tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Moncourier M et al. | [Granulomatous periocular eruption]. | Ann Dermatol Venereol | pmid:28410769 | |
| Kotowski M et al. | The Importance of New Generation Sequencing (NGS) HLA Typing in Renal Transplantation-Preliminary Report. | Transplant. Proc. | pmid:29937294 | |
| pmid:8615615 | ||||
| Mayba JN and Gooderham MJ | Review of Atopic Dermatitis and Topical Therapies. | J Cutan Med Surg | pmid:28300440 | |
| Gupta S and Brennan DC | Pneumococcal 13-Valent Conjugate Vaccine (Prevnar 13)-Associated Immune Thrombocytopenic Purpura in a Renal Transplant Recipient: A Case Report. | Transplant. Proc. | pmid:26915880 | |
| Stringa P et al. | Pretreatment Combination Reduces Remote Organ Damage Secondary to Intestinal Reperfusion Injury in Mice: Follow-up Study. | Transplant. Proc. | pmid:26915870 | |
| Soda M et al. | Association Between Tacrolimus Pharmacokinetics and Cytochrome P450 3A5 and Multidrug Resistance Protein 1 Exon 21 Polymorphisms. | Transplant. Proc. | pmid:28736028 | |
| Mac Guad R et al. | Effects of CYP3A5 Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Renal Transplant Recipients. | Transplant. Proc. | pmid:26915847 | |
| Payabvash S et al. | Cerebellar superficial siderosis of chronic subarachnoid hemorrhage in a patient with Tacrolimus-associated posterior reversible encephalopathy. | J Postgrad Med | pmid:25370549 | |
| Lian Y et al. | Suppression of Delayed Xenograft Rejection by Resveratrol in a Hamster-to-Rat Cardiac Transplantation Model. | Transplant. Proc. | pmid:28736027 | |
| Akoglu H et al. | Relationship between hemorheology and endothelial dysfunction in renal transplant patients receiving calcineurin inhibitors. | J. Nephrol. | pmid:23147686 | |
| Park ES et al. | Renal outcome of kidney-transplantation in Korean recipients with ANCA-associated vasculitis. | Clin. Exp. Rheumatol. | pmid:29185962 | |
| Loredana Asztalos M et al. | Recurrent dermatitis and dermal hypersensitivity following a jellyfish sting: a case report and review of literature. | Pediatr Dermatol | pmid:24495001 | |
| Omland SH and Gniadecki R | Psoriasis inversa: A separate identity or a variant of psoriasis vulgaris? | Clin. Dermatol. | pmid:26051061 | |
| pmid:19200227 | ||||
| Qu W et al. | Correlation Between Immunosuppressive Therapy and CD4(+) T-Cell Intracellular Adenosine Triphosphate Levels in Liver Transplant Recipients. | Transplant. Proc. | pmid:27569951 | |
| Mlinšek G et al. | The role of single nucleotide polymorphisms of CYP3A and ABCB1 on tacrolimus predose concentration in kidney transplant recipients. | Clin. Nephrol. | pmid:28655393 | |
| Bonatti HJR et al. | Clostridium difficile-Associated Colitis Post-Transplant Is Not Associated with Elevation of Tacrolimus Concentrations. | Surg Infect (Larchmt) | pmid:28650734 | |
| Chia BK and Tey HL | Systematic review on the efficacy, safety, and cost-effectiveness of topical calcineurin inhibitors in atopic dermatitis. | Dermatitis | pmid:25984688 | |
| Wei KC and Lai PC | Combination of everolimus and tacrolimus: a potentially effective regimen for recalcitrant psoriasis. | Dermatol Ther | pmid:25285355 | |
| Luger T et al. | Recommendations for pimecrolimus 1% cream in the treatment of mild-to-moderate atopic dermatitis: from medical needs to a new treatment algorithm. | Eur J Dermatol | pmid:24185493 | |
| Park J et al. | Persistent generalized lichen nitidus successfully treated with 0.03% tacrolimus ointment. | Eur J Dermatol | pmid:24184632 | |
| Lentine KL et al. | Variation in Comedication Use According to Kidney Transplant Immunosuppressive Regimens: Application of Integrated Registry and Pharmacy Claims Data. | Transplant. Proc. | pmid:26915843 | |
