tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Papillomavirus Infections D030361 4 associated lipids
Denys-Drash Syndrome D030321 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Polyomavirus Infections D027601 1 associated lipids
Coronary Stenosis D023921 6 associated lipids
Lacerations D022125 1 associated lipids
Brachial Plexus Neuritis D020968 2 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Central Nervous System Viral Diseases D020805 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Vandenbussche C et al. Tacrolimus-induced nephrotoxicity in mice is associated with microRNA deregulation. 2018 Arch. Toxicol. pmid:29362864
Youssef A et al. Angiolymphoid hyperplasia with eosinophilia: a case report. 2018 J Med Case Rep pmid:29606120
Huh KH et al. De novo low-dose sirolimus versus mycophenolate mofetil in combination with extended-release tacrolimus in kidney transplant recipients: a multicentre, open-label, randomized, controlled, non-inferiority trial. 2017 Nephrol. Dial. Transplant. pmid:28810721
Lloberas N et al. The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation. 2017 Pharmacogenet. Genomics pmid:28704257
Gooptu M and Koreth J Better acute graft--host disease outcomes for allogeneic transplant recipients in the modern era: a tacrolimus effect? 2017 Haematologica pmid:28458253
Costa JS et al. Polyomavirus Nephropathy: Ten-Year Experience. 2017 Transplant. Proc. pmid:28457399
Chiasson VL et al. Regulatory T-Cell Augmentation or Interleukin-17 Inhibition Prevents Calcineurin Inhibitor-Induced Hypertension in Mice. 2017 Hypertension pmid:28584011
Shoda W et al. Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake. 2017 Kidney Int. pmid:28341239
Zhang X et al. Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients. 2017 Dis. Markers pmid:28246425
Juvvadi PR et al. Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. 2017 Virulence pmid:27325145
D'Avola D et al. Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. 2017 Liver Transpl. pmid:28160394
Andreu F et al. A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach. 2017 Clin Pharmacokinet pmid:28050888
Shimizu K Development of New Liposome Targeting Strategies for Application of Disease Therapies. 2017 Yakugaku Zasshi pmid:28049894
Maneechote C et al. Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury. 2017 J. Cell. Mol. Med. pmid:28941171
Shrestha BM Two Decades of Tacrolimus in Renal Transplant: Basic Science and Clinical Evidences. 2017 Exp Clin Transplant pmid:27938316
Yu MY et al. Short-term anti-proteinuric effect of tacrolimus is not related to preservation of the glomerular filtration rate in IgA nephropathy: A 5-year follow-up study. 2017 PLoS ONE pmid:29155873
Gonzalez-Andrades M et al. Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option. 2017 Eye Contact Lens pmid:26222098
Olmedo Martín RV et al. Medium to long-term efficacy and safety of oral tacrolimus in moderate to severe steroid refractory ulcerative colitis. 2017 Rev Esp Enferm Dig pmid:28617029
Maldonado AQ et al. Prevalence of CYP3A5 Genomic Variances and Their Impact on Tacrolimus Dosing Requirements among Kidney Transplant Recipients in Eastern North Carolina. 2017 Pharmacotherapy pmid:28605053
Pietrosi G and Chinnici C Report on Liver Cell Transplantation Using Human Fetal Liver Cells. 2017 Methods Mol. Biol. pmid:27830561