tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Caraveo G et al. FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229832
Varshosaz J et al. Physicochemical, Pharmacodynamic and Pharmacokinetic Characterization of Soluplus Stabilized Nanosuspension of Tacrolimus. 2017 Curr Drug Deliv pmid:27697037
Liu C et al. Tacrolimus Improves Symptoms of Children With Myasthenia Gravis Refractory to Prednisone. 2017 Pediatr. Neurol. pmid:29074055
Cheung AY et al. Probable Donor-Derived Cytomegalovirus Disease After Keratolimbal Allograft Transplantation. 2017 Cornea pmid:28614157
Weir MR et al. Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial. 2017 Transplantation pmid:26950714
Koo K et al. Beyond monotherapy: a systematic review on creative strategies in topical therapy of psoriasis. 2017 J Dermatolog Treat pmid:28481664
Wolfshohl JA et al. Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment. 2017 Lasers Surg Med pmid:27552666
Gardenier JC et al. Topical tacrolimus for the treatment of secondary lymphedema. 2017 Nat Commun pmid:28186091
Kizilbash SJ et al. Infection rates in tacrolimus versus cyclosporine-treated pediatric kidney transplant recipients on a rapid discontinuation of prednisone protocol: 1-year analysis. 2017 Pediatr Transplant pmid:28371243
Wang J et al. Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil. 2017 Appl. Microbiol. Biotechnol. pmid:28175948
Ikeda K et al. Intestinal perforation due to hemorrhagic Cytomegalovirus enteritis in a patient with severe uncontrolled lupus nephritis: a case and review of the literature. 2017 Rheumatol. Int. pmid:28283734
Ribero S and Borradori L Re: risk of malignancy and systemic absorption after application of topical tacrolimus in oral lichen planus. 2017 J Eur Acad Dermatol Venereol pmid:27291784
Piotti G et al. Once-daily prolonged-release tacrolimus formulations for kidney transplantation: what the nephrologist needs to know. 2017 J. Nephrol. pmid:27206763
Ma TK et al. Therapeutic drug monitoring of once-daily tacrolimus (Advagraf) in a gastrectomized kidney transplant recipient. 2017 Nephrology (Carlton) pmid:28064453
Percy C et al. Impact of Acute Infection Requiring Hospitalization on Tacrolimus Blood Levels in Kidney Transplant Recipients. 2017 Transplant. Proc. pmid:29149962
de Menezes AF et al. Pharmacologic Treatment of Vitiligo in Children and Adolescents: A Systematic Review. 2017 Pediatr Dermatol pmid:27878842
Taber DJ et al. A Comparative Effectiveness Analysis of Early Steroid Withdrawal in Black Kidney Transplant Recipients. 2017 Clin J Am Soc Nephrol pmid:27979979
Flahault A et al. Clinical impact of the CYP3A5 6986A>G allelic variant on kidney transplantation outcomes. 2017 Pharmacogenomics pmid:27977332
Ganschow R et al. Everolimus and reduced calcineurin inhibitor therapy in pediatric liver transplant recipients: Results from a multicenter, prospective study. 2017 Pediatr Transplant pmid:28714558
Tsunashima D et al. Development of extended-release solid dispersion granules of tacrolimus: evaluation of release mechanism and human oral bioavailability. 2017 J. Pharm. Pharmacol. pmid:28872687