| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mediastinal Emphysema | D008478 | 1 associated lipids |
| Malacoplakia | D008287 | 1 associated lipids |
| Myoclonic Cerebellar Dyssynergia | D002527 | 1 associated lipids |
| Lichen Nitidus | D017513 | 1 associated lipids |
| Lichenoid Eruptions | D017512 | 1 associated lipids |
| Lymphocele | D008210 | 1 associated lipids |
| Colitis, Collagenous | D046729 | 1 associated lipids |
| Hand Injuries | D006230 | 1 associated lipids |
| Beckwith-Wiedemann Syndrome | D001506 | 1 associated lipids |
| Eye Diseases, Hereditary | D015785 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fruman DA et al. | The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. | 1995 | J. Immunol. | pmid:7530743 |
| Neuhaus P et al. | Comparison of FK506- and cyclosporine-based immunosuppression in primary orthotopic liver transplantation. A single center experience. | 1995 | Transplantation | pmid:7530868 |
| Heeckt PF et al. | Functional impairment of enteric smooth muscle and nerves caused by chronic intestinal allograft rejection regresses after FK506 rescue. | 1995 | Transplantation | pmid:7530870 |
| Gruessner RW et al. | A prospective study of FK506 versus CsA and pig ATG in a porcine model of small bowel transplantation. | 1995 | Transplantation | pmid:7530871 |
| Todo S et al. | Abdominal multivisceral transplantation. | 1995 | Transplantation | pmid:7530873 |
| Cameron AM et al. | Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7533300 |
| Shapiro R et al. | A prospective randomized trial of FK506-based immunosuppression after renal transplantation. | 1995 | Transplantation | pmid:7533343 |
| Cox KL et al. | An increased incidence of Epstein-Barr virus infection and lymphoproliferative disorder in young children on FK506 after liver transplantation. | 1995 | Transplantation | pmid:7533344 |
| McDiarmid SV et al. | FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial. | 1995 | Transplantation | pmid:7533345 |
| Jain AB et al. | One thousand consecutive primary orthotopic liver transplants under FK 506: survival and adverse events. | 1995 | Transplant. Proc. | pmid:7533353 |
| Grobecker HF et al. | Cyclosporine A-induced hypertension in SHR and WKY: role of the sympatho-adrenal system. | 1995 | Clin Exp Pharmacol Physiol Suppl | pmid:9072458 |
| Tsugita M et al. | Prevention of sensitization and hyperacute rejection in liver and heart xenografts by FK 506 plus donor antigens. | 1995 | Transplant. Proc. | pmid:7533393 |
| Sakimoto H et al. | Prolonged survival of hamster-to-rat pancreas xenografts by FK 506 and splenectomy. | 1995 | Transplant. Proc. | pmid:7533394 |
| Celli S et al. | Mechanisms of protection from humoral rejection by a xenografted liver. | 1995 | Transplant. Proc. | pmid:7533395 |
| Kuroki H and Ikuta Y | Nerve regeneration of vascularized rat limb allograft and functional recovery of long-term graft survivals treated by short course of FK 506 or cyclosporine. | 1995 | Transplant. Proc. | pmid:7533405 |
| Ko S et al. | Significance of newly developed liposomal FK 506 in canine liver transplantation. | 1995 | Transplant. Proc. | pmid:7533406 |
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| Hodgkiss JP and Kelly JS | Only 'de novo' long-term depression (LTD) in the rat hippocampus in vitro is blocked by the same low concentration of FK506 that blocks LTD in the visual cortex. | 1995 | Brain Res. | pmid:8821755 |
| Cunningham EB | The human erythrocyte membrane contains a novel 12-kDa inositolphosphate-binding protein that is an immunophilin. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7575593 |
| Ellis D | Clinical use of tacrolimus (FK-506) in infants and children with renal transplants. | 1995 | Pediatr. Nephrol. | pmid:7577418 |
| Furuke K et al. | Suppression of adult T cell leukemia-derived factor/human thioredoxin induction by FK506 and cyclosporin A: a new mechanism of immune modulation via redox control. | 1995 | Int. Immunol. | pmid:7577807 |
| Suzuki H et al. | Spleen grafting might induce transplantation tolerance in rats. | 1995 | Transplant. Proc. | pmid:7536973 |
| Shapiro R et al. | FK506 in pediatric kidney transplantation--primary and rescue experience. | 1995 | Pediatr. Nephrol. | pmid:7492486 |
| Mehta BA et al. | Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells. | 1995 | Blood | pmid:7579455 |
| Ito A et al. | Induction of tolerance in rat cardiac allograft model by intrathymic injection of donor bone marrow cells. | 1995 | Transplant. Proc. | pmid:7536974 |
| Coss MC et al. | Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65). | 1995 | J. Biol. Chem. | pmid:7493967 |
| Büttemeyer R et al. | Peripheral nerve allotransplant immunosuppressed with FK 506: preliminary results. | 1995 | Transplant. Proc. | pmid:7536979 |
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| Prud'homme GJ et al. | Effects of cyclosporin A, rapamycin, and FK520 on peripheral T-cell deletion and anergy. | 1995 | Cell. Immunol. | pmid:7543371 |
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| Rodriguez Rilo HL et al. | Rapid hair regrowth in refractory alopecia universalis associated with autoimmune disease following liver transplantation and tacrolimus (FK506) therapy. | 1995 | Transplantation | pmid:7539169 |
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| Fealy MJ et al. | Association of down-regulation of cytokine activity with rat hind limb allograft survival. | 1995 | Transplantation | pmid:7539555 |
| Hibi S et al. | Severe rhabdomyolysis associated with tacrolimus. | 1995 | Lancet | pmid:7544861 |
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| Systemic tacrolimus (FK 506) is effective for the treatment of psoriasis in a double-blind, placebo-controlled study. The European FK 506 Multicentre Psoriasis Study Group. | 1996 | Arch Dermatol | pmid:8629845 | |
| Osowski CL et al. | Evaluation of the drug interaction between intravenous high-dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients. | 1996 | Transplantation | pmid:8610430 |
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| Laskow DA et al. | An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group. | 1996 | Transplantation | pmid:8878381 |
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