tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kaushik P et al. | Miller fisher variant of guillain-barre syndrome requiring a cardiac pacemaker in a patient on tacrolimus after liver transplantation. | 2005 | Ann Pharmacother | pmid:15855240 |
| Page RL et al. | Potential elevation of tacrolimus trough concentrations with concomitant metronidazole therapy. | 2005 | Ann Pharmacother | pmid:15855244 |
| Nezami BG et al. | Pharmacologic preconditioning of random-pattern skin flap in rats using local cyclosporine and FK-506: interaction with nitric oxide system. | 2007 | Ann Plast Surg | pmid:17901737 |
| Jensen JN et al. | Effect of FK506 on peripheral nerve regeneration through long grafts in inbred swine. | 2005 | Ann Plast Surg | pmid:15785285 |
| Diaz LM et al. | The role of topically administered FK506 (tacrolimus) at the time of facial nerve repair using entubulation neurorrhaphy in a rabbit model. | 2004 | Ann Plast Surg | pmid:15084888 |
| Ueno T et al. | Evaluation of osteogenic/chondrogenic cellular proliferation and differentiation in the xenogeneic periosteal graft. | 2002 | Ann Plast Surg | pmid:11981197 |
| Büttemeyer R et al. | Peripheral nerve allograft transplantation with FK506: functional, histological, and immunological results before and after discontinuation of immunosuppression. | 1995 | Ann Plast Surg | pmid:8585683 |
| Cetinkale O et al. | Involvement of neutrophils in ischemic injury. I. Biochemical and histopathological investigation of the effect of FK506 on dorsal skin flaps in rats. | 1997 | Ann Plast Surg | pmid:9374148 |
| Terzis JK and Konofaos P | Low-dose FK506 after contralateral C7 transfer to the musculocutaneous nerve using two different tubes: a study in rats. | 2010 | Ann Plast Surg | pmid:20395813 |
| Chu FC et al. | Oral health status, oral microflora, and non-surgical periodontal treatment of renal transplant patients receiving cyclosporin A and FK506. | 2000 | Ann R Australas Coll Dent Surg | pmid:11709958 |
| Cole O et al. | The effect of different immunosuppressants on alloantigen dependent and independent factors involved in the development of chronic rejection in an animal model. | 2001 | Ann R Coll Surg Engl | pmid:11518369 |
| Calmus Y | [Rejection of a liver allograft. Diagnosis and treatment]. | 1994 | Ann Radiol (Paris) | pmid:7527621 |
| Lim SM and White DJ | The pharmacology of immunosuppression. | 1991 | Ann. Acad. Med. Singap. | pmid:1709344 |
| Woo KT | Current therapeutic strategies in glomerulonephritis. | 1999 | Ann. Acad. Med. Singap. | pmid:10497681 |
| McWhinnie DL and Morris PJ | Combination drug therapies for immunosuppression in transplantation. | 1991 | Ann. Acad. Med. Singap. | pmid:1724724 |
| Kanchongkittiphon W et al. | Child with atopic dermatitis. | 2015 | Ann. Allergy Asthma Immunol. | pmid:25528736 |
| Lin SJ et al. | Effect of FK506 on the interleukin 15-driven proliferation and apoptosis of anti-CD3-activated umbilical cord blood T cells. | 2005 | Ann. Allergy Asthma Immunol. | pmid:16400900 |
| Matsuo N et al. | Tacrolimus inhibits cytokine production and chemical mediator release following antigen stimulation of passively sensitized human lung tissues. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11428741 |
| Fonacier L et al. | The black box warning for topical calcineurin inhibitors: looking outside the box. | 2006 | Ann. Allergy Asthma Immunol. | pmid:16892793 |
| Talreja N et al. | Successful desensitization to agalsidase beta after anaphylaxis. | 2014 | Ann. Allergy Asthma Immunol. | pmid:24331397 |
| Leonardi S et al. | Intense tacrolimus ointment therapy in children with serious atopic eczema dermatitis syndrome. | 2009 | Ann. Allergy Asthma Immunol. | pmid:19663137 |
| Knight AK et al. | Alcohol-induced rash caused by topical tacrolimus. | 2005 | Ann. Allergy Asthma Immunol. | pmid:16200821 |
| Amrol D et al. | Topical pimecrolimus in the treatment of human allergic contact dermatitis. | 2003 | Ann. Allergy Asthma Immunol. | pmid:14700441 |
| Hung SH et al. | Staphylococcus colonization in atopic dermatitis treated with fluticasone or tacrolimus with or without antibiotics. | 2007 | Ann. Allergy Asthma Immunol. | pmid:17225720 |
