| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lichen Nitidus | D017513 | 1 associated lipids |
| Feline Infectious Peritonitis | D016766 | 1 associated lipids |
| Meningitis, Cryptococcal | D016919 | 1 associated lipids |
| Oculomotor Nerve Diseases | D015840 | 1 associated lipids |
| Cutis Laxa | D003483 | 1 associated lipids |
| Invasive Pulmonary Aspergillosis | D055744 | 1 associated lipids |
| Intestinal Volvulus | D045822 | 1 associated lipids |
| Hand Injuries | D006230 | 1 associated lipids |
| Beckwith-Wiedemann Syndrome | D001506 | 1 associated lipids |
| Eye Diseases, Hereditary | D015785 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jordan ML et al. | Tacrolimus for rescue of refractory renal allograft rejection. | 1998 | Transplant. Proc. | pmid:9636511 |
| Undre NA and Schäfer A | Factors affecting the pharmacokinetics of tacrolimus in the first year after renal transplantation. European Tacrolimus Multicentre Renal Study Group. | 1998 | Transplant. Proc. | pmid:9636512 |
| Uchida J et al. | Effects of conversion from a twice-daily tacrolimus to a once-daily tacrolimus on glucose metabolism in stable kidney transplant recipients. | 2014 | Transplant. Proc. | pmid:24656005 |
| Weng LC et al. | Association between use of FK506 and prevalence of post-transplantation diabetes mellitus in kidney transplant patients. | 2014 | Transplant. Proc. | pmid:24656004 |
| Wang SS et al. | Clinical experience of tacrolimus with everolimus in heart transplantation. | 2012 | Transplant. Proc. | pmid:22564581 |
| Sewing KF | Pharmacokinetics, dosing principles, and blood level monitoring of FK506. | 1994 | Transplant. Proc. | pmid:7527962 |
| Youhua Z et al. | Clinical study of FK 506 in renal transplant recipients. | 2000 | Transplant. Proc. | pmid:11119900 |
| Klintmalm GB et al. | Prognostic factors for successful conversion from cyclosporine to FK 506-based immunosuppressive therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group. | 1993 | Transplant. Proc. | pmid:7679828 |
| Venkataramanan R et al. | Pharmacokinetics of FK 506 in transplant patients. | 1991 | Transplant. Proc. | pmid:1721261 |
| Washburn WK et al. | Tacrolimus rescue therapy for renal allograft rejection refractory to cyclosporine-based immunosuppression. | 1996 | Transplant. Proc. | pmid:8623214 |
| Second International Workshop on FK 506. A potential breakthrough in immunosuppression: clinical implications. October 31, 1989, Barcelona, Spain. Proceedings. | 1990 | Transplant. Proc. | pmid:1689897 | |
| Shitrit D et al. | Tacrolimus-induced hemolytic uremic syndrome case presentation in a lung transplant recipient. | 2003 | Transplant. Proc. | pmid:12644073 |
| Crespo-Leiro MG et al. | Replacement of cyclosporine by tacrolimus for immunosuppression in heart transplant patients: safety and efficacy. | 2002 | Transplant. Proc. | pmid:11959213 |
| Stringa P et al. | Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice. | 2013 Jul-Aug | Transplant. Proc. | pmid:23953566 |
| Osuna A et al. | Two doses of daclizumab with delayed introduction of low-dose tacrolimus in elderly recipients of cadaveric renal transplants from donors >55 years of age. | 2005 | Transplant. Proc. | pmid:15866630 |
| Gentil MA et al. | Effect of new immunosuppressive regimens on cost of renal transplant maintenance immunosuppression. | 2005 | Transplant. Proc. | pmid:15866631 |
| Ringe B et al. | Tacrolimus and mycophenolate mofetil in clinical liver transplantation: experience with a steroid-sparing concept. | 1998 | Transplant. Proc. | pmid:9636573 |
| Pascual J et al. | Interaction between omeprazole and tacrolimus in renal allograft recipients: a clinical-analytical study. | 2005 | Transplant. Proc. | pmid:16386527 |
| Garcia-Donaire JA et al. | Tacrolimus as basic immunosuppression in pregnancy after renal transplantation. A single-center experience. | 2005 | Transplant. Proc. | pmid:16386528 |
| Argudo A et al. | Liver Transplant Patient Carriers of Polymorphism Cyp3a5*1 Donors May Need More Doses of Tacrolimus From the First Month After Transplantation. | 2015 | Transplant. Proc. | pmid:26518936 |
| Cuñetti L et al. | Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. | 2018 | Transplant. Proc. | pmid:29579828 |
| Moriuchi H et al. | Mechanisms of immunosuppressive effects of FK 506 in light of apoptosis of hepatocytes and infiltrating lymphocytes in rat allografted livers. | 2000 | Transplant. Proc. | pmid:11120182 |
