Tzakis AG et al. |
Two-year experience with FK 506 in pediatric patients. |
1993 |
Transplant. Proc. |
pmid:7679822
|
Gibbs JF et al. |
Outcome analysis of FK 506 therapy for acute and chronic rejection. |
1993 |
Transplant. Proc. |
pmid:7679823
|
|
Morphological characteristics of renal allografts showing renal dysfunction under FK 506 therapy: is graft biopsy available to reveal the morphological findings corresponding with FK 506 nephropathy? Japanese FK 506 Study Group. |
1993 |
Transplant. Proc. |
pmid:7679824
|
Alessiani M et al. |
Adverse effects of FK 506 overdosage after liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7679825
|
Klintmalm GB et al. |
Use of FK 506 for the prevention of recurrent allograft rejection after successful conversion from cyclosporine for refractory rejection. US Multicenter FK 506 Liver Study Group. |
1993 |
Transplant. Proc. |
pmid:7679826
|
Jordan ML et al. |
FK 506 salvage of renal allografts with ongoing rejection failing cyclosporine immunosuppression. |
1993 |
Transplant. Proc. |
pmid:7679827
|
Klintmalm GB et al. |
Prognostic factors for successful conversion from cyclosporine to FK 506-based immunosuppressive therapy for refractory rejection after liver transplantation. US Multicenter FK 506 Liver Study Group. |
1993 |
Transplant. Proc. |
pmid:7679828
|
Lane BC et al. |
Evaluation of calcineurin's role in the immunosuppressive activity of FK 506, related macrolactams, and cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7679829
|
Celli S et al. |
Long-term survival of heart and liver xenografts with splenectomy and FK 506. |
1993 |
Transplant. Proc. |
pmid:7679830
|
Woan MC et al. |
Characterization of the biopsy growth assay in monitoring cardiac transplant patients for rejection. |
1993 |
Transplant. Proc. |
pmid:7680171
|
Rilo HR et al. |
Effect of intraportal human islet transplantation on kidney graft survival in simultaneous kidney-islet allografts. |
1993 |
Transplant. Proc. |
pmid:7680172
|
Fukuzaki T et al. |
Induction of unresponsiveness to islet allograft by preoperative donor spleen cell injection and FK 506 treatment. |
1993 |
Transplant. Proc. |
pmid:7680173
|
Schweizer M et al. |
Sensitivity of mitochondrial peptidyl-prolyl cis-trans isomerase, pyridine nucleotide hydrolysis and Ca2+ release to cyclosporine A and related compounds. |
1993 |
Biochem. Pharmacol. |
pmid:7680201
|
Hirao A et al. |
Effects of immunosuppressants, FK506, deoxyspergualin, and cyclosporine A on immature human hematopoiesis. |
1993 |
Blood |
pmid:7680241
|
Tamura K et al. |
Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production. |
1993 |
Clin. Exp. Immunol. |
pmid:7680293
|
Armitage JM et al. |
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7680396
|
Randhawa PS et al. |
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine. |
1993 |
Am. J. Surg. Pathol. |
pmid:7680544
|
Xu RX et al. |
Heteronuclear 3D NMR studies of water bound to an FK506 binding protein/immunosuppressant complex. |
1993 |
Biochemistry |
pmid:7680570
|
Jayaraman T and Marks AR |
Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line. |
1993 |
J. Biol. Chem. |
pmid:7503980
|
D'Ambrosio R et al. |
Validation and quality assurance program for monitoring tacrolimus (FK 506) concentrations in plasma and whole blood. |
1993 |
Ther Drug Monit |
pmid:7504339
|
Reese JC et al. |
The effect of FK506 on canine bile flow. |
1993 |
Transplantation |
pmid:7504342
|
Woodle ES et al. |
FK506--reversal of humorally mediated cardiac allograft rejection in the presence of preformed anti-class I antibody. |
1993 |
Transplantation |
pmid:7504346
|
Jindal RM et al. |
Effect of deoxyspergualin on the endocrine function of the rat pancreas. |
1993 |
Transplantation |
pmid:7504347
|
Kodama M et al. |
FK506 therapy of experimental autoimmune myocarditis after onset of the disease. |
1993 |
Am. Heart J. |
pmid:7504393
|
Woodle ES et al. |
FK 506 rescue therapy: early conversion improves efficacy. |
