tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Persić-Vojinović S et al. | Disseminated Hailey-Hailey disease treated with topical tacrolimus and oral erythromycin: Case report and review of the literature. | 2006 | Acta Dermatovenerol Croat | pmid:17311740 |
| Louvain D et al. | Lichen sclerosus in the oral mucosa: a rare form of presentation. | 2012 | Acta Dermatovenerol Croat | pmid:22507475 |
| Lipozencić J | Pimecrolimus--a safe and effective local immunomodulator in the treatment of inflammatory skin diseases. | 2005 | Acta Dermatovenerol Croat | pmid:15788149 |
| Pustisek N et al. | Tacrolimus ointment: a new therapy for atopic dermatitis--review of the literature. | 2002 | Acta Dermatovenerol Croat | pmid:12137728 |
| Polastri L et al. | Secretory defects induced by immunosuppressive agents on human pancreatic beta-cells. | 2002 | Acta Diabetol | pmid:12486498 |
| Sato M et al. | FK506 inhibits phytohemagglutinin-, but not interferon-gamma-, induced HLA-DR antigen expression and accessory cell function on primary cultured human thyroid cells. | 1993 | Acta Endocrinol. | pmid:7509103 |
| Pirenne J | Contribution of large animal models to the development of clinical intestinal transplantation. | 1999 Apr-Jun | Acta Gastroenterol. Belg. | pmid:10427786 |
| Jamieson NV | Adult small intestinal transplantation in Europe. | 1999 Apr-Jun | Acta Gastroenterol. Belg. | pmid:10427790 |
| Bonaccorsi-Riani E et al. | Impact of steroid-avoidance immunosuppression on long-term outcome after liver transplantation for HCV cirrhosis: the need for well documented long-term follow-up. | 2012 | Acta Gastroenterol. Belg. | pmid:23402084 |
| Reding R et al. | Stepwise minimization of the immunosuppressive therapy in pediatric liver transplantation. A conceptual approach towards operational tolerance. | 2005 Jul-Sep | Acta Gastroenterol. Belg. | pmid:16268418 |
| Varela E | [Small bowel transplantation]. | 1995 | Acta Gastroenterol. Latinoam. | pmid:7544939 |
| Okada M et al. | Successful treatment of chronic graft-versus-host disease with sulfasalazine in allogeneic bone marrow transplantation. | 1999 | Acta Haematol. | pmid:10529517 |
| Kraus TS et al. | Angioimmunoblastic T cell lymphoma: an unusual presentation of posttransplant lymphoproliferative disorder in a pediatric patient. | 2014 | Acta Haematol. | pmid:24157860 |
| Mesar I et al. | [Outcome of renal transplantation after tacrolimus switch to cyclosporine]. | 2011 | Acta Med Croatica | pmid:22359902 |
| Wardhana EA and Datau | A patient with plaque type morphea mimicking systemic lupus erythematosus. | 2015 | Acta Med Indones | pmid:26260557 |
| Kuinose M et al. | Calcineurin antagonists inhibit interferon-gamma production by downregulation of interleukin-18 in human mixed lymphocyte reactions. | 2000 | Acta Med. Okayama | pmid:11061569 |
| Takagi K et al. | Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation. | 2017 | Acta Med. Okayama | pmid:28238015 |
| Tanaka K et al. | Immunophilin ligands prevent H2O2-induced apoptotic cell death by increasing glutathione levels in neuro 2A neuroblastoma cells. | 2000 | Acta Med. Okayama | pmid:11132921 |
| Setkowicz Z and Guzik R | Injections of vehicle, but not cyclosporin A or tacrolimus (FK506), afford neuroprotection following injury in the developing rat brain. | 2007 | Acta Neurobiol Exp (Wars) | pmid:18320718 |
| Luchowska E et al. | FK506 attenuates 1-methyl-4-phenylpyridinium- and 3-nitropropionic acid-evoked inhibition of kynurenic acid synthesis in rat cortical slices. | 2003 | Acta Neurobiol Exp (Wars) | pmid:12926536 |