tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Aicher L et al. | Decrease in kidney calbindin-D 28kDa as a possible mechanism mediating cyclosporine A- and FK-506-induced calciuria and tubular mineralization. | 1997 | Biochem. Pharmacol. | pmid:9113092 |
| Ahsan N et al. | Successful reversal of acute vascular rejection in a renal allograft with combined mycophenolate mofetil and tacrolimus as primary immunotherapy. | 1997 | Clin Transplant | pmid:9113443 |
| Mignat C | Clinically significant drug interactions with new immunosuppressive agents. | 1997 | Drug Saf | pmid:9113494 |
| Singh N et al. | Invasive fungal infections in liver transplant recipients receiving tacrolimus as the primary immunosuppressive agent. | 1997 | Clin. Infect. Dis. | pmid:9114144 |
| Eum SY et al. | Inhibition by the immunosuppressive agent FK-506 of antigen-induced airways eosinophilia and bronchial hyperreactivity in mice. | 1997 | Br. J. Pharmacol. | pmid:9117088 |
| Jacobson PA et al. | Stability of tacrolimus in an extemporaneously compounded oral liquid. | 1997 | Am J Health Syst Pharm | pmid:9117806 |
| Wu J et al. | Reversal of multidrug resistance by tacrolimus hydrate. | 1996 | Methods Find Exp Clin Pharmacol | pmid:9121220 |
| Gaber LW et al. | Renal histology with varying FK506 blood levels. | 1997 Feb-Mar | Transplant. Proc. | pmid:9122955 |
| Miller J et al. | FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123008 |
| Jordan ML et al. | Five-year experience with tacrolimus rescue for renal allograft rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123009 |
| Cronin DC et al. | Tacrolimus therapy for refractory renal allograft rejection: experience with steroid withdrawal. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123010 |
| Zhu Y et al. | Prolongation of canine renal allograft survival by combining tacrolimus with antimetabolic agents. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123011 |
| Naraghi RM et al. | Long-term follow-up of tacrolimus rescue therapy for renal allograft rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123013 |
| pmid:9123014 | ||||
| Lyne JC et al. | Cadaveric renal transplantation against a positive historic crossmatch under tacrolimus immunosuppression: long-term follow-up. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123015 |
| Zucker K et al. | Augmentation of mycophenolate mofetil pharmacokinetics in renal transplant patients receiving Prograf and CellCept in combination therapy. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123027 |
| Sellers M et al. | Incidence of late acute rejection and progression to chronic rejection in pediatric liver recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123065 |
| Bonatti H et al. | Liver transplantation for acute liver failure in children under 1 year of age. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123068 |
| Shapiro R | Tacrolimus (FK-506) in kidney transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123077 |
| Cho JH et al. | Chronic rejection in pediatric liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123078 |
| Marino IR et al. | Preoperative assessment of risk in liver transplantation: a multivariate analysis in 2376 cases of the UW era. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123079 |
| Rayes N et al. | Distribution of lymphocyte subtypes in liver transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123103 |
| Platz KP et al. | Impact of immunosuppression and acute rejection on hepatitis B recurrence. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123107 |
| Ko S et al. | Predominant role of local immunosuppressive effect in enhanced efficacy of liposomal FK506 in organ transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123117 |
| Khanna A et al. | Cardiac changes at autopsy in adult liver transplant recipients under tacrolimus. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123118 |
| Busuttil RW and Holt CD | Tacrolimus (FK506) is superior to cyclosporine in liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123119 |
| Gavlik A et al. | Mycophenolate mofetil rescue therapy in liver transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123124 |
| Katoh H et al. | Effectiveness of 15-deoxyspergualin on steroid-resistant acute rejection in living related liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123125 |
| Meiser BM et al. | Tacrolimus (FK506) proves superior to OKT3 for treating episodes of persistent rejection following intrathoracic transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123150 |
| Misao T et al. | Effect of donor splenocyte transfusion with a simultaneous single injection of tacrolimus on lung allografts. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123153 |
| Morozumi K et al. | Electron-microscopic peritubular capillary lesion is a specific and useful diagnostic indicator for chronic rejection of renal allografts showing less specific morphologic lesions in the cyclosporine era. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123167 |
| Zipperle S et al. | Impaired T-cell IL-10 secretion and CD4 helper function in liver transplant patients treated with tacrolimus. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123208 |
| Li W et al. | High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123209 |
| Nakajima H and Oka T | Analysis of biochemical and biological functions of Fas-ligand (FasL) and Fas on activated T cells in allo-immune response. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123217 |
| pmid:9123237 | ||||
| Gassel HJ et al. | Selective immunosuppression induces tolerance after liver transplantation: an immunohistochemical and cytofluorographic analysis of the graft and recipient immune system. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123253 |
| Burke GW et al. | Donor bone marrow infusion in simultaneous pancreas/kidney transplantation with OKT3 induction: evidence for augmentation of chimerism. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123275 |
| Ota H et al. | Intrathymic microchimerism predicts rejection response in allograft recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123279 |
| Tashiro H et al. | Correlation of high-level microchimerism with graft acceptance in rat liver transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123287 |
| Wijnen RM et al. | Thymus atrophy in the nonhuman primate by FK506: an immunohistochemical study. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123292 |
| Kumano K et al. | Role of the transforming growth factor and monocyte chemoattractant protein in FK506-induced nephropathy in the rat. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123293 |
| Grochowicz PM et al. | Synergistic interaction between castanospermine and tacrolimus in a rat heart allograft model. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123296 |
| Guo Z et al. | Leflunomide, a potential immunosuppressant for pancreatic islet transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123314 |
| Walgenbach KJ et al. | Immunocytes of composite tissue allografts express elevated levels of TGF beta mRNA and protein during chronic rejection. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123418 |
| Millis JM et al. | Tacrolimus treatment of steroid-resistant rejection provides economic advantages compared with OKT3 therapy. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123421 |
| Corry RJ et al. | Pancreas transplantation with enteric drainage under tacrolimus induction therapy. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123457 |
| el-Ghoroury M et al. | Efficacy and safety of tacrolimus versus cyclosporine in kidney and pancreas transplant recipients. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123461 |
| Hariharan S et al. | Long-term renal and pancreas function with tacrolimus rescue therapy following kidney/pancreas transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123462 |
| Stratta RJ | Simultaneous use of tacrolimus and mycophenolate mofetil in combined pancreas-kidney transplant recipients: a multi-center report. The FK/MMF Multi-Center Study Group. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123463 |
| Gruessner AC et al. | Solitary pancreas transplants: improving results and factors that influence outcome. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123468 |