tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Brain Diseases D001927 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Endotoxemia D019446 27 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ascites D001201 25 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Cystitis D003556 23 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Cholestasis D002779 23 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Fibrosis D005355 23 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Erythema D004890 22 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Mercader P et al. Treatment of protein contact dermatitis with topical tacrolimus. 2005 Acta Derm. Venereol. pmid:16396818
Campione E et al. Combination of low-dosage cyclosporine and topical pimecrolimus in severe atopic dermatitis with chronic hepatitis B. 2008 Acta Derm. Venereol. pmid:18176762
Bovenschen HJ Novel treatment for cheilitis glandularis. 2009 Acta Derm. Venereol. pmid:19197557
Hamade Y et al. Lichen planus in childhood showing various cutaneous features. 2012 Acta Derm. Venereol. pmid:22101991
Benedix F et al. Response of ulcerated necrobiosis lipoidica to clofazimine. 2009 Acta Derm. Venereol. pmid:19997705
Weisshaar E Successful treatment of genital pruritus using topical immunomodulators as a single therapy in multi-morbid patients. 2008 Acta Derm. Venereol. pmid:18311464
Honda Y et al. Disseminated Mycobacterium mantenii infection with multiple purulent cutaneous lesions. 2015 Acta Derm. Venereol. pmid:25881714
Jensen JM et al. Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right-left arm trial. 2013 Acta Derm. Venereol. pmid:23571785
Larsen CG and Thyssen JP Pustular penile pyoderma gangrenosum successfully treated with topical tacrolimus ointment. 2012 Acta Derm. Venereol. pmid:21681352
Jacobs F et al. New approach in combined therapy of perifolliculitis capitis abscedens et suffodiens. 2011 Acta Derm. Venereol. pmid:21681358
Ambo M Relapsing Kaposi's varicelliform eruption and herpes simplex following facial tacrolimus treatment for atopic dermatitis. 2002 Acta Derm. Venereol. pmid:12353724
Chittock J et al. Comparing the Effect of a Twice-weekly Tacrolimus and Betamethasone Valerate Dose on the Subclinical Epidermal Barrier Defect in Atopic Dermatitis. 2015 Acta Derm. Venereol. pmid:25594610
Mrowietz U et al. An experimental ointment formulation of pimecrolimus is effective in psoriasis without occlusion. 2003 Acta Derm. Venereol. pmid:14609102
Pagliarello C et al. Topical tacrolimus and 50% zinc oxide paste for Hailey-Hailey disease: less is more. 2012 Acta Derm. Venereol. pmid:22293917
Kim TW et al. Proactive treatment of adult facial seborrhoeic dermatitis with 0.1% tacrolimus ointment: randomized, double-blind, vehicle-controlled, multi-centre trial. 2013 Acta Derm. Venereol. pmid:23388687
Yamamoto T and Nishioka K Topical tacrolimus is effective for facial lesions of psoriasis. 2000 Nov-Dec Acta Derm. Venereol. pmid:11243645
Lee HY et al. Oral mucous membrane pemphigoid: complete response to topical tacrolimus. 2011 Acta Derm. Venereol. pmid:21597668
Jedlicková H et al. Granuloma faciale successfully treated with topical tacrolimus: a case report. 2008 Acta Dermatovenerol Alp Pannonica Adriat pmid:18454269
Thaçi D and Salgo R The topical calcineurin inhibitor pimecrolimus in atopic dermatitis: a safety update. 2007 Acta Dermatovenerol Alp Pannonica Adriat pmid:17992459
Vukićević J et al. Unilateral multiple lichen striatus treated with tacrolimus ointment: a case report. 2009 Acta Dermatovenerol Alp Pannonica Adriat pmid:19350187