Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dury S et al. | Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study. | 2015 | BMC Pulm Med | pmid:26545860 |
Obayashi N et al. | Management of tacrolimus-associated food allergy after liver transplantation. | 2015 | Pediatr Int | pmid:26541649 |
Kwon M et al. | Bioequivalence of tacrolimus formulations with different dynamic solubility and in-vitro dissolution profiles. | 2015 | Arch. Pharm. Res. | pmid:24627339 |
TuÄŸcu M et al. | Tacrolimus-Induced Diabetic Ketoacidosis and Effect of Switching to Everolimus: A Case Report. | 2015 | Transplant. Proc. | pmid:26093759 |
Tang T et al. | Roles of the tacrolimus-dependent transcription factor IRF4 in acute rejection after liver transplantation. | 2015 | Int. Immunopharmacol. | pmid:26093273 |
Aktürk S et al. | Pregnancy After Kidney Transplantation: Outcomes, Tacrolimus Doses, and Trough Levels. | 2015 | Transplant. Proc. | pmid:26093738 |
Rahman S et al. | Nordihydroguiaretic acid attenuates skin tumorigenesis in Swiss albino mice with the condition of topical co-administration of an immunosuppressant. | 2015 | Chem. Biol. Interact. | pmid:25770929 |
Rossetto AM et al. | The full electron structure of the FKBP12/FK506 complex. | 2015 | J. Biomol. Struct. Dyn. | pmid:24471694 |
Santos T et al. | New Recipes With Known Ingredients: Combined Therapy of Everolimus and Low-dose Tacrolimus in De Novo Renal Allograft Recipients. | 2015 | Transplant. Proc. | pmid:26036483 |
Li DW et al. | Risk factors for new onset diabetes mellitus after liver transplantation: A meta-analysis. | 2015 | World J. Gastroenterol. | pmid:26034369 |
Miura M et al. | Tacrolimus reduction with everolimus addition for calcineurin inhibitor-induced arteriolopathy in kidney allografts. | 2015 | Nephrology (Carlton) | pmid:26031588 |
Ma R et al. | FK506 ameliorates podocyte injury in type 2 diabetic nephropathy by down-regulating TRPC6 and NFAT expression. | 2015 | Int J Clin Exp Pathol | pmid:26823720 |
Yagisawa T et al. | Arteriosclerosis in zero-time biopsy is a risk factor for tacrolimus-induced chronic nephrotoxicity. | 2015 | Nephrology (Carlton) | pmid:26031587 |
Liu Z et al. | Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. | 2015 | Ann. Intern. Med. | pmid:25383558 |
Kaieda S et al. | Successful treatment of macrophage activation syndrome in a patient with dermatomyositis by combination with immunosuppressive therapy and plasmapheresis. | 2015 | Mod Rheumatol | pmid:24252010 |
Kawaoka T et al. | Two patients treated with simeprevir plus pegylated-interferon and ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation: case report. | 2015 | Transplant. Proc. | pmid:25891736 |
Kim YT et al. | Co-treatment effect of pulsed electromagnetic field (PEMF) with human dental pulp stromal cells and FK506 on the regeneration of crush injured rat sciatic nerve. | 2015 | Int. J. Neurosci. | pmid:25271799 |
Ichimaru N et al. | Risk factors and incidence for lipid abnormalities in kidney transplant patients. | 2015 | Transplant. Proc. | pmid:25891708 |
Bruckmueller H et al. | Which Genetic Determinants Should be Considered for Tacrolimus Dose Optimization in Kidney Transplantation? A Combined Analysis of Genes Affecting the CYP3A Locus. | 2015 | Ther Drug Monit | pmid:25271728 |
Lim EJ et al. | Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation. | 2015 | PLoS ONE | pmid:26390404 |
Moscovici BK et al. | Treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop: Prospective double-blind randomized study. | 2015 | Cont Lens Anterior Eye | pmid:25956572 |
Kim D et al. | Hydrogen sulfide and hypoxia-induced changes in TASK (K2P3/9) activity and intracellular Ca(2+) concentration in rat carotid body glomus cells. | 2015 | Respir Physiol Neurobiol | pmid:25956223 |
Soto GAC et al. | Dose increase needed in most cystic fibrosis lung transplantation patients when changing from twice- to once-daily tacrolimus oral administration. | 2015 | Eur. J. Clin. Pharmacol. | pmid:25953736 |
Tabchi S et al. | Successful treatment of Evans syndrome with Tacrolimus. | 2015 | Invest New Drugs | pmid:25209619 |
