated lipids
Deglutition Disorders D003680 2 associated lipids
Discitis D015299 2 associated lipids
Fox-Fordyce Disease D005588 2 associated lipids
Vestibular Diseases D015837 2 associated lipids
Myxedema D009230 2 associated lipids
Coccidioidomycosis D003047 2 associated lipids
Ileal Neoplasms D007078 2 associated lipids
Lichen Planus, Oral D017676 2 associated lipids
Lymphomatoid Granulomatosis D008230 2 associated lipids
Paresis D010291 2 associated lipids
Angiofibroma D018322 2 associated lipids
Tuberous Sclerosis D014402 2 associated lipids
Necrobiosis Lipoidica D009335 2 associated lipids
Mediastinitis D008480 2 associated lipids
Immunoblastic Lymphadenopathy D007119 2 associated lipids
Churg-Strauss Syndrome D015267 2 associated lipids
Mucinoses D017520 2 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Oliguria D009846 2 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Fibroadenoma D018226 2 associated lipids
Intracranial Thrombosis D020767 2 associated lipids
Labyrinthitis D007762 2 associated lipids
Paraproteinemias D010265 2 associated lipids
Amputation, Traumatic D000673 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Varela E [Small bowel transplantation]. 1995 Acta Gastroenterol. Latinoam. pmid:7544939
Pirenne J Contribution of large animal models to the development of clinical intestinal transplantation. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427786
Jamieson NV Adult small intestinal transplantation in Europe. 1999 Apr-Jun Acta Gastroenterol. Belg. pmid:10427790
Bonaccorsi-Riani E et al. Impact of steroid-avoidance immunosuppression on long-term outcome after liver transplantation for HCV cirrhosis: the need for well documented long-term follow-up. 2012 Acta Gastroenterol. Belg. pmid:23402084
Reding R et al. Stepwise minimization of the immunosuppressive therapy in pediatric liver transplantation. A conceptual approach towards operational tolerance. 2005 Jul-Sep Acta Gastroenterol. Belg. pmid:16268418
Sato M et al. FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. 1993 Acta Endocrinol. pmid:7509103
Polastri L et al. Secretory defects induced by immunosuppressive agents on human pancreatic beta-cells. 2002 Acta Diabetol pmid:12486498
Persić-Vojinović S et al. Disseminated Hailey-Hailey disease treated with topical tacrolimus and oral erythromycin: Case report and review of the literature. 2006 Acta Dermatovenerol Croat pmid:17311740
Louvain D et al. Lichen sclerosus in the oral mucosa: a rare form of presentation. 2012 Acta Dermatovenerol Croat pmid:22507475
Lipozencić J Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. 2005 Acta Dermatovenerol Croat pmid:15788149
Pustisek N et al. Tacrolimus ointment: a new therapy for atopic dermatitis--review of the literature. 2002 Acta Dermatovenerol Croat pmid:12137728
Jedlicková H et al. Granuloma faciale successfully treated with topical tacrolimus: a case report. 2008 Acta Dermatovenerol Alp Pannonica Adriat pmid:18454269
Thaçi D and Salgo R The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. 2007 Acta Dermatovenerol Alp Pannonica Adriat pmid:17992459
Vukićević J et al. Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. 2009 Acta Dermatovenerol Alp Pannonica Adriat pmid:19350187
de la Rosa Carrillo D and Christensen OB Treatment of chronic discoid lupus erythematosus with topical tacrolimus. 2004 Acta Derm. Venereol. pmid:15202845
Masuda K et al. Increased levels of serum interleukin-16 in adult type atopic dermatitis. 2003 Acta Derm. Venereol. pmid:12926794
Yamamoto T and Nishioka K Deep dermatophytosis during topical tacrolimus therapy for psoriasis. 2003 Acta Derm. Venereol. pmid:12926803
Sand C Topical tacrolimus ointment may induce skin tags in treated patients. 2003 Acta Derm. Venereol. pmid:12926817
Park SW et al. Topical tacrolimus (FK506): treatment failure in four cases of alopecia universalis. 2002 Acta Derm. Venereol. pmid:12430746
Mrowietz U et al. An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. 2003 Acta Derm. Venereol. pmid:14609102