| Graham F et al. | Tacrolimus use in renal and cardiac pediatric transplantation: no increased risk of food allergies. | 2015 | Ann. Allergy Asthma Immunol. | pmid:26094803 |
| Letko E et al. | Tacrolimus (FK 506). | 1999 | Ann. Allergy Asthma Immunol. | pmid:10507260 |
| Yargui L and Berhoune A | [The EMIT Tacrolimus assay: development of application protocol for Roche Hitachi 902 analyzer]. | 2008 Nov-Dec | Ann. Biol. Clin. (Paris) | pmid:19091665 |
| Hinchliffe E et al. | Therapeutic drug monitoring of ciclosporin A and tacrolimus in heart lung transplant patients using dried blood spots. | 2014 | Ann. Clin. Biochem. | pmid:23939194 |
| Stephen DW et al. | Evaluation of the Dade Behring Syva EMIT 2000 tacrolimus assay on the Bayer Advia 1650. | 2003 | Ann. Clin. Biochem. | pmid:14629812 |
| Keevil BG et al. | Liquid chromatography-mass spectrometry measurement of tacrolimus in finger-prick samples compared with venous whole blood samples. | 2009 | Ann. Clin. Biochem. | pmid:19151171 |
| Keevil BG et al. | Evaluation of a rapid micro-scale assay for tacrolimus by liquid chromatography-tandem mass spectrometry. | 2002 | Ann. Clin. Biochem. | pmid:12227855 |
| Trull AK | Therapeutic monitoring of tacrolimus. | 1998 | Ann. Clin. Biochem. | pmid:9547889 |
| Cannon RD et al. | Clinical efficacy of the Abbott Tacrolimus II assay for the IMx. | 1999 Oct-Dec | Ann. Clin. Lab. Sci. | pmid:10528829 |
| Dasgupta A et al. | Analytical Performance Evaluation of a New Cobas Tacrolimus Assay on Cobas e411 Analyzer: Comparison of Values Obtained by the CMIA Tacrolimus Assay and a Liquid Chromatography Combined with Tandem Mass Spectrometric Method. | 2016 | Ann. Clin. Lab. Sci. | pmid:27098629 |
| Yano S et al. | Pharmacokinetics for once-daily modified release formulation of tacrolimus hydrate in unrelated hematopoietic stem cell transplantation. | 2015 | Ann. Hematol. | pmid:25325985 |
| Mori A et al. | Fatal cerebral hemorrhage associated with cyclosporin-A/FK506-related encephalopathy after allogeneic bone marrow transplantation. | 2000 | Ann. Hematol. | pmid:11100753 |
| Nasu R et al. | Favorable outcomes of tacrolimus compared with cyclosporine A for GVHD prophylaxis in HSCT for standard-risk hematological diseases. | 2014 | Ann. Hematol. | pmid:24590535 |
| Mizuno H et al. | Extranodal NK/T cell lymphoma in a living donor liver transplant recipient. | 2017 | Ann. Hematol. | pmid:28280996 |
| Imataki O et al. | Reversible cerebral vasoconstriction syndrome resulted in cerebral infarction after allogeneic stem cell transplantation: a case report. | 2014 | Ann. Hematol. | pmid:24061786 |
| Moiseev IS et al. | Pharmacokinetic comparison of cyclosporin A and tacrolimus in graft-versus-host disease prophylaxis. | 2017 | Ann. Hematol. | pmid:28343273 |
| Uni M et al. | Successful allogeneic stem cell transplantation for Lennert lymphoma. | 2013 | Ann. Hematol. | pmid:23224245 |
| Watanabe M et al. | Successful treatment of calcineurin inhibitor-induced pain syndrome with acute graft versus host disease by switching calcineurin inhibitors followed by pregabalin. | 2017 | Ann. Hematol. | pmid:28508935 |
| Zhu X et al. | Enhancing and suppressive effects of immunosuppressants cyclosporin A, FK506, and KM2210 on the colony formation of murine bone marrow cells. | 1995 | Ann. Hematol. | pmid:8534762 |
| Summaries for patients. Multitarget therapy for induction treatment of lupus nephritis. | 2015 | Ann. Intern. Med. | pmid:25383607 | |
| Liu Z et al. | Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. | 2015 | Ann. Intern. Med. | pmid:25383558 |
| Kawai T et al. | FK506-induced autoimmune diabetes. | 2000 | Ann. Intern. Med. | pmid:10733461 |
| D'Incà R et al. | Tacrolimus to treat pyoderma gangrenosum resistant to cyclosporine. | 1998 | Ann. Intern. Med. | pmid:9556483 |
| Cotton D | Celebrating the ACP centennial: from the Annals archive. | 2015 | Ann. Intern. Med. | pmid:25560715 |
| Abu-Elmagd K et al. | Resolution of severe pyoderma gangrenosum in a patient with streaking leukocyte factor disease after treatment with tacrolimus (FK 506). | 1993 | Ann. Intern. Med. | pmid:7689802 |
| Donners MM et al. | Inflammation and restenosis: implications for therapy. | 2003 | Ann. Med. | pmid:14649334 |