Papadopoulos-Köhn A et al. | Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant. | 2015 | Transplantation | pmid:25208324 |
Torres-EspÃn A et al. | Immunosuppression of allogenic mesenchymal stem cells transplantation after spinal cord injury improves graft survival and beneficial outcomes. | 2015 | J. Neurotrauma | pmid:25203134 |
Bae JM et al. | Combination therapy with 308-nm excimer laser, topical tacrolimus, and short-term systemic corticosteroids for segmental vitiligo: A retrospective study of 159 patients. | 2015 | J. Am. Acad. Dermatol. | pmid:25956660 |
Rojas L et al. | Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies. | 2015 | Pharmacogenomics J. | pmid:25201288 |
Ennaifer R et al. | Nodular hyperplasia of the gastrointestinal tract after liver transplantation: role of immunosuppressive therapy? A case report. | 2015 | Transplant. Proc. | pmid:25891739 |
Chung YW et al. | Transcriptional activation of nuclear-related factor 2 by FK506 in Jurkat T cells. | 2015 | Transplant. Proc. | pmid:25891728 |
Daunton A et al. | A cutaneous presentation of a common condition. | 2015 | BMJ | pmid:26681202 |
Yang SS et al. | A single center, open-label, randomized pilot study to evaluate the safety and efficacy of tacrolimus modified release, Advagraf, versus tacrolimus twice daily, Prograf, in stable renal recipients (single). | 2015 | Transplant. Proc. | pmid:25891697 |
Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
Malvezzi P and Rostaing L | The safety of calcineurin inhibitors for kidney-transplant patients. | 2015 | Expert Opin Drug Saf | pmid:26329325 |
Hempen CM et al. | Hematocrit-independent recovery of immunosuppressants from DBS using heated flow-through desorption. | 2015 | Bioanalysis | pmid:26327182 |
Manuyakorn W et al. | In vitro cytokine changes after pediatric liver transplantation. | 2015 | Asian Pac. J. Allergy Immunol. | pmid:25840634 |
Pidala J et al. | Prolonged sirolimus administration after allogeneic hematopoietic cell transplantation is associated with decreased risk for moderate-severe chronic graft-versus-host disease. | 2015 | Haematologica | pmid:25840599 |
Tsai MK et al. | B cells and immunoglobulin in ABO-incompatible renal transplant patients receiving rituximab and double filtration plasmapheresis. | 2015 | J. Formos. Med. Assoc. | pmid:25839769 |
Eaton KV et al. | Engineering macrophages to control the inflammatory response and angiogenesis. | 2015 | Exp. Cell Res. | pmid:26610863 |
Rajaganapathy BR et al. | Intravesical Liposomal Tacrolimus Protects against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation. | 2015 | J. Urol. | pmid:25839382 |
Furlan SN et al. | Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention. | 2015 | Sci Transl Med | pmid:26606970 |
Nagashima T and Minota S | Comment on: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. | 2015 | Rheumatology (Oxford) | pmid:25832615 |
Yasuda S et al. | Comment on: The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis: reply. | 2015 | Rheumatology (Oxford) | pmid:25832614 |
Nouchi A et al. | [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. | 2015 | Ann Dermatol Venereol | pmid:25778634 |
Diaz-Siso JR et al. | Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation. | 2015 | Am. J. Transplant. | pmid:25777324 |
Fujibayashi T et al. | Comparison of efficacy and safety of tacrolimus and methotrexate in combination with abatacept in patients with rheumatoid arthritis; a retrospective observational study in the TBC Registry. | 2015 | Mod Rheumatol | pmid:25775147 |
Adotama P et al. | Patient satisfaction with different treatment modalities for vitiligo. | 2015 | J. Am. Acad. Dermatol. | pmid:25773415 |
Lehman N et al. | Left subconjunctival hemorrhage · renal dysfunction · international normalized ratio of 4.5 · Dx? | 2015 | J Fam Pract | pmid:26551480 |
Boloori A et al. | Characterization of Remitting and Relapsing Hyperglycemia in Post-Renal-Transplant Recipients. | 2015 | PLoS ONE | pmid:26551468 |
