| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Choudhry S et al. | Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. | 2009 | Am. J. Kidney Dis. | pmid:19268410 |
| Haas M et al. | Smooth muscle-specific actin levels in the urine of renal transplant recipients: correlation with cyclosporine or tacrolimus nephrotoxicity. | 1999 | Am. J. Kidney Dis. | pmid:10401019 |
| Wong TY et al. | Parvovirus B19 infection causing red cell aplasia in renal transplantation on tacrolimus. | 1999 | Am. J. Kidney Dis. | pmid:10585325 |
| Hricik DE | Safety and efficacy of TOR inhibitors and other immunosuppressive regimens in African-American renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11583939 |
| Pescovitz MD and Govani M | Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11583940 |
| Tang S et al. | Use of tacrolimus in steroid- and cyclophosphamide-resistant minimal change nephrotic syndrome. | 2003 | Am. J. Kidney Dis. | pmid:14582073 |
| Pham PT et al. | Cyclosporine and tacrolimus-associated thrombotic microangiopathy. | 2000 | Am. J. Kidney Dis. | pmid:11007689 |
| Revelo MP et al. | A 14-year-old boy with kidney allograft failure in the first month after transplantation. | 2000 | Am. J. Kidney Dis. | pmid:11007695 |
| Lien YH and Bracamonte ER | Quiz page February 2011: acute kidney injury, graft pain, and subtherapeutic levels of tacrolimus. | 2011 | Am. J. Kidney Dis. | pmid:21251536 |
| Pavan M et al. | Altered bioavailability of tacrolimus following intravenous administration of tigecycline. | 2011 | Am. J. Kidney Dis. | pmid:21251548 |
| Vischini G et al. | Increased plasma levels of tacrolimus after ingestion of green tea. | 2011 | Am. J. Kidney Dis. | pmid:21787983 |
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| Al-Awwa IA et al. | Importance of allograft biopsy in renal transplant recipients: correlation between clinical and histological diagnosis. | 1998 | Am. J. Kidney Dis. | pmid:9631859 |
| Lum EL et al. | Acute Kidney Allograft Rejection Precipitated by Lenalidomide Treatment for Multiple Myeloma. | 2017 | Am. J. Kidney Dis. | pmid:28189378 |
| Neylan JF et al. | Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. | 1998 | Am. J. Kidney Dis. | pmid:9820446 |
| Chen W et al. | Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: A multicenter randomized clinical trial. | 2011 | Am. J. Kidney Dis. | pmid:21177013 |
| Mertz D et al. | Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus. | 2009 | Am. J. Kidney Dis. | pmid:19346040 |
| Israni A et al. | Conversion to tacrolimus for the treatment of cyclosporine-associated nephrotoxicity in heart transplant recipients. | 2002 | Am. J. Kidney Dis. | pmid:11877596 |
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| Reese PP et al. | Automated Reminders and Physician Notification to Promote Immunosuppression Adherence Among Kidney Transplant Recipients: A Randomized Trial. | 2017 | Am. J. Kidney Dis. | pmid:27940063 |
| Mathis AS and Friedman GS | Coadministration of digoxin with itraconazole in renal transplant recipients. | 2001 | Am. J. Kidney Dis. | pmid:11157404 |
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| Hsu MS et al. | Clinical features and outcome of tuberculosis in solid organ transplant recipients. | 2007 | Am. J. Med. Sci. | pmid:17700199 |
| Ocampo-Garza J et al. | Acquired Hyperpigmentation and Cicatricial Alopecia. | 2016 | Am. J. Med. Sci. | pmid:27524226 |
| Chen M et al. | Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trial. | 2010 | Am. J. Med. Sci. | pmid:20220333 |
| Esposito C et al. | Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats. | 2011 | Am. J. Nephrol. | pmid:21358177 |
| Ren H et al. | Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trial. | 2013 | Am. J. Nephrol. | pmid:23343906 |
| Araujo LP et al. | Interaction of the anti-inflammatory annexin A1 protein and tacrolimus immunosuppressant in the renal function of rats. | 2010 | Am. J. Nephrol. | pmid:20484890 |
| Fourtounas C et al. | Different immunosuppressive combinations on T-cell regulation in renal transplant recipients. | 2010 | Am. J. Nephrol. | pmid:20484893 |
| Bhimma R et al. | Management of steroid-resistant focal segmental glomerulosclerosis in children using tacrolimus. | 2006 | Am. J. Nephrol. | pmid:17159342 |
| Ferreira A et al. | Donor-Specific Anti-Human Leukocyte Antigens Antibodies, Acute Rejection, Renal Function, and Histology in Kidney Transplant Recipients Receiving Tacrolimus and Everolimus. | 2017 | Am. J. Nephrol. | pmid:28511172 |
| Tsipotis E et al. | Bioavailability, Efficacy and Safety of Generic Immunosuppressive Drugs for Kidney Transplantation: A Systematic Review and Meta-Analysis. | 2016 | Am. J. Nephrol. | pmid:27576318 |
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| Zhang Q et al. | Tacrolimus improves the proteinuria remission in patients with refractory IgA nephropathy. | 2012 | Am. J. Nephrol. | pmid:22456060 |
| Li J et al. | Evaluation of mycophenolic acid exposure using a limited sampling strategy in renal transplant recipients. | 2013 | Am. J. Nephrol. | pmid:23689735 |
| Lee CT et al. | Effects of cyclosporine, tacrolimus and rapamycin on renal calcium transport and vitamin D metabolism. | 2011 | Am. J. Nephrol. | pmid:21691056 |
| Soubhia RM et al. | Tacrolimus and nonsteroidal anti-inflammatory drugs: an association to be avoided. | 2005 Jul-Aug | Am. J. Nephrol. | pmid:15976495 |
| Dai DS et al. | Protective Effect of Salvia Przewalskii Extract on Puromycin-Induced Podocyte Injury. | 2015 | Am. J. Nephrol. | pmid:26439819 |
| El-Dahshan KF et al. | Ketoconazole-tacrolimus coadministration in kidney transplant recipients: two-year results of a prospective randomized study. | 2006 | Am. J. Nephrol. | pmid:16804292 |
| Jin J et al. | Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway. | 2016 | Am. J. Nephrol. | pmid:27174564 |
| Weir MR et al. | Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. | 2004 Jul-Aug | Am. J. Nephrol. | pmid:15237243 |
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| von Felbert V et al. | Squamous cell carcinoma arising from a localized vulval lesion of Hailey-Hailey disease after tacrolimus therapy. | 2010 | Am. J. Obstet. Gynecol. | pmid:20816142 |
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