| MeSH term | MeSH ID | Detail |
|---|---|---|
| Intestinal Volvulus | D045822 | 1 associated lipids |
| Hand Injuries | D006230 | 1 associated lipids |
| Beckwith-Wiedemann Syndrome | D001506 | 1 associated lipids |
| Eye Diseases, Hereditary | D015785 | 1 associated lipids |
| Hepatopulmonary Syndrome | D020065 | 1 associated lipids |
| Herpes Labialis | D006560 | 1 associated lipids |
| End Stage Liver Disease | D058625 | 1 associated lipids |
| Nocturnal Myoclonus Syndrome | D020189 | 1 associated lipids |
| Uveomeningoencephalitic Syndrome | D014607 | 1 associated lipids |
| Myelitis | D009187 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Watanabe K et al. | Fate of long-surviving allografts in tolerant recipients induced by fractionated lymphoid irradiation, donor bone marrow cell infusion, and FK 506 after retransplantation in dogs. | 1993 | Transplant. Proc. | pmid:7679813 |
| Valdivia LA et al. | Hamster-to-rat liver xenografts protect extrahepatic organs from rejection. | 1993 | Transplant. Proc. | pmid:7679816 |
| Murase N et al. | Effect of FK 506 and antiproliferative agents for heart and liver xenotransplantation from hamster to rat. | 1993 | Transplant. Proc. | pmid:7679817 |
| Schreier MH et al. | Inhibition of T-cell signaling pathways by immunophilin drug complexes: are side effects inherent to immunosuppressive properties? | 1993 | Transplant. Proc. | pmid:7679818 |
| Kahan BD | Cyclosporine: the base for immunosuppressive therapy--present and future. | 1993 | Transplant. Proc. | pmid:7679819 |
| Fung J et al. | Randomized trial in primary liver transplantation under immunosuppression with FK 506 or cyclosporine. | 1993 | Transplant. Proc. | pmid:7680146 |
| Shibata T et al. | Does FK 506 accelerate the development of coronary artery disease in the transplanted heart as well as the native heart? | 1993 | Transplant. Proc. | pmid:7680147 |
| Todo S et al. | Intestinal transplantation in humans under FK 506. | 1993 | Transplant. Proc. | pmid:7680148 |
| Reyes J et al. | Nutritional management of intestinal transplant recipients. | 1993 | Transplant. Proc. | pmid:7680149 |
| Abu-Elmagd KM et al. | Monitoring and treatment of intestinal allograft rejection in humans. | 1993 | Transplant. Proc. | pmid:7680150 |
| McCauley J et al. | FK 506 in the management of nephrotic syndrome after renal transplantation. | 1993 | Transplant. Proc. | pmid:7680154 |
| Takahara S et al. | [Blood level monitoring of FK506 on kidney transplant recipients]. | 1993 | Nippon Hinyokika Gakkai Zasshi | pmid:7504758 |
| Lieberman I et al. | Synergy between tetrandrine and FK506 in prevention of diabetes in BB rats. | 1993 | Life Sci. | pmid:7504774 |
| Müller MK et al. | [Pathophysiologic concepts and protective possibilities in experimental pancreatic lesions]. | 1993 | Z Gastroenterol | pmid:7504856 |
| Panis Y and Valleur P | [Small intestine transplantation. Experimental and clinical results]. | 1993 | Ann Chir | pmid:7504899 |
| Bruserud O and Pawelec G | Cyclosporine A and FK506 show similar immunosuppressive effects on long-term in vitro T-cell proliferation. | 1993 | Int. J. Immunopharmacol. | pmid:7682202 |
| Tsai M et al. | Activation of MAP kinases, pp90rsk and pp70-S6 kinases in mouse mast cells by signaling through the c-kit receptor tyrosine kinase or Fc epsilon RI: rapamycin inhibits activation of pp70-S6 kinase and proliferation in mouse mast cells. | 1993 | Eur. J. Immunol. | pmid:7504992 |
| Winkler M et al. | Anaemia associated with FK 506 immunosuppression. | 1993 | Lancet | pmid:7682273 |
| Lundemose AG et al. | Chlamydia trachomatis Mip-like protein has peptidyl-prolyl cis/trans isomerase activity that is inhibited by FK506 and rapamycin and is implicated in initiation of chlamydial infection. | 1993 | Mol. Microbiol. | pmid:7682281 |
| Wiesner RH et al. | Early cellular rejection treated with high-dose intravenous corticosteroid therapy is associated with a decrease in the incidence of steroid-resistant rejection and graft failure from rejection. | 1993 | Transplant. Proc. | pmid:7682352 |
| Frank B et al. | Neurotoxicity of FK 506 in liver transplant recipients. | 1993 | Transplant. Proc. | pmid:7682355 |
| McDiarmid SV et al. | FK506 conversion for intractable rejection of the liver allograft. | 1993 | Transpl. Int. | pmid:7507675 |
| Akita K and Mandel TE | Effect of FK 506 and anti-CD4 monoclonal antibody treatment on xenografts of organ-cultured fetal pig pancreas and host lymphoid populations. | 1993 | Transplant. Proc. | pmid:7692650 |
