Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dell'Antonio G and Randhawa PS | "Striped" pattern of medullary ray fibrosis in allograft biopsies from kidney transplant recipients maintained on tacrolimus. | 1999 | Transplantation | pmid:10030300 |
Shapiro R et al. | A prospective, randomized trial of tacrolimus/prednisone versus tacrolimus/prednisone/mycophenolate mofetil in renal transplant recipients. | 1999 | Transplantation | pmid:10030287 |
McDiarmid SV et al. | Factors affecting growth after pediatric liver transplantation. | 1999 | Transplantation | pmid:10030286 |
Atta MG et al. | Tyrosine kinase inhibitors and immunosuppressants perturb the myo-inositol but not the betaine cotransporter in isotonic and hypertonic MDCK cells. | 1999 | Kidney Int. | pmid:10027932 |
Clemann N and Bechter R | Effects of rapamycin and FK 506 on rat Sertoli cells in vitro. | 1998 | Adv. Exp. Med. Biol. | pmid:10026935 |
Scholz C et al. | R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays. | 1999 | FEBS Lett. | pmid:10025965 |
Powers JF et al. | Discordant effects of rapamycin on proliferation and p70S6 kinase phosphorylation in normal and neoplastic rat chromaffin cells. | 1999 | Neurosci. Lett. | pmid:10025577 |
Reynolds PD et al. | Glucocorticoid resistance in the squirrel monkey is associated with overexpression of the immunophilin FKBP51. | 1999 | J. Clin. Endocrinol. Metab. | pmid:10022435 |
Praghakaran K et al. | Rational management of posttransplant lymphoproliferative disorder in pediatric recipients. | 1999 | J. Pediatr. Surg. | pmid:10022154 |
Hersperger R et al. | Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10021934 |