| MeSH term | MeSH ID | Detail |
|---|---|---|
| Orchitis | D009920 | 1 associated lipids |
| Phyllodes Tumor | D003557 | 1 associated lipids |
| Meningitis, Fungal | D016921 | 1 associated lipids |
| Malocclusion, Angle Class II | D008312 | 1 associated lipids |
| Flaviviridae Infections | D018178 | 1 associated lipids |
| Idiopathic Interstitial Pneumonias | D054988 | 1 associated lipids |
| Dysuria | D053159 | 1 associated lipids |
| Denys-Drash Syndrome | D030321 | 1 associated lipids |
| Akinetic Mutism | D000405 | 1 associated lipids |
| Sleep Apnea, Central | D020182 | 1 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Caraveo G et al. | FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29229832 |
| Varshosaz J et al. | Physicochemical, Pharmacodynamic and Pharmacokinetic Characterization of Soluplus Stabilized Nanosuspension of Tacrolimus. | 2017 | Curr Drug Deliv | pmid:27697037 |
| Liu C et al. | Tacrolimus Improves Symptoms of Children With Myasthenia Gravis Refractory to Prednisone. | 2017 | Pediatr. Neurol. | pmid:29074055 |
| Cheung AY et al. | Probable Donor-Derived Cytomegalovirus Disease After Keratolimbal Allograft Transplantation. | 2017 | Cornea | pmid:28614157 |
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| Weir MR et al. | Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial. | 2017 | Transplantation | pmid:26950714 |
| Jouve T et al. | New formulations of tacrolimus and prevention of acute and chronic rejections in adult kidney-transplant recipients. | 2017 | Expert Opin Drug Saf | pmid:28494654 |
| Koo K et al. | Beyond monotherapy: a systematic review on creative strategies in topical therapy of psoriasis. | 2017 | J Dermatolog Treat | pmid:28481664 |
| Wolfshohl JA et al. | Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment. | 2017 | Lasers Surg Med | pmid:27552666 |
| Heemann U and Viklicky O | Is trough level variability the new tool for identifying patients at risk for rejection after transplantation? | 2017 | Nephrol. Dial. Transplant. | pmid:28186537 |
| Gardenier JC et al. | Topical tacrolimus for the treatment of secondary lymphedema. | 2017 | Nat Commun | pmid:28186091 |
| Verga E et al. | Stoma Complications: Corticosteroid and Silver Nitrate-Resistant Inflammation Successfully Treated with Topical Tacrolimus. | 2017 | Dig Surg | pmid:28183090 |
| Størset E et al. | Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. | 2017 | Br J Clin Pharmacol | pmid:28374426 |
| Kizilbash SJ et al. | Infection rates in tacrolimus versus cyclosporine-treated pediatric kidney transplant recipients on a rapid discontinuation of prednisone protocol: 1-year analysis. | 2017 | Pediatr Transplant | pmid:28371243 |
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| Ikeda K et al. | Intestinal perforation due to hemorrhagic Cytomegalovirus enteritis in a patient with severe uncontrolled lupus nephritis: a case and review of the literature. | 2017 | Rheumatol. Int. | pmid:28283734 |
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| Ma TK et al. | Therapeutic drug monitoring of once-daily tacrolimus (Advagraf) in a gastrectomized kidney transplant recipient. | 2017 | Nephrology (Carlton) | pmid:28064453 |
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| Obaidat RM et al. | Using Supercritical Fluid Technology (SFT) in Preparation of Tacrolimus Solid Dispersions. | 2017 | AAPS PharmSciTech | pmid:27116202 |
| Krämer BK et al. | Efficacy of Prolonged- and Immediate-release Tacrolimus in Kidney Transplantation: A Pooled Analysis of Two Large, Randomized, Controlled Trials. | 2017 | Transplant. Proc. | pmid:29149958 |
| de Menezes AF et al. | Pharmacologic Treatment of Vitiligo in Children and Adolescents: A Systematic Review. | 2017 | Pediatr Dermatol | pmid:27878842 |
| Taber DJ et al. | A Comparative Effectiveness Analysis of Early Steroid Withdrawal in Black Kidney Transplant Recipients. | 2017 | Clin J Am Soc Nephrol | pmid:27979979 |