| Tokunaga Y et al. | Living related liver transplantation across ABO blood groups with FK506 and OKT3. | 1993 | Transpl. Int. | pmid:7507676 |
| Liu J | FK506 and ciclosporin: molecular probes for studying intracellular signal transduction. | 1993 | Trends Pharmacol. Sci. | pmid:7692652 |
| David M et al. | [Changes in cervix cytology in women with liver transplants treated with immunosuppressive therapy]. | 1993 | Zentralbl Gynakol | pmid:7692689 |
| Wallemacq PE and Reding R | FK506 (tacrolimus), a novel immunosuppressant in organ transplantation: clinical, biomedical, and analytical aspects. | 1993 | Clin. Chem. | pmid:7693372 |
| Nakamura T et al. | Protein phosphatase type 2B (calcineurin)-mediated, FK506-sensitive regulation of intracellular ions in yeast is an important determinant for adaptation to high salt stress conditions. | 1993 | EMBO J. | pmid:7693452 |
| Wiederrecht G et al. | The mechanism of action of FK-506 and cyclosporin A. | 1993 | Ann. N. Y. Acad. Sci. | pmid:7509138 |
| Morikawa K et al. | Immunosuppressive activity of fosfomycin on human T-lymphocyte function in vitro. | 1993 | Antimicrob. Agents Chemother. | pmid:7509146 |
| Schwaninger M et al. | The immunosuppressive drugs cyclosporin A and FK506 inhibit calcineurin phosphatase activity and gene transcription mediated through the cAMP-responsive element in a nonimmune cell line. | 1993 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:7509460 |
| Shapiro R et al. | FK 506 interaction with danazol. | 1993 | Lancet | pmid:7684106 |
| Becker JW et al. | FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. | 1993 | J. Biol. Chem. | pmid:7684380 |
| Dickey JB et al. | Periocular FK-506 delays allograft rejection in rat penetrating keratoplasty. | 1993 | Cornea | pmid:7684663 |
| Francavilla A et al. | Hepatic regeneration and growth factors. | 1993 | J Surg Oncol Suppl | pmid:7684910 |
| Connelly PR et al. | Probing hydration contributions to the thermodynamics of ligand binding by proteins. Enthalpy and heat capacity changes of tacrolimus and rapamycin binding to FK506 binding protein in D2O and H2O. | 1993 | Biochemistry | pmid:7684925 |
| Thomson AW et al. | Effects of combined administration of FK 506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T cell activation molecule expression in human mixed lymphocyte cultures. | 1993 | Transpl. Immunol. | pmid:7521738 |
| Matsuura T et al. | Organ-specific unresponsiveness induced by intrathymic injection of donor bone marrow cells and a short course of immunosuppression in the rat heart transplantation model. | 1993 | Transpl. Immunol. | pmid:7521742 |
| Fujisawa T et al. | Dose study of the immunosuppression of FK 506 in canine lung allo-transplantation. | 1993 | Surg. Today | pmid:7686416 |
| Ueno M et al. | [Immunosuppressive effect in combination therapy of cyclosporine A, FK506 and 15-deoxyspergualin on a pancreatic islet xenotransplantation]. | 1993 | Nihon Geka Gakkai Zasshi | pmid:7686615 |
| Thomson AW et al. | FK 506: a novel immunosuppressant for treatment of autoimmune disease. Rationale and preliminary clinical experience at the University of Pittsburgh. | 1993 | Springer Semin. Immunopathol. | pmid:7686690 |
| Koga T et al. | Pulmonary infiltrates recovered by FK506 in a patient with Behçet's disease. | 1993 | Chest | pmid:7686837 |
| Valdivia LA et al. | Dendritic cell replacement in long-surviving liver and cardiac xenografts. | 1993 | Transplantation | pmid:7689265 |
| Odocha O et al. | Posttransplant diabetes mellitus in African Americans after renal transplantation under FK 506 immunosuppression. | 1993 | Transplant. Proc. | pmid:7689268 |
| Odocha O et al. | Serum cholesterol levels in African Americans after renal transplantation under FK 506 immunosuppression. | 1993 | Transplant. Proc. | pmid:7689269 |
| McCauley J et al. | Renal transplantation under FK 506 in African-Americans: early experience. | 1993 | Transplant. Proc. | pmid:7689270 |
| Groth CG et al. | New immunosuppressive drugs in transplantation. | 1993 | Transplant. Proc. | pmid:7689274 |
| Olivera DL et al. | Divergent effects of rapamycin on mouse and rat cells following mitogenic stimulation. | 1993 | Clin. Immunol. Immunopathol. | pmid:7690317 |
| Whitington PF et al. | Orthotopic auxiliary liver transplantation for Crigler-Najjar syndrome type 1. | 1993 | Lancet | pmid:7690444 |
| Takahashi H and Iizuka H | Neither cyclosporin A nor FK506 affects adenylate cyclase responses of fetal rat keratinizing epidermal cells (FRSK cells) at concentrations that inhibit thymidine incorporation. | 1993 | J. Dermatol. Sci. | pmid:7511000 |