| Tashiro H et al. | Donor bone marrow perioperatively administered via portal vein induced prolongation of skin allograft survival and microchimerism in liver-transplanted rats. | 2000 | Transplant. Proc. | pmid:11120201 |
| Akselband Y et al. | Rapamycin inhibits spontaneous and fibroblast growth factor beta-stimulated proliferation of endothelial cells and fibroblasts. | 1991 | Transplant. Proc. | pmid:1721292 |
| Jurewicz WA | Immunological and nonimmunological risk factors with tacrolimus and Neoral in renal transplant recipients: an interim report. | 1999 | Transplant. Proc. | pmid:10576048 |
| Schreiber SL et al. | Immunophilin-ligand complexes as probes of intracellular signaling pathways. | 1991 | Transplant. Proc. | pmid:1721293 |
| Klintmalm GB | Clinical use of FK 506 in liver transplantation. | 1996 | Transplant. Proc. | pmid:8623484 |
| Butt TR et al. | Molecular basis of immunosuppressive drug action: regulation of steroid receptor-mediated transcription by FK 506. | 1996 | Transplant. Proc. | pmid:8623486 |
| Burg M et al. | Enteric-coated mycophenolate sodium reduces gastrointestinal symptoms in renal transplant patients. | 2009 | Transplant. Proc. | pmid:20005359 |
| Falkiewicz K et al. | Influence of vitamin D receptor gene polymorphisms on secondary hyperparathyroidism and bone density after kidney transplantation. | 2005 | Transplant. Proc. | pmid:15848611 |
| Schneeberger H et al. | Tacrolimus as a primary immunosuppressive therapy in cadaveric renal transplantation: five years' experience at a single center. | 1998 | Transplant. Proc. | pmid:9636642 |
| Kantarci G et al. | Effects of different calcineurin inhibitors on sex hormone levels in transplanted male patients. | 2004 Jan-Feb | Transplant. Proc. | pmid:15013339 |
| Yamazaki R et al. | Interindividual variation of maximal blood levels of tacrolimus after its oral administration in hematopoietic cell transplant recipients. | 2009 | Transplant. Proc. | pmid:19545738 |
| Kolonko A et al. | Improved kidney graft function after conversion from twice daily tacrolimus to a once daily prolonged-release formulation. | 2011 | Transplant. Proc. | pmid:21996198 |
| Gavlik A et al. | Mycophenolate mofetil rescue therapy in liver transplant recipients: an extended follow-up. | 1997 | Transplant. Proc. | pmid:9365633 |
| Spada M et al. | Morphology of acute rejection and observation of lymphoproliferative hyperplastic reaction in FK 506 treated pigs after small bowel transplantation. | 1994 | Transplant. Proc. | pmid:7518142 |
| Foroncewicz B et al. | Anti-CD25 and tacrolimus therapy may not prevent early primary biliary cirrhosis recurrence after liver transplantation: two case reports. | 2003 | Transplant. Proc. | pmid:14529924 |
| Kai N et al. | A study on the timing of immunologic priming in autoimmune insulitis in NOD mice. | 1992 | Transplant. Proc. | pmid:1376511 |
| Langrehr JM et al. | Liver transplantation in hepatitis B surface antigen positive patients with postoperative long-term immunoprophylaxis. | 1995 | Transplant. Proc. | pmid:7533373 |
| Kim SW et al. | Decreased formation of nitric oxide in rats treated with FK506. | 2003 | Transplant. Proc. | pmid:12591357 |
| Nakata S et al. | Immunosuppressive effect of FK 506 on cytotoxic T lymphocytes and delayed-type hypersensitivity in rats. | 1991 | Transplant. Proc. | pmid:1721325 |
| Daly I et al. | Mycophenolate mofetil for treatment of chronic rejection in liver allograft under tacrolimus. | 2002 | Transplant. Proc. | pmid:12176458 |
| Wilson C et al. | Evaluation of daclizumab to reduce delayed graft function in non-heart-beating renal transplantation: a prospective, randomized trial. | 2005 | Transplant. Proc. | pmid:15919462 |
| Tsuchida Y et al. | Vascularized bone marrow allotransplantation in rats prolongs a simultaneous skin allograft. | 1997 | Transplant. Proc. | pmid:9142252 |
| Ciftci HS et al. | Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism. | 2017 | Transplant. Proc. | pmid:28340819 |
| Fontana I et al. | Severe rhabdomyolysis and acute renal failure in a kidney transplant patient treated with tacrolimus and chimaeric CD25 monoclonal antibody. | 2004 | Transplant. Proc. | pmid:15110640 |
| Shapiro R et al. | A prospective, randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone in renal transplant patients. | 1995 | Transplant. Proc. | pmid:7533432 |