| Fernández C et al. | Kidney transplantation from HLA-incompatible live donors: Efficiency and outcome of 32 patients after desensitisation. | Nefrologia | pmid:28734583 | |
| Menéndez Valladares P et al. | [Increased lipoprotein(a) in a paediatric patient associated with nephrotic syndrome]. | Clin Investig Arterioscler | pmid:27623226 | |
| Zhao DQ et al. | Sirolimus-Based Immunosuppressive Regimens in Renal Transplantation: A Systemic Review. | Transplant. Proc. | pmid:26915834 | |
| Yang A and Wang B | Sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids: focus on acute rejection, patient and graft survival. | Am J Ther | pmid:23921809 | |
| Liendo VL et al. | Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children. | Arq Bras Oftalmol | pmid:28954018 | |
| Mackesy MM et al. | Immunosuppressant-induced acneiform eruption of the breast. | Breast J | pmid:25229395 | |
| Pan W et al. | Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery. | Int J Nanomedicine | pmid:27578973 | |
| Johnson JL et al. | Pyoderma gangrenosum associated with an aseptic splenic abscess in a patient with neurofibromatosis. | Pediatr Dermatol | pmid:23535023 | |
| Moreno Gonzales M et al. | Sublingual Tacrolimus in Liver Transplantation: A Valid Option? | Transplant. Proc. | pmid:27569953 | |
| Ciancio G et al. | Pilot Randomized Trial of Tacrolimus/Everolimus vs Tacrolimus/Enteric-Coated Mycophenolate Sodium in Adult, Primary Kidney Transplant Recipients at a Single Center. | Transplant. Proc. | pmid:27569936 | |
| pmid:25901935 | ||||
| Yigitaslan S et al. | The Effect of P-Glycoprotein Inhibition and Activation on the Absorption and Serum Levels of Cyclosporine and Tacrolimus in Rats. | Adv Clin Exp Med | pmid:27627555 | |
| Sahu MK et al. | High blood tacrolimus and hyperkalemia in a heart transplant patient. | Ann Card Anaesth | pmid:28393798 | |
| Kathuria S et al. | Segmental vitiligo: a randomized controlled trial to evaluate efficacy and safety of 0.1% tacrolimus ointment vs 0.05% fluticasone propionate cream. | Indian J Dermatol Venereol Leprol | pmid:22199063 | |
| Gómez-Sánchez ME et al. | Intralymphatic Histiocytosis: A Report of 2 Cases. | Actas Dermosifiliogr | pmid:28256202 | |
| López-Oliva MO et al. | Switch to belatacept in kidney graft recipients. | Nefrologia | pmid:28233569 | |
| Jefferson J et al. | Follicular Mucinosis in a Male Adolescent with a History of Acute Myelogenous Leukemia and Graft-versus-Host Disease. | Pediatr Dermatol | pmid:26645410 | |
| Sarvary E et al. | De novo Prograf versus de novo Advagraf: are trough level profile curves similar? | Transplant. Proc. | pmid:25131131 | |
| Borda B et al. | Early histopathological changes in new-onset diabetes after kidney transplantation. | Transplant. Proc. | pmid:25131129 | |
| Porubsky M et al. | Excellent outcomes can be achieved in young pancreas transplant alone recipients by addition of sirolimus to maintenance immunosuppression regimen. | Transplant. Proc. | pmid:25131074 | |
| Lasa J and Olivera P | EFFICACY OF TACROLIMUS FOR INDUCTION OF REMISSION IN PATIENTS WITH MODERATE-TO-SEVERE ULCERATIVE COLITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS. | Arq Gastroenterol | pmid:28327826 | |
| Tulaci KG et al. | The effect of tacrolimus on facial nerve injury: Histopathological findings in a rabbit model. | Am J Otolaryngol | pmid:27465503 | |
| Liu JY et al. | Tacrolimus Versus Cyclosporine as Primary Immunosuppressant After Renal Transplantation: A Meta-Analysis and Economics Evaluation. | Am J Ther | pmid:25299636 | |
| pmid:9123014 | ||||
| Lima RS et al. | Granuloma faciale: a good therapeutic response with the use of topical tacrolimus. | An Bras Dermatol | pmid:26560220 | |
| Alokaily F et al. | Takayasu's arteritis and liver transplantation: Association and implications. | Saudi J Gastroenterol | pmid:26458863 | |