| Flahault A et al. | Clinical impact of the CYP3A5 6986A>G allelic variant on kidney transplantation outcomes. | 2017 | Pharmacogenomics | pmid:27977332 |
| Tron C et al. | Tacrolimus: Does direct glucuronidation matter? An analytical and pharmacological perspective. | 2017 | Pharmacol. Res. | pmid:28366836 |
| Ganschow R et al. | Everolimus and reduced calcineurin inhibitor therapy in pediatric liver transplant recipients: Results from a multicenter, prospective study. | 2017 | Pediatr Transplant | pmid:28714558 |
| Bremer S et al. | NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation. | 2017 | Br J Clin Pharmacol | pmid:28686294 |
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| Olariu R et al. | Intra-graft injection of tacrolimus promotes survival of vascularized composite allotransplantation. | 2017 | J. Surg. Res. | pmid:28985877 |
| Tao X et al. | Long-term efficacy and side effects of low-dose tacrolimus for the treatment of Myasthenia Gravis. | 2017 | Neurol. Sci. | pmid:27873026 |
| Mehta RS et al. | Post-transplantation cyclophosphamide versus conventional graft-versus-host disease prophylaxis in mismatched unrelated donor haematopoietic cell transplantation. | 2016 | Br. J. Haematol. | pmid:26947769 |
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| Kolb M et al. | Risk Factors for Subtherapeutic Tacrolimus Levels after Conversion from Continuous Intravenous Infusion to Oral in Children after Allogeneic Hematopoietic Cell Transplantation. | 2016 | Biol. Blood Marrow Transplant. | pmid:26880117 |
| Arreola-Guerra JM et al. | Tacrolimus Trough Levels as a Risk Factor for Acute Rejection in Renal Transplant Patients. | 2016 | Ann. Transplant. | pmid:26879833 |
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| Dharnidharka VR et al. | Differential risks for adverse outcomes 3 years after kidney transplantation based on initial immunosuppression regimen: a national study. | 2016 | Transpl. Int. | pmid:27564782 |
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| Guo YW et al. | Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients. | 2016 | World J. Gastroenterol. | pmid:27350740 |
| Yingfang F et al. | Pimecrolimus micelle exhibits excellent therapeutic effect for Keratoconjunctivitis Sicca. | 2016 | Colloids Surf B Biointerfaces | pmid:26731192 |
| Nekkanti V et al. | Design, Characterization, and In Vivo Pharmacokinetics of Tacrolimus Proliposomes. | 2016 | AAPS PharmSciTech | pmid:26729532 |
| Armand P et al. | The addition of sirolimus to the graft-versus-host disease prophylaxis regimen in reduced intensity allogeneic stem cell transplantation for lymphoma: a multicentre randomized trial. | 2016 | Br. J. Haematol. | pmid:26729448 |
| Choi WJ et al. | Oral administration of Lactococcus chungangensis inhibits 2,4-dinitrochlorobenzene-induced atopic-like dermatitis in NC/Nga mice. | 2016 | J. Dairy Sci. | pmid:27289147 |
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| Fang YP et al. | What is the discrepancy between drug permeation into/across intact and diseased skins? Atopic dermatitis as a model. | 2016 | Int J Pharm | pmid:26657274 |
| Thao le Q et al. | Pharmaceutical potential of tacrolimus-loaded albumin nanoparticles having targetability to rheumatoid arthritis tissues. | 2016 | Int J Pharm | pmid:26657273 |
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| Albeiroti S et al. | Evaluation of 2 Batched Pretreatment Systems for the Measurement of Whole Blood Tacrolimus on the ARCHITECT Immunoassay Analyzer. | 2016 | Lab Med | pmid:27474776 |
| Yu H et al. | Risk factors for new-onset diabetes mellitus after living donor kidney transplantation in Korea - a retrospective single center study. | 2016 | BMC Nephrol | pmid:27473469 |
