tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Basadonna GP et al. | Pancreas after kidney transplantation: HLA mismatch does not preclude success. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123470 |
| Alessiani M et al. | Morphological and functional changes in small-bowel allografts of pigs under combined tacrolimus and mycophenolate mofetil immunosuppression. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123483 |
| Galvao FH et al. | Experimental animal model of graft-versus-host disease (GVHD) after small-bowel transplantation: characteristics of the model and application to developing treatment strategies. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123488 |
| Iacona I et al. | Mycophenolic acid in combination with FK 506: a pharmacokinetic study in piglets after small-bowel transplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123489 |
| Batten P et al. | Effect of cyclosporine A and FK 506 on human T cell responses to xenogeneic and allogeneic endothelium: relative resistance of T cell/porcine endothelial interactions. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123582 |
| Troppmann C et al. | FK 506 versus cyclosporine A for steroid-free synergistic combination therapy with rapamycin in a discordant large animal donor xenoislet transplant model. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123585 |
| Matsumiya G et al. | Serum interleukin-6 level after cardiac xenotransplantation in primates. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123586 |
| Ohdan H et al. | Prolongation of hamster-to-rat liver xenograft survival by donor bone marrow augmentation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123589 |
| Yamagami S et al. | Rejection mechanism and immunosuppression by FK 506 and anti-leukocyte function associated antigen-1 antibody in concordant corneal xenotransplantation. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123598 |
| Mondragon A et al. | Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. | 1997 | Biochemistry | pmid:9125515 |
| Murthy JN et al. | Identification of a 37 kDa tacrolimus, sirolimus and cyclosporine binding immunophilin possessing glyceraldehyde 3-phosphate dehydrogenase activity isolated from the Jurkat T cell line. | 1997 | Clin. Biochem. | pmid:9127694 |
| Schreiber SL and Crabtree GR | Immunophilins, ligands, and the control of signal transduction. | 1995-1996 | Harvey Lect. | pmid:9127988 |
| Ferron GM et al. | Population pharmacokinetics of sirolimus in kidney transplant patients. | 1997 | Clin. Pharmacol. Ther. | pmid:9129559 |
| Weil SJ et al. | Chemotaxis of macrophages by a peritoneal fluid protein in women with endometriosis. | 1997 | Fertil. Steril. | pmid:9130891 |
| Karlsson H et al. | Energy levels in resting and mitogen-stimulated human lymphocytes during treatment with FK506 or cyclosporin A in vitro. | 1997 | Biochim. Biophys. Acta | pmid:9131051 |
| Pratt WB | The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase. | 1997 | Annu. Rev. Pharmacol. Toxicol. | pmid:9131255 |
| Filler G et al. | Transient diabetes mellitus and peripheral insulin resistance following Tacrolimus intoxication in a child after renal transplantation. | 1997 | Nephrol. Dial. Transplant. | pmid:9132657 |
| Yap AS et al. | Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function. | 1997 | Curr. Biol. | pmid:9133345 |
| Chudek J et al. | [The role of endothelin in the physiology and pathophysiology of the circulatory system and kidneys]. | 1996 | Pol. Arch. Med. Wewn. | pmid:9139279 |
| Landström M and Funa K | Apoptosis in rat prostatic adenocarcinoma is associated with rapid infiltration of cytotoxic T-cells and activated macrophages. | 1997 | Int. J. Cancer | pmid:9139883 |
| Azuma H et al. | Atypical Epstein-Barr virus infection during and after intermittent FK506 therapy. | 1997 | Acta Paediatr Jpn | pmid:9141259 |
| Tsuchida Y et al. | Vascularized bone marrow allotransplantation in rats prolongs a simultaneous skin allograft. | 1997 | Transplant. Proc. | pmid:9142252 |
| Costa A et al. | Small bowel myoelectrical activity after transplantation in pigs: motility versus ACR score. | 1997 | Transplant. Proc. | pmid:9142281 |
| Soin AS et al. | Complement activation during rejection in experimental intestinal transplantation. | 1997 | Transplant. Proc. | pmid:9142282 |
