Yoshimura N et al. |
Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. I. Inhibition of expression of alloantigen-activated suppressor cells, as well as induction of alloreactivity. |
1989 |
Transplantation |
pmid:2465592
|
Yoshimura N et al. |
Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. II. Inhibition of the production of IL-2 and gamma-IFN, but not B cell-stimulating factor 2. |
1989 |
Transplantation |
pmid:2465593
|
Arai K et al. |
Prolonged limb allograft survival with short-term treatment with FK-506 in rats. |
1989 |
Transplant. Proc. |
pmid:2468256
|
Ishibashi M et al. |
Immunopharmacologic effects of immunosuppressive agents explored by a new effector monocyte generation assay. |
1989 |
Transplant. Proc. |
pmid:2469228
|
Starzl TE et al. |
Liver transplantation: an unfinished product. |
1989 |
Transplant. Proc. |
pmid:2469232
|
Hatanaka H et al. |
FK-506 related compounds produced by Streptomyces tsukubaensis No. 9993. |
1989 |
J. Antibiot. |
pmid:2470720
|
Gschwendt M et al. |
The immunosuppressant FK-506, like cyclosporins and didemnin B, inhibits calmodulin-dependent phosphorylation of the elongation factor 2 in vitro and biological effects of the phorbol ester TPA on mouse skin in vivo. |
1989 |
Immunobiology |
pmid:2471685
|
Fujii Y et al. |
Effect of a novel immunosuppressive agent, FK506, on mitogen-induced inositol phospholipid degradation in rat thymocytes. |
1989 |
Transplantation |
pmid:2472025
|
Tocci MJ et al. |
The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. |
1989 |
J. Immunol. |
pmid:2472451
|
Beck Y and Akiyama N |
Effect of FK-506 and cyclosporine on human lymphocyte responses in vitro. |
1989 |
Transplant. Proc. |
pmid:2472695
|
Thomson AW |
FK-506--how much potential? |
1989 |
Immunol. Today |
pmid:2473767
|
Ochiai T et al. |
Optimal serum trough levels of FK506 in renal allotransplantation of the beagle dog. |
1989 |
Transplantation |
pmid:2474208
|
Ochiai T et al. |
Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. |
1989 |
Transplantation |
pmid:2474209
|
Siekierka JJ et al. |
FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin. |
1989 |
J. Immunol. |
pmid:2474605
|
Leonard DK et al. |
Toxicity of FK-506 in human fetal pancreas. |
1989 |
Diabetes |
pmid:2463195
|
Stephen M et al. |
Immunosuppressive activity, lymphocyte subset analysis, and acute toxicity of FK-506 in the rat. A comparative and combination study with cyclosporine. |
1989 |
Transplantation |
pmid:2463701
|
McCauley J et al. |
Treatment of cyclosporin-induced haemolytic uraemic syndrome with FK506. |
1989 Dec 23-30 |
Lancet |
pmid:2481200
|
Collier SJ |
Immunosuppressive drugs. |
1989-1990 |
Curr. Opin. Immunol. |
pmid:2484794
|
Dumont FJ et al. |
Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin. |
1990 |
J. Immunol. |
pmid:1688572
|
Woo J et al. |
Immunosuppressive activity of FK-506 in rats: flow cytometric analysis of lymphocyte populations in blood, spleen and thymus during treatment and following drug withdrawal. |
1990 |
Clin. Exp. Immunol. |
pmid:1689226
|
Dumont FJ et al. |
The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells. |
1990 |
J. Immunol. |
pmid:1689353
|
Brown Z and Neild GH |
FK-506 and haemolytic uraemic syndrome. |
1990 |
Lancet |
pmid:1689442
|
Thomas J et al. |
The immunosuppressive action of FK506. In vitro induction of allogeneic unresponsiveness in human CTL precursors. |
1990 |
Transplantation |
pmid:1689518
|
Vathsala A et al. |
Analysis of the interactions of immunosuppressive drugs with cyclosporine in inhibiting DNA proliferation. |
1990 |
Transplantation |
pmid:1689520
|
Yamamoto K et al. |
Experimental treatment of autoimmune MRL-lpr/lpr mice with immunosuppressive compound FK506. |
