tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim SK et al. | Inflammatory mimetic microfluidic chip by immobilization of cell adhesion molecules for T cell adhesion. | 2012 | Analyst | pmid:22822477 |
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| Brecht S et al. | FK506 protects against various immune responses and secondary degeneration following cerebral ischemia. | 2009 | Anat Rec (Hoboken) | pmid:19728359 |
| Georgiou GK et al. | Calcineurin inhibitors and male fertility after renal transplantation - a review. | 2016 | Andrologia | pmid:26341518 |
| Lang-Lazdunski L et al. | The effects of FK506 on neurologic and histopathologic outcome after transient spinal cord ischemia induced by aortic cross-clamping in rats. | 2001 | Anesth. Analg. | pmid:11323353 |
| Siniscalchi A et al. | Opioid-induced hyperalgesia and rapid opioid detoxification after tacrolimus administration. | 2008 | Anesth. Analg. | pmid:18227327 |
| Brooksbank RL et al. | Treatment of normal skeletal muscle with FK506 or rapamycin results in halothane-induced muscle contracture. | 1998 | Anesthesiology | pmid:9743407 |
| Chini EN and Walker H | FK506 (tacrolimus) increases halothane-induced Ca2+ release from skeletal muscle sarcoplasmic reticulum. | 2000 | Anesthesiology | pmid:10781282 |
| Brittain DE et al. | Total synthesis of antascomicin B. | 2005 | Angew. Chem. Int. Ed. Engl. | pmid:15806607 |
| Lee KB et al. | Direct monitoring of the inhibition of protein-protein interactions in cells by translocation of PKCδ fusion proteins. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21290501 |
| McKenzie KM et al. | Simultaneous identification of multiple protein targets by using complementary-DNA phage display and a natural-product-mimetic probe. | 2004 | Angew. Chem. Int. Ed. Engl. | pmid:15300693 |
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| Althoff EA and Cornish VW | A bacterial small-molecule three-hybrid system. | 2002 | Angew. Chem. Int. Ed. Engl. | pmid:12203581 |
| Elisaf M and Mikhailidis DP | Statins and renal function. | 2002 Sep-Oct | Angiology | pmid:12365855 |
| Wüthrich B et al. | Atopic eczema: genetics or environment? | 2007 | Ann Agric Environ Med | pmid:18247450 |
| Sahu MK et al. | High blood tacrolimus and hyperkalemia in a heart transplant patient. | Ann Card Anaesth | pmid:28393798 | |
| Philippe F et al. | [Drug eluting stents: from evidence based medicine to clinical practice]. | 2005 | Ann Cardiol Angeiol (Paris) | pmid:16104621 |
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| Busque S et al. | [Hypertrichosis and gingival hypertrophy regression in renal transplants following the substitution of cyclosporin by tacrolimus]. | 1999 | Ann Chir | pmid:10584376 |
| Martin D et al. | [First case in the world of autoreplantation of a limb associated with oral administration of an immunosupressant agent (FK 506-Tacrolimus)]. | 2005 | Ann Chir Plast Esthet | pmid:16087038 |
| Moncourier M et al. | [Granulomatous periocular eruption]. | Ann Dermatol Venereol | pmid:28410769 | |
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| Parodi A et al. | Treatment of rosacea. | 2011 | Ann Dermatol Venereol | pmid:22183101 |
| Schmutz JL et al. | [Pimecrolimus and vaccinations]. | 2007 Jun-Jul | Ann Dermatol Venereol | pmid:17702119 |
| Alquier-Bouffard A et al. | [Chronic actinic dermatitis: treatment with topical tacrolimus (two cases)]. | 2007 Jun-Jul | Ann Dermatol Venereol | pmid:17657183 |
| Schmutz JL | [No increased risk of cancer under pimecrolimus]. | 2016 | Ann Dermatol Venereol | pmid:26708204 |
