| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| St A Nunes FA and Lucey MR | Searching for a balance when applying immunosuppression after liver transplantation. | 2001 | Transplantation | pmid:11258425 |
| Ringe B et al. | A novel management strategy of steroid-free immunosuppression after liver transplantation: efficacy and safety of tacrolimus and mycophenolate mofetil. | 2001 | Transplantation | pmid:11258429 |
| Matsuda S et al. | Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation. | 2000 | EMBO Rep. | pmid:11258483 |
| Queille-Roussel C et al. | The new topical ascomycin derivative SDZ ASM 981 does not induce skin atrophy when applied to normal skin for 4 weeks: a randomized, double-blind controlled study. | 2001 | Br. J. Dermatol. | pmid:11260007 |
| Weir MR et al. | Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy. | 2001 | Kidney Int. | pmid:11260422 |
| Chand DH et al. | Tacrolimus: the good, the bad, and the ugly. | 2001 | Pediatr Transplant | pmid:11260486 |
| Grotz WH et al. | Calcineurin-inhibitor induced pain syndrome (CIPS): a severe disabling complication after organ transplantation. | 2001 | Transpl. Int. | pmid:11263551 |
| Nikiforow S et al. | CD4+ T-cell effectors inhibit Epstein-Barr virus-induced B-cell proliferation. | 2001 | J. Virol. | pmid:11264363 |
| Vasquez E et al. | Clotrimazole increases tacrolimus blood levels: a drug interaction in kidney transplant patients. | 2001 | Clin Transplant | pmid:11264634 |
| Nagashima N et al. | Decreased effect of immunosuppression on immunocompetence in African--Americans after kidney and liver transplantation. | 2001 | Clin Transplant | pmid:11264637 |
| Ciancio G et al. | The use of intravenous tacrolimus and mycophenolate mofetil as induction and maintenance immunosuppression in simultaneous pancreas--kidney recipients with previous transplants. | 2001 | Clin Transplant | pmid:11264642 |
| Utsugi R et al. | Tolerance across a two-haplotype, fully MHC-mismatched barrier induced in miniature swine renal allografts treated with a 12-day course of tacrolimus. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266727 |
| Gasser M et al. | Putative regulatory function of alloreactive Th2 cells in tolerant recipients after small bowel transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266759 |
| Nakao A et al. | Changes of allo-intestinal graft survival and intragraft cytokine expression by bone marrow augmentation with tacrolimus treatment in rats. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266851 |
| Janezic AL et al. | Alternatively spliced variants of IL-2 mRNA in sequential transplant kidney core needle biopsies. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266873 |
| Opelz G | New immunosuppressants and HLA matching. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266911 |
| Jiang H et al. | IL-10: a tacrolimus-specific cytotoxic mediator in ongoing allograft rejection. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266931 |
| Orsenigo R et al. | FK506 and SMS 201-995: effect on heterotopic heart transplantation in rats. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266956 |
| Ishibashi M et al. | Experimental study of tacrolimus immunosuppression on the mode of administration: efficacy of constant intravenous infusion avoiding C(max). | 2001 Feb-Mar | Transplant. Proc. | pmid:11266958 |
| Erickson LM et al. | Gene expression profiles of rat heart allografts with immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11266960 |
| Reutzel-Selke A et al. | Donor pretreatment of grafts from marginal donors improves long-term graft outcome. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267150 |
| Ettenger R | The practical problems of prednisone in pediatric renal transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267159 |
| Berloco P et al. | Tacrolimus as cornerstone immunosuppressant in kidney transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267161 |
| Ciancio G et al. | Daclizumab induction for primary kidney transplant recipients using tacrolimus, mycophenolate mofetil, and steroids as maintenance immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267169 |
| Vincenti F | Tacrolimus (FK 506) in kidney transplantation: five-year survival results of the U.S. multicenter, randomized, comparative trial. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267172 |
| Calconi G and Vianello A | One-year follow-up of a large European trial comparing dual versus triple tacrolimus-based immunosuppressive regimens following renal transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267173 |
| Pretagostini R et al. | Conversion from cyclosporin to tacrolimus in chronic allograft nephropathy. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267174 |
| Abouljoud M et al. | Conversion to neoral provides effective rescue therapy for liver and kidney transplant patients intolerant of Prograf. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267175 |
| Kauffman HM et al. | Drug regimens affect cadaveric kidney graft survival. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267176 |
| Dudley CR | Conversion at first rejection: a prospective trial comparing cyclosporine microemulsion with tacrolimus in renal transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267179 |
| Wang W et al. | Effect of rapamycin and FK506 on mesangial cell proliferation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267180 |
| Salazar A et al. | Sirolimus-tacrolimus combination for combined kidney-pancreas transplantation: effect on renal function. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267181 |
| Zaltzman J et al. | Tacrolimus, MMF, steroid, and ALG immunotherapy for high immunological risk renal transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267183 |
| Zamauskaite A et al. | FK506 and CsA differ in their effect on intracellular cytokine expression following kidney transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267184 |