Lightman S et al. | Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17. | 2015 | Ann. Rheum. Dis. | pmid:25269831 |
Mahajan R et al. | Co-localization of agminated congenital melanocytic nevi with vitiligo vulgaris: an unusual presentation. | 2015 | Int. J. Dermatol. | pmid:25039486 |
Qasim W et al. | Reply to: "To target or not to target viral antigens in HBV related HCC?". | 2015 | J. Hepatol. | pmid:25711420 |
Zitelli K et al. | Eosinophilic folliculitis occurring after stem cell transplant for acute lymphoblastic leukemia: a case report and review. | 2015 | Int. J. Dermatol. | pmid:25039354 |
TruneÄŒka P et al. | Renal Function in De Novo Liver Transplant Recipients Receiving Different Prolonged-Release Tacrolimus Regimens-The DIAMOND Study. | 2015 | Am. J. Transplant. | pmid:25707487 |
Adam R et al. | Improved survival in liver transplant recipients receiving prolonged-release tacrolimus in the European Liver Transplant Registry. | 2015 | Am. J. Transplant. | pmid:25703527 |
Yokoyama Y et al. | Corticosteroid-sparing effect of tacrolimus in the initial treatment of dermatomyositis and polymyositis. | 2015 | Mod Rheumatol | pmid:25775144 |
Asrani SK and O'Leary JG | Can one pill a day keep rejection away? | 2015 | Am. J. Transplant. | pmid:25703394 |
Chen QQ et al. | Kaposi's Varicelliform Eruption During Long-term Treatment of Rosacea with 0.03% Tacrolimus Ointment. | 2015 | Chin. Med. J. | pmid:26481759 |
Kim M et al. | Nail lichen striatus: report of seven cases and review of the literature. | 2015 | Int. J. Dermatol. | pmid:26474189 |
Badri P et al. | Pharmacokinetics and dose recommendations for cyclosporine and tacrolimus when coadministered with ABT-450, ombitasvir, and dasabuvir. | 2015 | Am. J. Transplant. | pmid:25708713 |
Peksa GD et al. | Dosing algorithm for concomitant administration of sirolimus, tacrolimus, and an azole after allogeneic hematopoietic stem cell transplantation. | 2015 | J Oncol Pharm Pract | pmid:24938293 |
Cen J et al. | The new immunosuppressant, isogarcinol, binds directly to its target enzyme calcineurin, unlike cyclosporin A and tacrolimus. | 2015 | Biochimie | pmid:25701551 |
Shengyou Y et al. | Influence of tacrolimus on podocyte injury inducted by angiotensin II. | 2015 | J Renin Angiotensin Aldosterone Syst | pmid:25650384 |
Carenco C et al. | Tacrolimus and the risk of solid cancers after liver transplant: a dose effect relationship. | 2015 | Am. J. Transplant. | pmid:25648361 |
Mizokami D et al. | Tacrolimus prevents laryngotracheal stenosis in an acute-injury rat model. | 2015 | Laryngoscope | pmid:25647147 |
Ferjani H et al. | Tacrolimus and mycophenolate mofetil associations: Induction of oxidative stress or antioxidant effect? | 2015 | Hum Exp Toxicol | pmid:25645822 |
Coelho R et al. | Nodular Regenerative Hyperplasia after Liver Transplantation Complicated with Inferior Vena Cava Stenosis: a Clue for Etiopathogenesis? | 2015 | J Gastrointestin Liver Dis | pmid:26405712 |
Romanowski M et al. | Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26400516 |
RodrÃguez-Perálvarez M et al. | Everolimus is safe within the first month after liver transplantation. | 2015 | Transpl. Immunol. | pmid:26392195 |
Sahin G et al. | Association between endothelial and platelet function markers and adiponectin in renal transplanted recipients on cyclosporine and tacrolimus immunosuppression based therapy. | 2015 | Nephrology (Carlton) | pmid:25650527 |
Sato M et al. | Multifocal Fibrosclerosis with Hypertrophic Pachymeningitis and a Soft Tissue Mass around the Thoracic Vertebral Bodies: A Case Report with Review of the Literature. | 2015 | Intern. Med. | pmid:26328659 |
Niioka T et al. | Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation. | 2015 | Int J Mol Sci | pmid:25594874 |
Chittock J et al. | Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. | 2015 | Acta Derm. Venereol. | pmid:25594610 |
Knops N et al. | The functional implications of common genetic variation in CYP3A5 and ABCB1 in human proximal tubule cells. | 2015 | Mol. Pharm. | pmid:25590378 |
