Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with tacrolimus
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ormaechea-Pérez N et al. | Superficial granulomatous pyoderma. Report of 2 cases treated with topical tacrolimus. | 2013 | Actas Dermosifiliogr | pmid:23933249 |
de la Torre C | [Alcohol intolerance with facial flushing due to topical pimecrolimus treatment]. | 2008 | Actas Dermosifiliogr | pmid:18501181 |
GarcÃa-Rabasco AE et al. | [Pyoderma gangrenosum associated with hidradenitis suppurativa: a case report and review of the literature]. | 2010 | Actas Dermosifiliogr | pmid:20965015 |
Gómez-Sánchez ME et al. | Intralymphatic Histiocytosis: A Report of 2 Cases. | Actas Dermosifiliogr | pmid:28256202 | |
Turrión-Merino L et al. | A Case Series of 4 Patients With Peristomal Pyoderma Gangrenosum: Review of Risk Factors and Treatment Response. | 2016 | Actas Dermosifiliogr | pmid:26626501 |
Pitarch G and Giner F | Periorbital necrobiosis lipoidica. | 2013 | Actas Dermosifiliogr | pmid:23871211 |
Alomar A | [Role of topical calcineurin inhibitors in dermatology]. | 2008 | Actas Dermosifiliogr | pmid:18346422 |
GarcÃa-Delgado R et al. | Systemic Absorption of Topical Tacrolimus in Metastatic Crohn Disease With Skin Ulcers. | 2016 | Actas Dermosifiliogr | pmid:27372545 |
Suárez-Amor O et al. | [Reticular erythematous mucinosis: partial response to treatment with topical tacrolimus]. | 2010 Jan-Feb | Actas Dermosifiliogr | pmid:20109408 |
Sánchez-Pérez J | [Topical pimecrolimus and tacrolimus and the risk of cancer]. | 2007 | Actas Dermosifiliogr | pmid:17555673 |
Almeida P et al. | [Vitiligo. Treatment of 12 cases with topical tacrolimus]. | 2005 | Actas Dermosifiliogr | pmid:16476357 |
Pérez-López I et al. | Koebner phenomenon in a patient with lichen sclerosus following a jellyfish sting: an exceptional morphology. | 2015 | Actas Dermosifiliogr | pmid:25597413 |
Ojeda T et al. | [Ulcerative lichen planus of the sole treated with tacrolimus, 0.1%]. | 2011 | Actas Dermosifiliogr | pmid:21345398 |
Apalla Z et al. | Psoriatic cheilitis: a report of 2 cases treated successfully with topical tacrolimus and a review of the literature. | 2015 | Actas Dermosifiliogr | pmid:26164836 |
Kobashigawa JA | Advances in immunosuppression for heart transplantation. | 1998 | Adv Card Surg | pmid:9917904 |
Hou S | Pregnancy in renal transplant recipients. | 2013 | Adv Chronic Kidney Dis | pmid:23928390 |
Sethna CB and Gipson DS | Treatment of FSGS in Children. | 2014 | Adv Chronic Kidney Dis | pmid:24602468 |
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Yigitaslan S et al. | The Effect of P-Glycoprotein Inhibition and Activation on the Absorption and Serum Levels of Cyclosporine and Tacrolimus in Rats. | Adv Clin Exp Med | pmid:27627555 | |
Heath M and Raugi GJ | Evidence-based evaluation of immunomodulatory therapy for the cutaneous manifestations of lupus. | 2004 | Adv Dermatol | pmid:15544204 |