| Parodi A et al. | [Treatment of rosacea]. | 2011 | Ann Dermatol Venereol | pmid:21907876 |
| Mahé E et al. | [Plane warts in areas of atopic dermatitis treated with tacrolimus ointment]. | 2006 Aug-Sep | Ann Dermatol Venereol | pmid:17053745 |
| Girault PY et al. | [Topical tacrolimus in chronic actinic dermatitis]. | 2008 | Ann Dermatol Venereol | pmid:18929923 |
| Rouxel AM et al. | [Tacrolimus mouthwash as second-line treatment for erosive oral lichen planus]. | 2010 | Ann Dermatol Venereol | pmid:20932447 |
| Schmutz JL et al. | [Contact allergy with tacrolimus then pimecrolimus]. | 2008 | Ann Dermatol Venereol | pmid:18342086 |
| Skowron F et al. | [Important systemic absorption of topical tacrolimus during treatment of severe pemphigus vulgaris]. | 2005 | Ann Dermatol Venereol | pmid:15924053 |
| Martel J et al. | [Subcutaneous mycosis due to Scopulariopsis brevicaulis in an immunocompromised patient]. | 2001 | Ann Dermatol Venereol | pmid:11275588 |
| Nouchi A et al. | [Treatment of angiolymphoid hyperplasia with eosinophilia (ALHE) using topical tacrolimus: Two cases]. | 2015 | Ann Dermatol Venereol | pmid:25778634 |
| Reynaert G et al. | [Streptococcal impetigo at topical tacrolimus application sites in a woman with atopic dermatitis]. | 2007 | Ann Dermatol Venereol | pmid:17389853 |
| Paul C | [Science, marketing and pharmacovigilance: the example of topical calcineurin inhibitors]. | 2007 | Ann Dermatol Venereol | pmid:18033059 |
| Al Gain M et al. | [Sirolimus-induced lymphedema in a kidney-transplant recipient: Partial recovery after changeover to tacrolimus]. | 2015 | Ann Dermatol Venereol | pmid:25683011 |
| Chiheb S et al. | [Behçet's disease]. | 2003 Jun-Jul | Ann Dermatol Venereol | pmid:13679709 |
| Baubion E et al. | [Oral lichen planus and treatment with topical tacrolimus rinse]. | 2009 | Ann Dermatol Venereol | pmid:19328313 |
| Henno A et al. | [Improvement of Netherton syndrome associated erythroderma in two adult sisters through use of topical pimecrolimus]. | 2006 | Ann Dermatol Venereol | pmid:16495860 |
| Michel JL and Gain P | [Topical tacrolimus treatment for ocular cicatricial pemphigoid]. | 2006 | Ann Dermatol Venereol | pmid:16508602 |
| Lacour JP | [Topical tacrolimus in dermatology: what can one expect?]. | 2001 | Ann Dermatol Venereol | pmid:11908129 |
| Macario-Barrel A et al. | [Mouth ulcers in patients receiving tacrolimus]. | 2001 | Ann Dermatol Venereol | pmid:11908135 |
| Firmin D et al. | [Tacrolimus ointment in the treatment of chronic cutaneous graft-versus-host disease]. | 2008 | Ann Dermatol Venereol | pmid:18374862 |
| Ferraro V et al. | [Efficacy of topical tacrolimus in Hailey-Hailey disease]. | 2006 | Ann Dermatol Venereol | pmid:16760841 |
| Fery-Blanco C et al. | [Disseminated molluscum contagiosum during topical treatment of atopic dermatitis with tacrolimus: efficacy of cidofovir]. | 2007 | Ann Dermatol Venereol | pmid:17507844 |
| Lübbe J and Saurat JH | [A monograph on topical tacrolimus (Protopic]. | 2003 | Ann Dermatol Venereol | pmid:12700537 |
| de Prost Y | [The value of topical immunosuppressors in the treatment of atopic dermatitis in children]. | 2005 | Ann Dermatol Venereol | pmid:15984296 |
| Nicolie B | [What is the treatment for atopic dermatitis flares in children?]. | 2005 | Ann Dermatol Venereol | pmid:15984308 |
| de Prost Y | [Can the precautionary principle obstruct therapeutic progress?]. | 2005 Aug-Sep | Ann Dermatol Venereol | pmid:16230911 |