| Aguirrezabalaga J et al. | Lipid profiles in liver transplantation in patients receiving tacrolimus or cyclosporin. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267192 |
| Shishido S et al. | Pharmacokinetics of tacrolimus in pediatric renal transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267193 |
| Glanemann M et al. | Mycophenolate mofetil is superior in combination with tacrolimus compared to cyclosporine for immunosuppressive therapy after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267194 |
| van den Berg AP et al. | Prediction of the inhibition of IL-2 production by calcineurin inhibitors. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267197 |
| Wu M et al. | Cyclosporine and tacrolimus alter renin-angiotesin system in mouse medullary-thick ascending limb cultured cells. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267198 |
| Luke PP et al. | IVIG rescue therapy in renal transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267206 |
| Felipe CR et al. | Choosing the right dose of new immunossuppressive drugs for new populations: importance of pharmacokinetic studies. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267207 |
| Evans NJ et al. | The expression of endothelin and inducible nitric oxide synthase in human renal allografts and their role in chronic renal allograft nephropathy. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267247 |
| Cailhier JF et al. | CMV in kidney transplants in the tacrolimus-mycophenolate era. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267255 |
| Quiroga I et al. | Differential homocysteine levels in renal transplant patients receiving neoral versus tacrolimus. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267261 |
| Chakrabarti P et al. | Outcome after steroid withdrawal in adult renal transplant patients receiving tacrolimus-based immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267274 |
| Del Castillo D | Analysis of primary and recurrent rejection following renal transplantation in a large, comparative, multicentre trial. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267283 |
| Busque S et al. | Canadian multicentre trial of tacrolimus/azathioprine/steroids versus tacrolimus/mycophenolate mofetil/steroids versus neoral/mycophenolate mofetil/steroids in renal transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267285 |
| Sperschneider H | A large, multicentre trial to compare the efficacy and safety of tacrolimus with cyclosporine microemulsion following renal transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267291 |
| Mühlbacher F | Tacrolimus versus cyclosporin microemulsion in liver transplantation: results of a 3-month study. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267317 |
| Peltekian K et al. | De novo use of low-dose tacrolimus and sirolimus in liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267318 |
| Jain A et al. | Prospective randomized trial of tacrolimus and prednisone versus tacrolimus, prednisone, and mycophenolate mofetil: complete report on 350 primary adult liver transplantations. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267319 |
| Mueller AR et al. | Influence of immunosuppression on patient survival after liver transplantation for hepatitis C. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267321 |
| Mohamed MA et al. | TGF-beta expression in protocol transplant liver biopsies: a comparative study between cyclosporine-A (CyA) and tacrolimus (FK 506) immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267336 |
| Shokouh-Amiri MH et al. | The importance of early prevention of renal dysfunction in liver transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267345 |
| Markus BH et al. | Daclizumab induction therapy in combination with tacrolimus. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267354 |
| Langrehr JM et al. | IL-2 receptor antibody induction increases the risk for chronic rejection after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267360 |
| Heffron TG et al. | Single-dose induction with daclizumab immediately after liver transplantation in pediatric patients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267368 |
| Groetzner J et al. | Tacrolimus or cyclosporine for immunosuppression after cardiac transplantation: which treatment reveals more side effects during long-term follow-up? | 2001 Feb-Mar | Transplant. Proc. | pmid:11267373 |
| van den Berg AP et al. | Recurrent HCV infection reduces the requirement for tacrolimus after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267375 |
| Pirenne J et al. | Standard cyclosporine A-based versus completely steroid-free FK506-based immunosuppression after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267396 |
| Langrehr JM et al. | A prospective, randomized trial with quadruple versus dual tacrolimus-based induction after liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267404 |
| Heffron TG et al. | Daclizumab induction in liver transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267408 |
| Rabkin JM et al. | Pharmacoeconomic study of tacrolimus-based versus cyclosporine-based immunosuppressive therapy following liver transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267411 |
| Uber PA et al. | Ethnic disparities in the pharmacologic characteristics of tacrolimus in heart transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267428 |
| Banerjee R et al. | Coadministration of itraconazole and tacrolimus after thoracic organ transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267435 |
| Mehra MR et al. | A randomized comparison of an immunosuppressive strategy using tacrolimus and cyclosporine in black heart transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267438 |
| Mehra MR et al. | Racial differences in clinical outcome using tacrolimus and mycophenolate mofetil immunosuppression in heart transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267442 |