| Haroon N et al. | Tacrolimus Toxicity With Minimal Clinical Manifestations: A Case Report and Literature Review. | Am J Ther | pmid:25730156 | |
| Krzyżowska K et al. | No Significant Influence of Reduced Initial Tacrolimus Dose on Risk of Underdosing and Early Graft Function in Older and Overweight Kidney Transplant Recipients. | Transplant. Proc. | pmid:30056895 | |
| Zmonarski S et al. | Expression of PBMC TLR4 in Renal Graft Recipients Who Experienced Delayed Graft Function Reflects Dynamic Balance Between Blood and Tissue Compartments and Helps Select a Problematic Patient. | Transplant. Proc. | pmid:30056893 | |
| Kubiça TF et al. | Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates. | Braz J Infect Dis | pmid:27697432 | |
| Ming M et al. | Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response. | Photochem. Photobiol. | pmid:25039758 | |
| Zulim LFDC et al. | Comparison of the efficacy of 0.03% tacrolimus eye drops diluted in olive oil and linseed oil for the treatment of keratoconjunctivitis sicca in dogs. | Arq Bras Oftalmol | pmid:29995121 | |
| pmid:9123237 | ||||
| Kim K et al. | Everolimus-Induced Systemic Serositis After Simultaneous Liver and Kidney Transplantation: A Case Report. | Transplant. Proc. | pmid:28104132 | |
| Yamamoto T et al. | Efficacy of Eculizumab Therapy for Atypical Hemolytic Uremic Syndrome Recurrence and Antibody-Mediated Rejection Progress After Renal Transplantation With Preformed Donor-Specific Antibodies: Case Report. | Transplant. Proc. | pmid:28104125 | |
| Dogra PM et al. | Tacrolimus for treatment of toxic epidermal necrolysis. | Indian J Dermatol Venereol Leprol | pmid:26515857 | |
| pmid:11334064 | ||||
| Ülkümen PK et al. | Annular lichenoid dermatitis of youth in a 15-year-old boy: Topical tacrolimus as a treatment option. | Indian J Dermatol Venereol Leprol | pmid:27279324 | |
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| pmid:10773614 | ||||
| Kabuto M et al. | Annular lupus erythematosus profundus. | Eur J Dermatol | pmid:25115404 | |
| Takahashi Y et al. | Pharmacokinetic Profile of Twice- and Once-daily Tacrolimus in Pediatric Kidney Transplant Recipients. | Transplant. Proc. | pmid:28104153 | |
| Shi Y et al. | Comparison of Mizoribine and Mycophenolate Mofetil With a Tacrolimus-Based Immunosuppressive Regimen in Living-Donor Kidney Transplantation Recipients: A Retrospective Study in China. | Transplant. Proc. | pmid:28104150 | |
| Pan D et al. | Tacrolimus-associated Diffuse Gastrointestinal Ulcerations and Pathergy: A Case Report. | Transplant. Proc. | pmid:28104141 | |
| Ash MM and Jolly PS | A Case Report of the Resolution of Multiple Recalcitrant Verrucae in a Renal Transplant Recipient After a Mycophenolate Mofetil Dose Reduction. | Transplant. Proc. | pmid:28104140 | |
| Nayeri A et al. | Acute Calcineurin Inhibitor Nephrotoxicity Secondary to Turmeric Intake: A Case Report. | Transplant. Proc. | pmid:28104136 | |
| Dedhia P et al. | Eculizumab and Belatacept for De Novo Atypical Hemolytic Uremic Syndrome Associated With CFHR3-CFHR1 Deletion in a Kidney Transplant Recipient: A Case Report. | Transplant. Proc. | pmid:28104134 | |
| Zhang J et al. | Chemotherapy for De Novo Gastric Adenocarcinoma After Deceased Orthotopic Liver Transplantation: A Case Report. | Transplant. Proc. | pmid:28104131 | |
| Britto-Williams P and Pansare M | Management of chronic idiopathic urticaria in childhood: are we on the same page? | J Allergy Clin Immunol Pract | pmid:24565627 | |
| Nunokawa T et al. | Late-onset scleroderma renal crisis induced by tacrolimus and prednisolone: a case report. | Am J Ther | pmid:22836123 | |
| Nojima M et al. | Immunosuppression Modification by Everolimus With Minimization of Calcineurin Inhibitors Recovers Kidney Graft Function Even in Patients With Very Late Conversion and Also With Poor Graft Function. | Transplant. Proc. | pmid:28104155 | |