| Rossi G et al. | Small bowel transplantation under oral immunosuppression: experimental study in the pig. | 1997 | Transplant. Proc. | pmid:9142285 |
| Spada M et al. | Tacrolimus and mycophenolate mofetil in pig small bowel transplantation: different protocols and their outcome. | 1997 | Transplant. Proc. | pmid:9142286 |
| Ronchetti F et al. | Intestinal damage evaluation in swine allograft small bowel through hyaluronic acid quantification. | 1997 | Transplant. Proc. | pmid:9142293 |
| Velio P et al. | Combined orthotopic liver-small bowel transplantation or small bowel transplantation in pigs: relations between survival, rejection, and mucosal morphometry. | 1997 | Transplant. Proc. | pmid:9142295 |
| Regazzi MB et al. | Pharmacokinetics of FK506 and mycophenolic acid in experimental and clinical intestinal transplantation. | 1997 | Transplant. Proc. | pmid:9142302 |
| Hansen LJ et al. | Early pharmacokinetic profiles of enteral tacrolimus after multivisceral transplantation. | 1997 | Transplant. Proc. | pmid:9142303 |
| Guérette B et al. | Control of inflammatory damage by anti-LFA-1: increase success of myoblast transplantation. | 1997 Mar-Apr | Cell Transplant | pmid:9142441 |
| Tanaka K et al. | Calcineurin inhibitor, FK506, prevents reduction in the binding capacity of cyclic AMP-dependent protein kinase in ischemic gerbil brain. | 1997 | J. Cereb. Blood Flow Metab. | pmid:9143223 |
| Galley Y et al. | Jun NH2-terminal kinase is constitutively activated in T cells transformed by the intracellular parasite Theileria parva. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9144200 |
| Soman KV et al. | Template-based docking of a prolactin receptor proline-rich motif octapeptide to FKBP12: implications for cytokine receptor signaling. | 1997 | Protein Sci. | pmid:9144770 |
| Wong PW and Pessah IN | Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12-dependent mechanism. | 1997 | Mol. Pharmacol. | pmid:9145907 |
| Sandborn WJ | Preliminary report on the use of oral tacrolimus (FK506) in the treatment of complicated proximal small bowel and fistulizing Crohn's disease. | 1997 | Am. J. Gastroenterol. | pmid:9149205 |
| Katoh H et al. | Living related partial liver transplantation in biliary atresia: 11 cases of experience. | 1997 | Tohoku J. Exp. Med. | pmid:9149348 |
| Steffen R et al. | Autoimmune enteropathy in a pediatric patient: partial response to tacrolimus therapy. | 1997 | Clin Pediatr (Phila) | pmid:9152557 |
| Chow FS et al. | Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion. | 1997 | Drug Metab. Dispos. | pmid:9152601 |
| Araki T et al. | Effects of vinconate on age-related alterations in [3H]MK-801, [3H]glycine, sodium-dependent D-[3H]aspartate, [3H]FK-506 and [3H]PN200-110 binding in rats. | 1997 | Mech. Ageing Dev. | pmid:9152958 |
| Banholzer R et al. | Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3' untranslated region. | 1997 | Mol. Cell. Biol. | pmid:9154824 |
| Delehanty LL et al. | Apoptosis in a Fas-resistant, T-cell receptor-sensitive human leukaemic T-cell clone. | 1997 | Immunology | pmid:9155645 |
| Iyengar AR et al. | Striking augmentation of hematopoietic cell chimerism in noncytoablated allogeneic bone marrow recipients by FLT3 ligand and tacrolimus. | 1997 | Transplantation | pmid:9158008 |
| van Hooff JP | Pneumocystis carinii pneumonia after renal transplantation. | 1997 | Transplantation | pmid:9158038 |
| Siddiqui MA et al. | Lymphomatoid papulosis and FK 506. | 1997 | Int. J. Dermatol. | pmid:9159004 |
| Seifeldin RA et al. | Nifedipine interaction with tacrolimus in liver transplant recipients. | 1997 | Ann Pharmacother | pmid:9161650 |
| Homey B et al. | A local lymph node assay to analyse immunosuppressive effects of topically applied drugs. | 1997 | Eur. J. Pharmacol. | pmid:9163567 |
| Klupp J et al. | Mycophenolate mofetil added to immunosuppression after liver transplantation--first results. | 1997 | Transpl. Int. | pmid:9163864 |
| McKee M et al. | Initial experience with FK506 (tacrolimus) in pediatric renal transplant recipients. | 1997 | J. Pediatr. Surg. | pmid:9165452 |
| Min DI et al. | Time-dependent disposition of tacrolimus and its effect on endothelin-1 in liver allograft recipients. | 1997 May-Jun | Pharmacotherapy | pmid:9165550 |