| Treede H et al. | Incidence and spectrum of infections in lung transplanted patients: comparison of four different immunosuppressive protocols. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267444 |
| Jordan ML et al. | Steroid withdrawal for pancreas transplants under tacrolimus immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267456 |
| Lo A et al. | Outcome of simultaneous kidney-pancreas transplantation in African-American recipients: a case control study. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267465 |
| Burke GW et al. | Ten-year survival after simultaneous pancreas/kidney transplantation with bladder drainage and tacrolimus-based immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267467 |
| Kahl A et al. | Long-term prednisolone withdrawal after pancreas and kidney transplantation in patients treated with ATG, tacrolimus, and mycophenolate mofetil. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267473 |
| McCauley J et al. | Long-term lipid metabolism in combined kidney-pancreas transplant recipients under tacrolimus immunosuppression. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267475 |
| Lo A et al. | Limited benefits of induction with monoclonal antibody to interleukin-2 receptor in combination with tacrolimus, mycophenolate mofetil, and steroids in simultaneous kidney-pancreas transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267477 |
| Owen ER et al. | Peripheral nerve regeneration in human hand transplantation. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267484 |
| Molmenti EP et al. | Incidence, management, and outcome of posttransplant lymphoproliferative disease in pediatric liver transplant recipients. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267487 |
| Spada M et al. | A cause of late graft dysfunction after liver transplantation in children: de-novo autoimmune hepatitis. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267495 |
| Lo A et al. | Ganciclovir prophylaxis for cytomegalovirus infection in simultaneous kidney-pancreas transplant recipients receiving tacrolimus, mycophenolate mofetil, and prednisone. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267516 |
| Reimer J et al. | Quality of life after kidney transplantation--the impact of tacrolimus. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267573 |
| Jain A et al. | Pharmacokinetics of mycophenolic acid after mycophenolate mofetil administration in liver transplant patients treated with tacrolimus. | 2001 | J Clin Pharmacol | pmid:11269567 |
| Bekersky I et al. | Effect of time of meal consumption on bioavailability of a single oral 5 mg tacrolimus dose. | 2001 | J Clin Pharmacol | pmid:11269569 |
| Ericzon B et al. | Glucose metabolism in liver transplant recipients treated with FK 506 or cyclosporin in the European multicentre study. | 1994 | Transpl. Int. | pmid:11271178 |
| Undre N and Möller A | Pharmacokinetic interpretation of FK 506 levels in blood and in plasma during a European randomised study in primary liver transplant patients. The FK 506 European Study Group. | 1994 | Transpl. Int. | pmid:11271189 |
| Yano K et al. | Effects of intrahepatic arterial and intraportal administration of FK 506 on liver allograft survival in rats. | 1994 | Transpl. Int. | pmid:11271200 |
| Devlin J et al. | Renal complications and development of hypertension in the European study of FK 506 and cyclosporin in primary liver transplant recipients. | 1994 | Transpl. Int. | pmid:11271207 |
| Two-year follow-up study of the efficacy and safety of FK 506 in kidney transplant patients. Japanese FK 506 Study Group. | 1994 | Transpl. Int. | pmid:11271216 | |
| Neuhaus P et al. | Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation. | 1994 | Transpl. Int. | pmid:11271222 |
| Bismuth H et al. | Focus on intractable rejection: 6-month results of the European multicentre liver study of FK 506 and cyclosporin A. | 1994 | Transpl. Int. | pmid:11271231 |
| McMaster P | Patient and graft survival in the European Multicentre Liver Study--FK 506 vs cyclosporin A. | 1994 | Transpl. Int. | pmid:11271239 |
| Mueller AR et al. | Neurotoxicity after orthotopic liver transplantation in cyclosporin A- and FK 506-treated patients. | 1994 | Transpl. Int. | pmid:11271254 |
| D'Silva M et al. | The immunomodulatory effects of a novel agent, leflunomide, in rat cardiac allotransplantation. | 1994 | Transpl. Int. | pmid:11271257 |
| Trocha K et al. | Neurological examinations after liver transplantation concerning patients under corticosteroid immunosuppression and either FK 506 or cyclosporin. | 1994 | Transpl. Int. | pmid:11271273 |
| Ishii T et al. | Immunodepressants ameliorate normothermic ischemia injury to the rat liver by down-regulating tumor necrosis factor, not by alleviation of lipid peroxidative injury. | 1994 | Transpl. Int. | pmid:11271294 |
| Platz KP et al. | Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients. | 1994 | Transpl. Int. | pmid:11271297 |
| Metcalfe S et al. | FK 506 and cyclosporin each block antigen-induced T cell receptor signalling that is dependent on CD4 co-receptor and operates in the absence of detectable cytoplasmic calcium fluxes. | 1994 | Transpl. Int. | pmid:11271304 |
| Moutabarrik A et al. | Effect of immunosuppressive agents FK 506 and cyclosporin and steroids on the expression of IL-6 and its receptor by stimulated lymphocytes and monocytes. | 1994 | Transpl. Int. | pmid:11271305 |
| Winkler M et al. | Optimal FK 506 dosage in patients under primary immunosuppression following liver transplantation. | 1994 | Transpl. Int. | pmid:11271312 |
| Devlin J et al. | FK 506 primary immunosuppression following emergency liver transplantation for fulminant hepatic failure. European FK 506 Study Liver Group. | 1994 | Transpl. Int. | pmid:11271328 |
| Otto G et al. | Corticosteroids and concomitant medication in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation. | 1994 | Transpl. Int. | pmid:11271338 |
| Wong P et al. | FK 506 rescue therapy for intractable liver allograft rejection. | 1994 | Transpl. Int. | pmid:11271339 |