| Ishida S et al. | Calcineurin Inhibitor-Induced Pain Syndrome in ABO-Incompatible Living Kidney Transplantation: A Case Report. | Transplant. Proc. | pmid:28104127 | |
| Forns X et al. | Efficacy of telaprevir-based therapy in stable liver transplant patients with chronic genotype 1 hepatitis C. | Ann Hepatol | pmid:27236150 | |
| pmid:22935463 | ||||
| Ito T et al. | Therapeutic Effect of Sirolimus for Lymphangioleiomyomatosis Remaining in the Abdominopelvic Region After Lung Transplantation: A Case Report. | Transplant. Proc. | pmid:26915883 | |
| Liu JY et al. | Sirolimus Versus Tacrolimus as Primary Immunosuppressant After Renal Transplantation: A Meta-Analysis and Economics Evaluation. | Am J Ther | pmid:25569597 | |
| Norero B et al. | Â Conversion to mycophenolate mofetil monotherapy in liver recipients: Calcineurin inhibitor levels are key. | Ann Hepatol | pmid:28051798 | |
| Hirata Y et al. | Antibody Drug Treatment for Steroid-Resistant Rejection After Pediatric Living Donor Liver Transplantation: A Single-Center Experience. | Transplant. Proc. | pmid:29407332 | |
| Back JH et al. | Antiproteinuric Effects of Green Tea Extract on Tacrolimus-Induced Nephrotoxicity in Mice. | Transplant. Proc. | pmid:26293093 | |
| Shingaki S et al. | Graft-versus-host Disease-free, Relapse-free Survival After HLA-identical Sibling Peripheral Blood Stem Cell Transplantation With Tacrolimus-based Graft-versus-host Disease Prophylaxis in Japanese Patients. | Transplant. Proc. | pmid:29407317 | |
| Kim SH et al. | Outcomes of Early Conversion From Prograf to Generic Tacrolimus in Adult Living Donor Liver Transplant Recipients. | Transplant. Proc. | pmid:26293073 | |
| Manzia TM et al. | Ab initio Everolimus-based Versus Standard Calcineurin Inhibitor Immunosuppression Regimen in Liver Transplant Recipients. | Transplant. Proc. | pmid:29407305 | |
| Falconer SJ et al. | Early or Late Conversion From Tac-BD to Tac-BD in Renal Transplantation: When is the Right Time? | Transplant. Proc. | pmid:26293044 | |
| Clark K et al. | Oxidative Stress Induces Disruption of the Axon Initial Segment. | ASN Neuro | pmid:29228786 | |
| Dall'Agnol DJ et al. | Effects of immunosuppressive drugs on gastrointestinal transit of rats: effects of tacrolimus, cyclosporine, and prednisone. | Transplant. Proc. | pmid:25131057 | |
| Byun JW et al. | A successful helium-neon laser and topical tacrolimus combination therapy in one child with vitiligo. | Dermatol Ther | pmid:26278617 | |
| pmid:28951508 | ||||
| pmid:28761977 | ||||
| Mori F et al. | Increase of natural killer cells in children with liver transplantation-acquired food allergy. | Allergol Immunopathol (Madr) | pmid:29456038 | |
| pmid:28422431 | ||||
| Yousuf Bhat Z et al. | Colchicine-Induced Myopathy in a Tacrolimus-Treated Renal Transplant Recipient: Case Report and Literature Review. | Am J Ther | pmid:24732905 | |
| pmid:11111152 | ||||
| Regueiro-GarcÃa A et al. | Haploidentical stem cell transplantation in a boy with chronic granulomatous disease. | Allergol Immunopathol (Madr) | pmid:29373243 | |
| Lythgoe M and Abraham S | Tacrolimus: an effective treatment in refractory psoriatic arthritis following biologic failure. | Clin. Exp. Rheumatol. | pmid:26211753 | |
| Malik S et al. | Disseminated infection in a kidney-pancreas transplant recipient: A case report and review of the literature. | Saudi J Kidney Dis Transpl | pmid:27900974 | |
| Leon L et al. | Successfull Simultaneous Pancreas Kidney transplantation in a patient with Congenital Partial Lipodystrophy. | Nefrologia | pmid:27006329 | |
| Tan GF et al. | Anogenital epidermolytic acanthomas: effective treatment of pruritus with 0.1% tacrolimus ointment. | Dermatol Ther | pmid:24703270 |