1993 |
Transplant. Proc. |
pmid:7682359
|
Woodle ES et al. |
FK 506 rescue therapy: the rapidity of rejection reversal is related to the subsequent development of CMV disease. |
1993 |
Transplant. Proc. |
pmid:7682360
|
Meiser BM et al. |
Simvastatin decreases accelerated graft vessel disease after heart transplantation in an animal model. |
1993 |
Transplant. Proc. |
pmid:7682363
|
Yu Y et al. |
Mutagenicity of the new immunosuppressive drugs, FK 506, and spergualin. |
1993 |
Transplant. Proc. |
pmid:7682364
|
Rao PN et al. |
Prediction of early graft function by effluent levels of hyaluronic acid in clinical liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7682366
|
Hutchison KA et al. |
FK506 binding to the 56-kilodalton immunophilin (Hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function. |
1993 |
Biochemistry |
pmid:7682438
|
Shorrock C and Neuberger J |
The changing face of liver transplantation. |
1993 |
Gut |
pmid:7682532
|
Nakajima J |
[The immunosuppressive effects of FK506 on single lung allotransplantation in Japanese monkey (Macaca fuscata)]. |
1993 |
Nihon Kyobu Geka Gakkai Zasshi |
pmid:7690829
|
Wenzel-Seifert K and Seifert R |
Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. |
1993 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:7690907
|
Yoshizawa K et al. |
Establishment of Epstein-Barr virus-associated lymphoma cell line SUBL with t(2;3)(p11;q27) from a liver transplant patient. |
1993 |
Cancer Genet. Cytogenet. |
pmid:7506636
|
Peters DH et al. |
Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. |
1993 |
Drugs |
pmid:7506654
|
Mühl H et al. |
Cyclosporin derivatives inhibit interleukin 1 beta induction of nitric oxide synthase in renal mesangial cells. |
1993 |
Eur. J. Pharmacol. |
pmid:7506668
|
Simek SL et al. |
Sequence and localization of a novel FK506-binding protein to mouse chromosome 11. |
1993 |
Genomics |
pmid:7507077
|
Quesniaux VF |
Immunosuppressants: tools to investigate the physiological role of cytokines. |
1993 |
Bioessays |
pmid:7507316
|
Shafiee A et al. |
Enzymatic synthesis and immunosuppressive activity of novel desmethylated immunomycins (ascomycins). |
1993 |
J. Antibiot. |
pmid:7693638
|
Keicho N et al. |
Antilymphocytic activity of erythromycin distinct from that of FK506 or cyclosporin A. |
1993 |
J. Antibiot. |
pmid:7693639
|
Timerman AP et al. |
The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Dissociation and reconstitution of FKBP-12 to the calcium release channel of skeletal muscle sarcoplasmic reticulum. |
1993 |
J. Biol. Chem. |
pmid:7693682
|
Schwaninger M et al. |
Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization. |
1993 |
J. Biol. Chem. |
pmid:7693684
|
Smith DF et al. |
FKBP54, a novel FK506-binding protein in avian progesterone receptor complexes and HeLa extracts. |
1993 |
J. Biol. Chem. |
pmid:7693698
|
Thomson AW et al. |
Comparative effects of rapamycin, FK 506 and cyclosporine on antibody production, lymphocyte populations and immunoglobulin isotype switching in the rat. |
1993 |
Immunopharmacol Immunotoxicol |
pmid:7693791
|
Tzakis AG et al. |
Intestinal transplantation in children under FK 506 immunosuppression. |
1993 |
J. Pediatr. Surg. |
pmid:7693907
|
Kawauchi M et al. |
Prolonged survival of orthotopically transplanted heart xenograft in infant baboons. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7693999
|
Shutter LA et al. |
Cortical blindness and white matter lesions in a patient receiving FK506 after liver transplantation. |
1993 |
Neurology |
pmid:7694189
|
Sato M et al. |
FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. |
1993 |
Acta Endocrinol. |
pmid:7509103
|
Clipstone NA and Crabtree GR |
Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509131
|
Takahara S |
Efficacy of FK506 in renal transplantation. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509132
|
Thomson AW et al. |