Koch M et al. | De novo mTOR inhibitor-based immunosuppression in ABO-incompatible kidney transplantation. | 2015 | Clin Transplant | pmid:26333844 |
Ge Y et al. | The efficacy of tacrolimus in patients with refractory dermatomyositis/polymyositis: a systematic review. | 2015 | Clin. Rheumatol. | pmid:26328518 |
Velioglu A et al. | Association of BK Virus Titers With Lymphocyte Count in Renal Transplant Patients. | 2015 | Transplant. Proc. | pmid:26093733 |
Demir T et al. | Cancer Screening of Renal Transplant Patients Undergoing Long-Term Immunosuppressive Therapy. | 2015 | Transplant. Proc. | pmid:26093731 |
Shi RZ et al. | Rapid measurement of tacrolimus in whole blood by paper spray-tandem mass spectrometry (PS-MS/MS). | 2015 | Clin. Chim. Acta | pmid:25540885 |
Yang F et al. | A clinicopathological study of renal biopsies from 288 elderly patients: analysis based on 4,185 cases. | 2015 | Int Urol Nephrol | pmid:25539617 |
Webb NJ et al. | Corticosteroid-free Kidney Transplantation Improves Growth: 2-Year Follow-up of the TWIST Randomized Controlled Trial. | 2015 | Transplantation | pmid:25539467 |
Schaap MM et al. | A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens. | 2015 | Arch. Toxicol. | pmid:25270620 |
Coilly A et al. | Once-daily prolonged release tacrolimus in liver transplantation: Experts' literature review and recommendations. | 2015 | Liver Transpl. | pmid:26264233 |
Yoo MC et al. | Steroid-free Liver Transplantation Using Rabbit Antithymocyte Globulin Induction in 500 Consecutive Patients. | 2015 | Transplantation | pmid:25539464 |
Boluda ER | Pediatric small bowel transplantation. | 2015 | Curr Opin Organ Transplant | pmid:26262456 |
Offer K et al. | Efficacy of tacrolimus/mycophenolate mofetil as acute graft-versus-host disease prophylaxis and the impact of subtherapeutic tacrolimus levels in children after matched sibling donor allogeneic hematopoietic cell transplantation. | 2015 | Biol. Blood Marrow Transplant. | pmid:25536217 |
Seeling W et al. | Knowledge-based immunosuppressive therapy for kidney transplant patients--from theoretical model to clinical integration. | 2015 | Stud Health Technol Inform | pmid:26262418 |
Ramachandran R et al. | Role of Tacrolimus only therapy in modified Ponticelli regimen resistant idiopathic membranous glomerulonephritis. | 2015 | Nephrology (Carlton) | pmid:25535867 |
Wardhana EA and Datau | A patient with plaque type morphea mimicking systemic lupus erythematosus. | 2015 | Acta Med Indones | pmid:26260557 |
Kim SH et al. | Conversion of twice-daily to once-daily tacrolimus is safe in stable adult living donor liver transplant recipients. | 2015 | HBPD INT | pmid:26256081 |
Clift DE et al. | Effects of embryonic cyclosporine exposures on brain development and behavior. | 2015 | Behav. Brain Res. | pmid:25591474 |
Li Y et al. | Differential regulation of Tregs and Th17/Th1 cells by a sirolimus-based regimen might be dependent on STAT-signaling in renal transplant recipients. | 2015 | Int. Immunopharmacol. | pmid:26186486 |
Togashi M et al. | Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease. | 2015 | Eur. J. Clin. Pharmacol. | pmid:26184414 |
Shen T et al. | Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation. | 2015 | World J. Gastroenterol. | pmid:26034381 |
Spiekerkoetter E et al. | Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:26177174 |
Inamoto Y et al. | Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia. | 2015 | Biol. Blood Marrow Transplant. | pmid:26033280 |
Mandelbrot DA et al. | Effect of Ramipril on Urinary Protein Excretion in Maintenance Renal Transplant Patients Converted to Sirolimus. | 2015 | Am. J. Transplant. | pmid:26176342 |
Regelmann MO et al. | New-onset diabetes mellitus after pediatric liver transplantation. | 2015 | Pediatr Transplant | pmid:26032592 |
Cilião HL et al. | Cytotoxic and genotoxic effects of high concentrations of the immunosuppressive drugs cyclosporine and tacrolimus in MRC-5 cells. | 2015 | Exp. Toxicol. Pathol. | pmid:25541063 |
Guo CL et al. | Efficacy of Topical Tacrolimus for Erosive Oral Lichen Planus: A Meta-analysis. | 2015 | Chin. Med. Sci. J. | pmid:26960301 |