tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Penson MG et al. Tacrolimus-based triple-drug immunosuppression minimizes serum lipid elevations in pediatric cardiac transplant recipients. 1999 J. Heart Lung Transplant. pmid:10452348
Jones JW et al. Long-term survival of an extremity composite tissue allograft with FK506-mycophenolate mofetil therapy. 1999 Surgery pmid:10455910
Miura S et al. The beneficial effects of FK 506 on living-related renal transplantation in presensitized recipients. 1999 Transplant. Proc. pmid:10455940
Jiang H and Kobayashi M Differences between cyclosporin A and tacrolimus in organ transplantation. 1999 Transplant. Proc. pmid:10455942
Kobashigawa JA Postoperative management following heart transplantation. 1999 Transplant. Proc. pmid:10455966
Hachida M et al. Combined use of deoxyspergualin and FK 506 for temporary circulatory assist. 1999 Transplant. Proc. pmid:10455968
Van Gelder RN and Kaplan HJ Immunosuppression in uveitis therapy. 1999 Springer Semin. Immunopathol. pmid:10457590
Drachenberg CB et al. Islet cell damage associated with tacrolimus and cyclosporine: morphological features in pancreas allograft biopsies and clinical correlation. 1999 Transplantation pmid:10459544
Burke GA et al. The role of early renal biopsy in cyclosporin induced thrombotic microangiopathy. 1999 Pediatr. Nephrol. pmid:10460501
Morris-Stiff GJ et al. Conversion from cyclosporin (Neoral) to tacrolimus (Prograf) in renal allograft recipients with chronic graft nephropathy: results of an observational study. 1999 Transpl. Int. pmid:10460877
Gold BG FK506 and the role of the immunophilin FKBP-52 in nerve regeneration. 1999 Drug Metab. Rev. pmid:10461545
Arndt C et al. Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. 1999 Microbiology (Reading, Engl.) pmid:10463165
Wandel C et al. P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies. 1999 Cancer Res. pmid:10463589
Alexanian AR and Bamburg JR Neuronal survival activity of s100betabeta is enhanced by calcineurin inhibitors and requires activation of NF-kappaB. 1999 FASEB J. pmid:10463953
Shuto H et al. Inhibition of GABA system involved in cyclosporine-induced convulsions. 1999 Life Sci. pmid:10465348
Ivery MT A proposed molecular model for the interaction of calcineurin with the cyclosporin A-cyclophilin A complex. 1999 Bioorg. Med. Chem. pmid:10465413
Johnson CE and Truong NM Stability and compatibility of tacrolimus and fluconazole in 0.9% sodium chloride. 1999 Jul-Aug J Am Pharm Assoc (Wash) pmid:10467814
Ogino Y et al. Comparison of cyclosporin A and tacrolimus concentrations in whole blood between jejunal and ileal transplanted rats. 1999 J. Pharm. Pharmacol. pmid:10467956
Yokogawa K et al. P-glycoprotein-dependent disposition kinetics of tacrolimus: studies in mdr1a knockout mice. 1999 Pharm. Res. pmid:10468022
Grassberger M et al. A novel anti-inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: in vitro pharmacology. 1999 Br. J. Dermatol. pmid:10468798