Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Przepiorka D et al. | Tacrolimus for prevention of graft-versus-host disease after mismatched unrelated donor cord blood transplantation. | 1999 | Bone Marrow Transplant. | pmid:10414918 |
Bavetta S et al. | The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration. | 1999 | Exp. Neurol. | pmid:10415144 |
Kuroda S et al. | The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats. | 1999 | Brain Res. | pmid:10415369 |
Finn WF | FK506 nephrotoxicity. | 1999 May-Jul | Ren Fail | pmid:10416209 |
Min DI et al. | Sudden hearing loss associated with tacrolimus in a kidney-pancreas allograft recipient. | 1999 | Pharmacotherapy | pmid:10417040 |
Mrowietz U | Macrolide immunosuppressants. | 1999 Jul-Aug | Eur J Dermatol | pmid:10417434 |
Remitz A et al. | Tacrolimus ointment improves psoriasis in a microplaque assay. | 1999 | Br. J. Dermatol. | pmid:10417522 |
Dalvit C et al. | Use of organic solvents and small molecules for locating binding sites on proteins in solutions. | 1999 | J. Biomol. NMR | pmid:10419292 |
Dunn SE et al. | Calcineurin is required for skeletal muscle hypertrophy. | 1999 | J. Biol. Chem. | pmid:10419511 |
Becker JW et al. | 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. | 1999 | J. Med. Chem. | pmid:10425089 |