Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yang J et al. | Sjögren's syndrome in mice carrying the Ipr(cg) gene and the therapeutic efficacy of an immunosuppressive agent FK506. | 1999 | Pathol. Int. | pmid:10355966 |
Toung TJ et al. | Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats. | 1999 | Stroke | pmid:10356112 |
Muramatsu K et al. | Limb allotransplantation in rats: combined immunosuppression by FK-506 and 15-deoxyspergualin. | 1999 | J Hand Surg Am | pmid:10357540 |
Cheng HH et al. | Oligomerization state influences the degradation rate of 3-hydroxy-3-methylglutaryl-CoA reductase. | 1999 | J. Biol. Chem. | pmid:10358074 |
Cao S et al. | Long-term outcomes in pediatric liver recipients: comparison between cyclosporin A and tacrolimus. | 1999 | Pediatr Transplant | pmid:10359027 |
Doolabh VB and Mackinnon SE | FK506 accelerates functional recovery following nerve grafting in a rat model. | 1999 | Plast. Reconstr. Surg. | pmid:10359255 |
Johnson KL and Lawen A | Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25. | 1999 | Immunol. Cell Biol. | pmid:10361256 |
Gummert JF et al. | Newer immunosuppressive drugs: a review. | 1999 | J. Am. Soc. Nephrol. | pmid:10361877 |
Kanoh S et al. | Effect of FK506 on ATP-induced intracellular calcium oscillations in cow tracheal epithelium. | 1999 | Am. J. Physiol. | pmid:10362712 |
Jiang H et al. | Tacrolimus versus cyclosporin A: a comparative study on rat renal allograft survival. | 1999 | Transpl. Int. | pmid:10363590 |