tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Biliary Tract Neoplasms D001661 7 associated lipids
Blepharitis D001762 4 associated lipids
Blindness D001766 6 associated lipids
Body Weight D001835 333 associated lipids
Bone Diseases D001847 4 associated lipids
Bradycardia D001919 13 associated lipids
Brain Diseases D001927 27 associated lipids
Brain Edema D001929 20 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Shin TH et al. Formulation and in vivo pharmacokinetic evaluation of ethyl cellulose-coated sustained release multiple-unit system of tacrolimus. 2018 Int. J. Biol. Macromol. pmid:29277422
Moriguchi S et al. Reduced expression of Na/Ca exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice. 2018 Neuropharmacology pmid:29274751
Karagun BS et al. Eye Movement Disorders Following Allogeneic Bone Marrow Transplantation on FK506 (Tacrolimus) and Ganciclovir. 2018 J. Pediatr. Hematol. Oncol. pmid:28731920
Komura Y et al. Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data. 2018 J. Dermatol. pmid:29168213
Cho EJ et al. Performance of the Dimension TAC assay and comparison of multiple platforms for the measurement of tacrolimus. 2018 J. Clin. Lab. Anal. pmid:29148096
Akamine Y et al. A comparison of the effects of CYP3A5 polymorphism on tacrolimus blood concentrations measured by 4 immunoassay methods in renal transplant patients. 2018 J Clin Pharm Ther pmid:28891077
Pflugrad H et al. Longterm calcineurin inhibitor therapy and brain function in patients after liver transplantation. 2018 Liver Transpl. pmid:29156491
Liu YJ et al. Pooled analysis of the comparative efficacy between tacrolimus and infliximab for ulcerative colitis. 2018 Medicine (Baltimore) pmid:30095612
Garaix F et al. Tacrolimus Granules for Oral Suspension as Post-Transplant Immunosuppression in Routine Medical Practice in France: The OPTIMOD Study. 2018 Ann. Transplant. pmid:30093607
Wang DD et al. Population pharmacokinetics of tacrolimus in paediatric systemic lupus erythematosus based on real-world study. 2018 J Clin Pharm Ther pmid:29766530
Rigo-Bonnin R et al. Different top-down approaches to estimate measurement uncertainty of whole blood tacrolimus mass concentration values. 2018 Clin. Biochem. pmid:29750938
Strohbehn GW et al. Large-Scale Variability of Inpatient Tacrolimus Therapeutic Drug Monitoring at an Academic Transplant Center: A Retrospective Study. 2018 Ther Drug Monit pmid:29750738
Nakagita K et al. Effect of fluconazole on the pharmacokinetics of everolimus and tacrolimus in a heart transplant recipient: Case report. 2018 Int J Clin Pharmacol Ther pmid:29648533
Kaya Z et al. Tacrolimus-Induced Autoimmune Hemolytic Anemia in a Previously Reported Child With History of Thrombocytopenia Following Liver Transplant. 2018 Exp Clin Transplant pmid:29633932
Nanmoku K et al. Steroid Withdrawal Using Everolimus in ABO-Incompatible Kidney Transplant Recipients With Post-Transplant Diabetes Mellitus. 2018 Transplant. Proc. pmid:29631750
Takeuchi K et al. Comparison of Safety and Efficacy of Tacrolimus versus Infliximab for Active Ulcerative Colitis. 2018 Dig Dis pmid:29050007
Mashiah J et al. Topical pimecrolimus for paediatric cutaneous mastocytosis. 2018 Clin. Exp. Dermatol. pmid:29460435
Chen ZH et al. Adenovirus-mediated OX40Ig gene transfer induces long-term survival of orthotopic liver allograft in rats. 2018 Transpl. Immunol. pmid:29454984
Yang MY et al. High rates of secondary non-adherence causes decreased efficacy of 0.1% topical tacrolimus in adult eczema patients: results from a multicenter clinical trial. 2018 J Dermatolog Treat pmid:28670943
Dheer D et al. Tacrolimus: An updated review on delivering strategies for multifarious diseases. 2018 Eur J Pharm Sci pmid:29277665