Incidence of CD4+ IL-2R alpha+ and CD4+ CD45RA+ T-cells in progressive multiple sclerosis and the influence of short-term (3 months) FK 506 therapy. |
1993 |
Ann. N. Y. Acad. Sci. |
pmid:7509133
|
Wallemacq PE et al. |
Improvement and assessment of enzyme-linked immunosorbent assay to detect low FK506 concentrations in plasma or whole blood within 6 hours. |
1993 |
Clin. Chem. |
pmid:7684956
|
Mochizuki M et al. |
A clinical trial of FK506 in refractory uveitis. |
1993 |
Am. J. Ophthalmol. |
pmid:7685147
|
Ocain TD et al. |
A nonimmunosuppressive triene-modified rapamycin analog is a potent inhibitor of peptidyl prolyl cis-trans isomerase. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7685167
|
Asami M et al. |
Detection of the FK506-FKBP-calcineurin complex by a simple binding assay. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7685169
|
Metcalfe S et al. |
Prodigiosin 25C: effect in in vitro models for T cell activation and T cell cycling and in vivo for rat heart allografts. |
1993 |
Int. Arch. Allergy Immunol. |
pmid:7685216
|
Bumgardner GL and Roberts JP |
New immunosuppressive agents. |
1993 |
Gastroenterol. Clin. North Am. |
pmid:7685324
|
Ahmed SS et al. |
Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. |
1993 |
J. Pharmacol. Exp. Ther. |
pmid:7685382
|
Sewell KL |
Immunotherapy and other novel therapies, including biologic response modifiers, apheresis, and dietary modifications. |
1993 |
Curr Opin Rheumatol |
pmid:7685614
|
Warty V et al. |
FK506 measurement: comparison of different analytical methods. |
1993 |
Ther Drug Monit |
pmid:7687389
|
Iwata H et al. |
Suppression of allograft responses by combining donor alloantigen-specific intravenous presensitization with suboptimal doses of FK506. |
1993 |
Transplantation |
pmid:7687396
|
Roelen DL et al. |
Differential inhibition of primed alloreactive CTLs in vitro by clinically used concentrations of cyclosporine and FK506. |
1993 |
Transplantation |
pmid:7687397
|
Antoni FA et al. |
Inhibitory role for calcineurin in stimulus-secretion coupling revealed by FK506 and cyclosporin A in pituitary corticotrope tumor cells. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7687429
|
Denesyuk AI et al. |
Comparison of conformations of cyclosporin A and macrolide FK506 fragments: localization of putative binding sites with phosphatase calcineurin. |
1993 |
Biochem. Biophys. Res. Commun. |
pmid:7687433
|
Altmeyer A and Dumont FJ |
Rapamycin inhibits IL-1-mediated interferon-gamma production in the YAC-1 T cell lymphoma. |
1993 |
Cytokine |
pmid:7687472
|
Przepiorka D et al. |
Bronchiolitis obliterans organizing pneumonia in a BMT patient receiving FK506. |
1993 |
Bone Marrow Transplant. |
pmid:7687503
|
Bram RJ et al. |
Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location. |
1993 |
Mol. Cell. Biol. |
pmid:7687744
|
Heitman J et al. |
The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. |
1993 |
Mol. Cell. Biol. |
pmid:7687745
|
Winkler M et al. |
Plasma level-guided low-dose FK 506 therapy in patients with early liver dysfunction after liver transplantation. |
1993 |
Transplant. Proc. |
pmid:7689277
|
Viebahn R et al. |
Simulation of hypoxic and preservation injury in human hepatocyte cultures: influence of FK 506 and cyclosporine. |
1993 |
Transplant. Proc. |
pmid:7689278
|
Dé P et al. |
Early steroid-resistant rejection following orthotopic liver transplantation: new aspects of treatment with FK 506 instead of OKT3? |
1993 |
Transplant. Proc. |
pmid:7689279
|
Ueda D et al. |
Influence of FK 506 on renal blood flow. |
1993 |
Transplant. Proc. |
pmid:7689280
|
Ohzato H et al. |
Serum interleukin-6 levels as an indicator of acute rejection after liver transplantation in cynomologous monkeys. |
1993 |
Surg. Today |
pmid:7689373
|
Fesik SW |
NMR structure-based drug design. |
1993 |
J. Biomol. NMR |
pmid:7689377
|
McManus BM et al. |
Direct myocardial injury by enterovirus: a central role in the evolution of murine myocarditis. |
1993 |
Clin. Immunol. Immunopathol. |
pmid:7689428
|