1990 |
Immunology |
pmid:1689694
|
Thomson AW |
Interspecies comparison of the immunosuppressive efficacy and safety of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689883
|
Shapiro R et al. |
The side effects of FK 506 in humans. |
1990 |
Transplant. Proc. |
pmid:1689892
|
Van Thiel DH et al. |
Gastrointestinal and metabolic problems associated with immunosuppression with either CyA or FK 506 in liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689893
|
Mieles L et al. |
Oral glucose tolerance test in liver recipients treated with FK 506. |
1990 |
Transplant. Proc. |
pmid:1689894
|
Alessiani M et al. |
Infections with FK 506 immunosuppression: preliminary results with primary therapy. |
1990 |
Transplant. Proc. |
pmid:1689895
|
Staschak S et al. |
A cost comparison of liver transplantation with FK 506 or CyA as the primary immunosuppressive agent. |
1990 |
Transplant. Proc. |
pmid:1689896
|
|
Second International Workshop on FK 506. A potential breakthrough in immunosuppression: clinical implications. October 31, 1989, Barcelona, Spain. Proceedings. |
1990 |
Transplant. Proc. |
pmid:1689897
|
Cadoff EM et al. |
Assay of FK 506 in plasma. |
1990 |
Transplant. Proc. |
pmid:1689898
|
Venkataramanan R et al. |
Pharmacokinetics of FK 506: preclinical and clinical studies. |
1990 |
Transplant. Proc. |
pmid:1689899
|
Jain AB et al. |
Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations. |
1990 |
Transplant. Proc. |
pmid:1689900
|
Fung JJ et al. |
Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications. |
1990 |
Transplant. Proc. |
pmid:1689901
|
Zeevi A et al. |
Bioassay of plasma specimens from liver transplant patients on FK 506 immunosuppression. |
1990 |
Transplant. Proc. |
pmid:1689902
|
Imventarza O et al. |
Renal transplantation in baboons under FK 506. |
1990 |
Transplant. Proc. |
pmid:1689903
|
Monden M et al. |
A potent immunosuppressive effect of FK 506 in orthotopic liver transplantation in primates. |
1990 |
Transplant. Proc. |
pmid:1689904
|
Ericzon BG et al. |
Pancreaticoduodenal allotransplantation with FK 506 in the cynomolgus monkey. |
1990 |
Transplant. Proc. |
pmid:1689905
|
Murase N et al. |
Induction of liver, heart, and multivisceral graft acceptance with a short course of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689906
|
Hoffman AL et al. |
The effect of FK 506 on small intestine allotransplantation in the rat. |
1990 |
Transplant. Proc. |
pmid:1689907
|
Lee KK et al. |
Successful orthotopic small bowel transplantation with short-term FK 506 immunosuppressive therapy. |
1990 |
Transplant. Proc. |
pmid:1689908
|
Ueda Y et al. |
Induction of graft acceptance after dog kidney or liver transplantation. |
1990 |
Transplant. Proc. |
pmid:1689909
|
Ohara K et al. |
Toxicologic evaluation of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689910
|
Nalesnik MA et al. |
The effect of FK 506 and CyA on the Lewis rat renal ischemia model. |
1990 |
Transplant. Proc. |
pmid:1689911
|
Francavilla A et al. |
FK 506 as a growth control factor. |
1990 |
Transplant. Proc. |
pmid:1689912
|
Mazzaferro V et al. |
Studies of the hepatotrophic qualities of FK 506 and CyA. |
1990 |
Transplant. Proc. |
pmid:1689913
|
Kay JE et al. |
The mechanism of action of FK 506. |
1990 |
Transplant. Proc. |
pmid:1689914
|
Suzuki N et al. |
Effects of a novel immunosuppressive agent, FK506, on human B cell activation. |
1990 |
Clin. Exp. Immunol. |
pmid:1690097
|
McCauley J et al. |
FK 506 in steroid-resistant focal sclerosing glomerulonephritis of childhood. |
1990 |
Lancet |
pmid:1690326
|
Saitoh Y et al. |
