tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Haas M et al. | Smooth muscle-specific actin levels in the urine of renal transplant recipients: correlation with cyclosporine or tacrolimus nephrotoxicity. | 1999 | Am. J. Kidney Dis. | pmid:10401019 |
| Katayama Y | [Current tendency in treatment for acute ischemic stroke]. | 1999 | Nippon Ika Daigaku Zasshi | pmid:10401232 |
| Tada H et al. | Role of diltiazem on tacrolimus pharmacokinetics in tacrolimus-induced nephrotoxic rats. | 1999 | Pharmacol. Toxicol. | pmid:10401724 |
| Timmermann W et al. | Videomicroscopic imaging of graft mucosa for monitoring immunosuppressive therapy after small intestinal transplantation in rats. | 1999 | Transplantation | pmid:10401762 |
| Banerjee C et al. | Ca2+ and calmodulin-dependent protein phosphatase from Leishmania donovani. | 1999 | Parasitology | pmid:10406035 |
| Kaibori M et al. | Immunosuppressant FK506 inhibits inducible nitric oxide synthase gene expression at a step of NF-kappaB activation in rat hepatocytes. | 1999 | J. Hepatol. | pmid:10406194 |
| Hebert MF and Lam AY | Diltiazem increases tacrolimus concentrations. | 1999 | Ann Pharmacother | pmid:10410178 |
| Rhew JH et al. | Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts. | 1999 | Exp. Mol. Med. | pmid:10410305 |
| Muegge I et al. | Evaluation of PMF scoring in docking weak ligands to the FK506 binding protein. | 1999 | J. Med. Chem. | pmid:10411471 |
| Varghese Z et al. | Calcineurin inhibitors enhance low-density lipoprotein oxidation in transplant patients. | 1999 | Kidney Int. Suppl. | pmid:10412758 |
| Przepiorka D et al. | Tacrolimus for prevention of graft-versus-host disease after mismatched unrelated donor cord blood transplantation. | 1999 | Bone Marrow Transplant. | pmid:10414918 |
| Bavetta S et al. | The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration. | 1999 | Exp. Neurol. | pmid:10415144 |
| Kuroda S et al. | The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats. | 1999 | Brain Res. | pmid:10415369 |
| Finn WF | FK506 nephrotoxicity. | 1999 May-Jul | Ren Fail | pmid:10416209 |
| Min DI et al. | Sudden hearing loss associated with tacrolimus in a kidney-pancreas allograft recipient. | 1999 | Pharmacotherapy | pmid:10417040 |
| Mrowietz U | Macrolide immunosuppressants. | 1999 Jul-Aug | Eur J Dermatol | pmid:10417434 |
| Remitz A et al. | Tacrolimus ointment improves psoriasis in a microplaque assay. | 1999 | Br. J. Dermatol. | pmid:10417522 |
| Dalvit C et al. | Use of organic solvents and small molecules for locating binding sites on proteins in solutions. | 1999 | J. Biomol. NMR | pmid:10419292 |
| Dunn SE et al. | Calcineurin is required for skeletal muscle hypertrophy. | 1999 | J. Biol. Chem. | pmid:10419511 |
| Becker JW et al. | 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. | 1999 | J. Med. Chem. | pmid:10425089 |