Namiki Y et al. |
Tautomeric phenomenon of a novel potent immunosuppressant (FK506) in solution. I. Isolation and structure determination of tautomeric compounds. |
1993 |
J. Antibiot. |
pmid:7689551
|
Kondo T et al. |
[Antitumor sensitivity test, subrenal capsule assay using FK-506: preliminary report]. |
1993 |
Nihon Geka Gakkai Zasshi |
pmid:7689693
|
Lee KK et al. |
Successful treatment of ongoing intestinal allograft rejection permits recovery of graft structure and function. |
1993 |
Am. J. Surg. |
pmid:7678188
|
Galvin F et al. |
Effects of cyclosporin A, FK 506, and mycalamide A on the activation of murine CD4+ T cells by the murine B7 antigen. |
1993 |
Eur. J. Immunol. |
pmid:7678228
|
Foxwell BM et al. |
Inhibition of activation-induced changes in the structure of the T cell interleukin-7 receptor by cyclosporin A and FK506. |
1993 |
Eur. J. Immunol. |
pmid:7678231
|
Hirai T et al. |
Prolonged lung allograft survival with a short course of FK 506. |
1993 |
J. Thorac. Cardiovasc. Surg. |
pmid:7678313
|
Ibarra F et al. |
Bidirectional regulation of Na+,K(+)-ATPase activity by dopamine and an alpha-adrenergic agonist. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:7678337
|
Murase N et al. |
Graft-versus-host disease after brown Norway-to-Lewis and Lewis-to-Brown Norway rat intestinal transplantation under FK506. |
1993 |
Transplantation |
pmid:7678353
|
Herold KC et al. |
Inhibition of glucose-stimulated insulin release from beta TC3 cells and rodent islets by an analog of FK506. |
1993 |
Transplantation |
pmid:7678356
|
Holman MJ et al. |
FK506-associated thrombotic thrombocytopenic purpura. |
1993 |
Transplantation |
pmid:7678357
|
Griffiths EJ and Halestrap AP |
Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts. |
1993 |
J. Mol. Cell. Cardiol. |
pmid:7512654
|
Piekoszewski W et al. |
Disposition of tacrolimus (FK 506) in rabbits. Role of red blood cell binding in hepatic clearance. |
1993 Jul-Aug |
Drug Metab. Dispos. |
pmid:7690698
|
Kobayashi J et al. |
A new rat infection-heart transplant model: effect of infection on graft survival studies. |
1993 Jul-Aug |
J. Heart Lung Transplant. |
pmid:7690253
|
Schreier MH |
Immunophilins and immunosuppression. |
1993 Mar-Apr |
Clin. Exp. Rheumatol. |
pmid:7686830
|
Iwasaki K et al. |
Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone. |
1993 Nov-Dec |
Drug Metab. Dispos. |
pmid:7507815
|
Fukuse T et al. |
Combined therapy with FK-506 and cyclosporine for canine lung allotransplantation: immunosuppressive effects and blood trough levels. |
1993 Nov-Dec |
J. Heart Lung Transplant. |
pmid:7508750
|
Morris RE |
New small molecule immunosuppressants for transplantation: review of essential concepts. |
1993 Nov-Dec |
J. Heart Lung Transplant. |
pmid:7508752
|
Lhoëst G et al. |
Isolation and identification of a novel isomerized epoxide metabolite of FK-506 from erythromycin-induced rabbit liver microsomes. |
1993 Sep-Oct |
Drug Metab. Dispos. |
pmid:7694828
|
Fruman DA et al. |
Immunophilins in protein folding and immunosuppression. |
1994 |
FASEB J. |
pmid:7513288
|
Nishimori H et al. |
Combination therapy with FK 506 and splenectomy may induce tolerance in cardiac xenografts. |
1994 |
Transplant. Proc. |
pmid:7518102
|
Helekar SA et al. |
Prolyl isomerase requirement for the expression of functional homo-oligomeric ligand-gated ion channels. |
1994 |
Neuron |
pmid:7507339
|
Parsons JN et al. |
Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex. |
1994 |
J. Biol. Chem. |
pmid:7518461
|
Nakata S et al. |
Immunosuppressive mechanisms of deoxymethylspergualin and FK 506 on in vitro cytotoxic T lymphocytes. |
1994 |
Transplant. Proc. |
pmid:7520613
|
Tamir H et al. |
Secretogogue-induced gating of chloride channels in the secretory vesicles of parafollicular cells. |
1994 |
Endocrinology |
pmid:7525261
|
Lea JP et al. |
Evidence that the inhibition of Na+/K(+)-ATPase activity by FK506 involves calcineurin. |
1994 |
Kidney Int. |
pmid:7527873
|