Morphological rejection phases and cytotoxic activity in peripheral blood lymphocytes in canine lung allo-transplantation. |
1990 |
Jpn J Surg |
pmid:1692892
|
Rosen MK et al. |
Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate. |
1990 |
Science |
pmid:1693013
|
Thomas FT et al. |
Comparative efficacy of immunosuppressive drugs in xenografting. |
1990 |
Transplant. Proc. |
pmid:1693452
|
Harrison RK and Stein RL |
Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes. |
1990 |
Biochemistry |
pmid:1693856
|
Starzl TE et al. |
Kidney transplantation under FK 506. |
1990 |
JAMA |
pmid:1693970
|
Bierer BE et al. |
Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction. |
1990 |
Transplantation |
pmid:1694317
|
Eiras G et al. |
Species differences in sensitivity of T lymphocytes to immunosuppressive effects of FK 506. |
1990 |
Transplantation |
pmid:1694318
|
Tze WJ et al. |
In vitro effects of FK-506 on human and rat islets. |
1990 |
Transplantation |
pmid:1694319
|
Maki N et al. |
Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin. |
1990 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:1695378
|
Doe SE et al. |
Early effects of the immunosuppressive drug FK-506 on signal transduction in lymphocytes. |
1990 |
Biochem. Soc. Trans. |
pmid:1695581
|
Murase N et al. |
Suppression of allograft rejection with FK506. I. Prolonged cardiac and liver survival in rats following short-course therapy. |
1990 |
Transplantation |
pmid:1696405
|
Propper DJ et al. |
FK506--its influence on anti-class 1 MHC alloantibody responses to blood transfusions. |
1990 |
Transplantation |
pmid:1696409
|
Maruyama M et al. |
Effect of FK506 treatment on allocytolytic T lymphocyte induction in vivo: differential effects of FK506 on L3T4+ and Ly2+ T cells. |
1990 |
Transplantation |
pmid:1696410
|
Standaert RF et al. |
Molecular cloning and overexpression of the human FK506-binding protein FKBP. |
1990 |
Nature |
pmid:1696686
|
Tropschug M et al. |
Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding. |
1990 |
Nature |
pmid:1696687
|
Randall T |
New antirejection drugs anticipated. |
1990 |
JAMA |
pmid:1696999
|
Metcalfe S et al. |
FK 506 and cyclosporine A: early effects on activation and gene induction in mouse spleen cells. |
1990 |
Transplant. Proc. |
pmid:1697107
|
Morris RE et al. |
A study of the contrasting effects of cyclosporine, FK 506, and rapamycin on the suppression of allograft rejection. |
1990 |
Transplant. Proc. |
pmid:1697111
|
Woo J et al. |
Flow cytometric analysis of lymphocyte populations and activation antigen expression in blood and lymphoid tissues of FK 506-treated rats. |
1990 |
Transplant. Proc. |
pmid:1697112
|
Woo J et al. |
Effects of FK 506 and low concentration cyclosporine on human lymphocyte activation antigen expression: a flow cytometric analysis. |
1990 |
Transplant. Proc. |
pmid:1697113
|
Propper DJ et al. |
Low-dose FK 506 inhibits sensitisation after blood transfusions. |
1990 |
Transplant. Proc. |
pmid:1697114
|
Tiebosch A et al. |
Side effects of FK 506 in cynomolgus monkeys: a histopathologic study. |
1990 |
Transplant. Proc. |
pmid:1697115
|
Dammeijer PF et al. |
Combined effect of low-dose FK 506 and cyclosporine A on skin graft survival. |
1990 |
Transplant. Proc. |
pmid:1697116
|
Imai K et al. |
Pancreaticoduodenal allotransplantation with the use of FK 506, cyclosporine, and triple-regimen immunosuppression. |
1990 |
Transplant. Proc. |
pmid:1697117
|
Iga C et al. |
Prolonged survival of small intestinal allograft in the rat with cyclosporine A, FK 506, and 15-deoxyspergualin. |
1990 |
Transplant. Proc. |
pmid:1697118
|
Lagodzinski Z et al. |
Effect of FK506 and cyclosporine on primary and secondary skin allograft survival in mice. |