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| Constantinescu AA et al. | Differential influence of tacrolimus and sirolimus on mitochondrial-dependent signaling for apoptosis in pancreatic cells. | 2016 | Mol. Cell. Biochem. | pmid:27344165 |
| Shao K et al. | Different Effects of Tacrolimus on Innate and Adaptive Immune Cells in the Allograft Transplantation. | 2016 | Scand. J. Immunol. | pmid:26524694 |
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| Pizzo HP et al. | Sirolimus and tacrolimus coefficient of variation is associated with rejection, donor-specific antibodies, and nonadherence. | 2016 | Pediatr. Nephrol. | pmid:27286686 |
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| Youssef M et al. | Asymptomatic papulonodular lesions in zosteriform distribution in an immunocompromised patient. | 2016 | Int. J. Dermatol. | pmid:26463835 |
| Ferjani H et al. | The evaluate and compare the effects of the Tacrolimus and Sirolimus on the intestinal system using an intestinal cell culture model. | 2016 | Toxicol. Mech. Methods | pmid:26460985 |
| Sasaki T et al. | Characteristic features of tacrolimus-induced lung disease in rheumatoid arthritis patients. | 2016 | Clin. Rheumatol. | pmid:25644583 |
| Serrano-Mollar A et al. | Safety and Tolerability of Alveolar Type II Cell Transplantation in Idiopathic Pulmonary Fibrosis. | 2016 | Chest | pmid:27020420 |
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| Seok J et al. | Recalcitrant steroid-induced rosacea successfully treated with 0.03% tacrolimus and 595-nm pulsed dye laser. | 2016 | Eur J Dermatol | pmid:27193042 |
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| Alvarez-ElÃas AC et al. | CYP3A5 Genotype and Time to Reach Tacrolimus Therapeutic Levels in Renal Transplant Children. | 2016 | Transplant. Proc. | pmid:27110018 |
| Reiner J et al. | After Intestinal Transplantation Kidney Function Is Impaired by Downregulation of Epithelial Ion Transporters in the Ileum. | 2016 | Transplant. Proc. | pmid:27109987 |
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| Chang HK et al. | Ten-Year Experience With Bowel Transplantation at Seoul St. Mary's Hospital. | 2016 | Transplant. Proc. | pmid:27109981 |
| Felix MJ et al. | Time-Dependent and Immunosuppressive Drug-Associated Adverse Event Profiles in De Novo Kidney Transplant Recipients Converted from Tacrolimus to Sirolimus Regimens. | 2016 | Pharmacotherapy | pmid:26799522 |
| Adler M et al. | A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro. | 2016 | J. Am. Soc. Nephrol. | pmid:26260164 |
| Kishida N et al. | Increased Incidence of Thrombotic Microangiopathy After ABO-Incompatible Living Donor Liver Transplantation. | 2016 | Ann. Transplant. | pmid:27956735 |
| Wang Y et al. | Preparation, characterization and in vivo evaluation of amorphous tacrolimus nanosuspensions produced using CO2-assisted in situ nanoamorphization method. | 2016 | Int J Pharm | pmid:27034003 |
| Jimbo H et al. | Telangiectatic lichen sclerosus on the cheek successfully treated with topical tacrolimus. | 2016 | Eur J Dermatol | pmid:27033557 |
| Shimizu K et al. | Specific delivery of an immunosuppressive drug to splenic B cells by antigen-modified liposomes and its antiallergic effect. | 2016 | J Drug Target | pmid:27030163 |
| Yan Y et al. | Robust Axonal Regeneration in a Mouse Vascularized Composite Allotransplant Model Undergoing Delayed Tissue Rejection. | 2016 | Hand (N Y) | pmid:28149214 |
| Ha DH et al. | Potential differentiation ability of gingiva originated human mesenchymal stem cell in the presence of tacrolimus. | 2016 | Sci Rep | pmid:27721434 |
| Carrillo-Ibarra S et al. | The Oxidative and Inflammatory State in Patients with Acute Renal Graft Dysfunction Treated with Tacrolimus. | 2016 | Oxid Med Cell Longev | pmid:27872679 |
| Thomusch O et al. | Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial. | 2016 | Lancet | pmid:27871759 |