| Winkler M et al. | Comparison of plasma vs whole blood as matrix for FK 506 drug level monitoring. | 1995 | Transplant. Proc. | pmid:7533433 |
| Whiteside TL et al. | Serial monitoring of immunologic function and phenotype of lymphocytes in the blood of transplanted patients randomized to cyclosporine or FK 506. | 1991 | Transplant. Proc. | pmid:1721356 |
| Van Thiel DH et al. | Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine. | 1991 | Transplant. Proc. | pmid:1721357 |
| Dahmen U et al. | Onset of liver regeneration after subtotal resection is inhibited by the use of new immunosuppressive drugs. | 2002 | Transplant. Proc. | pmid:12270412 |
| Takahara S et al. | Excellent results following 3 years of tacrolimus immunosuppression in kidney transplantation recipients in Japan: overall analysis of more than 1000 patients. | 2002 | Transplant. Proc. | pmid:12176500 |
| Jabiry-Zieniewicz Z et al. | Outcome of four high-risk pregnancies in female liver transplant recipients on tacrolimus immunosuppression. | 2006 Jan-Feb | Transplant. Proc. | pmid:16504718 |
| Lo CM et al. | Use of FK506 as primary or rescue therapy after liver transplantation in Hong Kong. | 1998 | Transplant. Proc. | pmid:9838571 |
| Reichenspurner H et al. | Tacrolimus-based immunosuppressive protocols in lung transplantation. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083062 |
| Khanna A et al. | Cardiac changes at autopsy in adult liver transplant recipients under tacrolimus. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123118 |
| Alper G and Small SL | Cerebrospinal fluid after organ transplantation. | 1996 | Transplant. Proc. | pmid:8908142 |
| Sahutoglu T et al. | Tac-MMF Versus CsA-MMF/CsA-AZA-Based Regimens in Development of De Novo Complement-Binding Anti-HLA Antibodies After Kidney Transplantation. | 2017 | Transplant. Proc. | pmid:28340811 |
| Marcus EA et al. | Successful term pregnancy in an intestine-pancreas transplant recipient with chronic graft dysfunction and parenteral nutrition dependence: a case report. | 2015 | Transplant. Proc. | pmid:25724255 |
| Takagishi K et al. | Effects of FK-506 on collagen arthritis in mice. | 1989 | Transplant. Proc. | pmid:2468205 |
| Schmidt RJ et al. | Hemolytic-uremic syndrome in a renal transplant recipient on FK 506 immunosuppression. | 1991 | Transplant. Proc. | pmid:1721390 |
| Paul LC | Overview of side effects of immunosuppressive therapy. | 2001 | Transplant. Proc. | pmid:11377462 |
| Rodrigo E et al. | Histopathological findings according to Banff-97 classification system comparing tacrolimus versus cyclosporine. | 2002 | Transplant. Proc. | pmid:12176550 |
| Ierardi E et al. | Long-term tacrolimus: a promising therapeutic approach for Crohn's disease. | 2001 | Transplant. Proc. | pmid:11377467 |
| Jørgensen KA et al. | Two-hour blood tacrolimus levels are not superior to trough levels as estimates of the area under the curve in tacrolimus-treated renal transplant patients. | 2002 | Transplant. Proc. | pmid:12176551 |
| Castel MA et al. | Primary immunosuppression and outcome differences after heart transplantation: tacrolimus versus cyclosporine. | 2011 Jul-Aug | Transplant. Proc. | pmid:21839245 |
| Elinav H et al. | Plasma oxidizability and plasma carbonyls, markers of oxidative stress, in liver transplant patients. | 2001 | Transplant. Proc. | pmid:11543789 |
| Mor E et al. | Homocysteine levels among transplant recipients: effect of immunosuppressive protocols. | 2001 | Transplant. Proc. | pmid:11543802 |
| Kokado Y et al. | Low-dose tacrolimus (FK 506)-based immunosuppressive protocol in living donor renal transplantation. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083515 |
| Saracino A et al. | Multidrug-resistance 1 gene single-nucleotide polymorphisms do not influence long-term graft survival after kidney transplantation. | 2014 | Transplant. Proc. | pmid:25242754 |
| Matsumiya G et al. | Serum interleukin-6 level after cardiac xenotransplantation in primates. | 1997 Feb-Mar | Transplant. Proc. | pmid:9123586 |
| Bhagavati S et al. | Chronic sensorimotor polyneuropathy associated with tacrolimus immunosuppression in renal transplant patients: case reports. | 2007 | Transplant. Proc. | pmid:18089409 |
| Meloni F et al. | Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection. | 2003 | Transplant. Proc. | pmid:12826211 |
| Boggs S et al. | FK 506 has no short-term effects on endogenous or exogenous myeloid reconstitution in irradiated mice. | 1991 | Transplant. Proc. | pmid:1721420 |