1990 |
Immunology |
pmid:1698713
|
Isai H et al. |
FK 506 and orthotopic liver transplantation in the rat. |
1990 |
Transplant. Proc. |
pmid:1699329
|
Suzuki S et al. |
In vivo 31P nuclear magnetic resonance findings on heterotopically allografted hearts in rats treated with a novel immunosuppressant, FK506. |
1990 |
Heart Vessels |
pmid:1699922
|
Bierer BE et al. |
Probing immunosuppressant action with a nonnatural immunophilin ligand. |
1990 |
Science |
pmid:1700475
|
Murase N et al. |
FK506 suppression of heart and liver allograft rejection. II: The induction of graft acceptance in rats. |
1990 |
Transplantation |
pmid:1700504
|
Burke MD et al. |
Inhibition of the metabolism of cyclosporine by human liver microsomes by FK506. |
1990 |
Transplantation |
pmid:1700507
|
Wicker LS et al. |
Suppression of B cell activation by cyclosporin A, FK506 and rapamycin. |
1990 |
Eur. J. Immunol. |
pmid:1700753
|
Sigal NH et al. |
Observations on the mechanism of action of FK-506. A pharmacologic probe of lymphocyte signal transduction. |
1990 |
Biochem. Pharmacol. |
pmid:1700909
|
Hara S et al. |
The effects of a new immunosuppressive agent, FK506, on the glomerular injury in rats with accelerated nephrotoxic serum glomerulonephritis. |
1990 |
Clin. Immunol. Immunopathol. |
pmid:1700936
|
Murase N et al. |
Effect of FK 506 on spontaneous diabetes in BB rats. |
1990 |
Diabetes |
pmid:1700959
|
Kawashima H and Mochizuki M |
Effects of a new immunosuppressive agent, FK 506, on the efferent limb of the immune responses. |
1990 |
Exp. Eye Res. |
pmid:1701148
|
Siekierka JJ et al. |
The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase. |
1990 |
J. Biol. Chem. |
pmid:1701173
|
Johansson A and Möller E |
Evidence that the immunosuppressive effects of FK506 and cyclosporine are identical. |
1990 |
Transplantation |
pmid:1701570
|
Reyes J et al. |
Expressive dysphasia possibly related to FK506 in two liver transplant recipients. |
1990 |
Transplantation |
pmid:1701571
|
Tsuji RF et al. |
Selective immunosuppression of prodigiosin 25-C and FK506 in the murine immune system. |
1990 |
J. Antibiot. |
pmid:1701765
|
Granelli-Piperno A et al. |
The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter. |
1990 |
J. Exp. Med. |
pmid:1701825
|
Lee KK et al. |
Comparison of short-term immunosuppressive therapy with cyclosporine and FK 506 in small-bowel transplantation. |
1990 |
Transplant. Proc. |
pmid:1702239
|
Takai K et al. |
Effects of FK506 on rat thymus: time-course analysis by immunoperoxidase technique and flow cytofluorometry. |
1990 |
Clin. Exp. Immunol. |
pmid:1702372
|
Okubo Y et al. |
FK506, a novel immunosuppressive agent, induces antigen-specific immunotolerance in active Heymann's nephritis and in the autologous phase of Masugi nephritis. |
1990 |
Clin. Exp. Immunol. |
pmid:1702373
|
Arita C et al. |
Inhibition by FK506 of established lesions of collagen-induced arthritis in rats. |
1990 |
Clin. Exp. Immunol. |
pmid:1702374
|
Akutsu I et al. |
[Inhibitory effect of FK-506 on the development of late asthmatic response and on the increased bronchial responsiveness]. |
1990 |
Arerugi |
pmid:1705791
|
Pugh-Humphreys RG et al. |
The influence of FK-506 on the thymus: an immunophenotypic and structural analysis. |
1990 |
Immunology |
pmid:1696242
|
Mochizuki M and Kawashima H |
Effects of FK506, 15-deoxyspergualin, and cyclosporine on experimental autoimmune uveoretinitis in the rat. |
1990 |
Autoimmunity |
pmid:1717007
|
Ni M et al. |
FR900506 (FK506) and 15-deoxyspergualin (15-DSG) modulate the kinetics of infiltrating cells in eyes with experimental autoimmune uveoretinitis. |
1990 |
Autoimmunity |
pmid:1717008
|