| Ogawa N et al. | Suppressive effects of combination therapy with mizoribine and FK 506 on the development of accelerated coronary artery disease and myocardial rejection after heart transplantation. | 1996 | Transplant. Proc. | pmid:8658710 |
| Soran A et al. | Renal retransplantation in elderly recipients under tacrolimus-based immunosuppression. | 2000 | Transplant. Proc. | pmid:10812157 |
| Formica RN et al. | Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation. | 2003 | Transplant. Proc. | pmid:12742475 |
| Hasegawa A et al. | Optimal use of tacrolimus in living donor renal transplantation in children. | 2002 | Transplant. Proc. | pmid:12176635 |
| van den Berg AP et al. | Prediction of the inhibition of IL-2 production by calcineurin inhibitors. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267197 |
| Koc-Zorawska E et al. | Vascular adhesion protein-1, a novel molecule, in kidney and heart allograft recipients. | 2013 | Transplant. Proc. | pmid:23769096 |
| Alessiani M et al. | Effect of perioperative donor bone marrow infusion after small bowel transplantation in swine: preliminary results. | 1998 | Transplant. Proc. | pmid:9745496 |
| Otto C et al. | Selective immunosuppression with FK 506, anti-IL-2R, and anti-ICAM-1 monoclonal antibodies: contrasting effects after liver and small bowel transplantation in rats. | 1998 | Transplant. Proc. | pmid:9723426 |
| Chen H et al. | Combined effect of rapamycin and FK 506 in prolongation of small bowel graft survival in the mouse. | 1998 | Transplant. Proc. | pmid:9745497 |
| Ott R et al. | Does conversion of immunosuppressive monotherapy from cyclosporine A to tacrolimus improve bone mineral density in long-term stable liver transplant recipients? | 2003 | Transplant. Proc. | pmid:14697971 |
| Abu-Elmagd K et al. | Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum. | 1991 | Transplant. Proc. | pmid:1721451 |
| Thomson AW et al. | Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study. | 1991 | Transplant. Proc. | pmid:1721452 |
| Immunosuppression: FK506. | 1988 | Transplant. Proc. | pmid:2450415 | |
| Todo S et al. | Effect of FK506 in experimental organ transplantation. | 1988 | Transplant. Proc. | pmid:2450416 |
| Hirata Y et al. | Antibody Drug Treatment for Steroid-Resistant Rejection After Pediatric Living Donor Liver Transplantation: A Single-Center Experience. | Transplant. Proc. | pmid:29407332 | |
| Falconer SJ et al. | Early or Late Conversion From Tac-BD to Tac-BD in Renal Transplantation: When is the Right Time? | Transplant. Proc. | pmid:26293044 | |
| Shi G et al. | Variation of CD4CD25Foxp3 Regulatory T Cells and Th17 Cells in the Peripheral Blood of Human Liver Allograft Patients With Long-term Survival. | 2017 | Transplant. Proc. | pmid:28923634 |
| Treede H et al. | Incidence and spectrum of infections in lung transplanted patients: comparison of four different immunosuppressive protocols. | 2001 Feb-Mar | Transplant. Proc. | pmid:11267444 |
| Chen H et al. | FK 506 and rapamycin in combination are not antagonistic but produce extended small bowel graft survival in the mouse. | 1998 | Transplant. Proc. | pmid:9636419 |
| Sessa A et al. | Cardiovascular risk factors in renal transplant patients after switch from standard tacrolimus to prolonged-release tacrolimus. | 2012 | Transplant. Proc. | pmid:22974866 |
| Duzova A et al. | Triple immunosuppression with tacrolimus in pediatric renal transplantation: single-center experience. | 2008 Jan-Feb | Transplant. Proc. | pmid:18261567 |
| Alagoz S et al. | Gangliocytoma Presenting With Tacrolimus Neurotoxicity in a Renal Transplant Recipient: Case Report. | 2016 | Transplant. Proc. | pmid:27932167 |
| Yoshimura R et al. | A comparative study between cyclosporine and FK 506 effects on renal microsomal P-450. | 1991 | Transplant. Proc. | pmid:1703686 |
| Deleuze S et al. | New onset dyslipidemia after renal transplantation: is there a difference between tacrolimus and cyclosporine? | 2006 | Transplant. Proc. | pmid:16980075 |
| Lawen J et al. | Sirolimus and low-dose tacrolimus with antibody induction in kidney transplantation: preliminary results of a pilot study. | 2001 Nov-Dec | Transplant. Proc. | pmid:11750382 |
| Hartwig T et al. | Low-dose sirolimus and tacrolimus in kidney transplantation: first results of a single-center experience. | 2001 Nov-Dec | Transplant. Proc. | pmid:11750383 |