| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infection | D007239 | 6 associated lipids |
| Abnormalities, Multiple | D000015 | 13 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Bone Diseases | D001847 | 4 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Ulcer | D014456 | 16 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Hemorrhage | D006470 | 15 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Femur Head Necrosis | D005271 | 5 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Eye Diseases | D005128 | 12 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wiebe C et al. | Class II Eplet Mismatch Modulates Tacrolimus Trough Levels Required to Prevent Donor-Specific Antibody Development. | 2017 | J. Am. Soc. Nephrol. | pmid:28729289 |
| Chiramel DM et al. | Topical tacrolimus causing gingival hyperplasia: A case report. | 2017 | Dermatol Ther | pmid:27572623 |
| Choi Y et al. | A pharmacogenomic study on the pharmacokinetics of tacrolimus in healthy subjects using the DMET Plus platform. | 2017 | Pharmacogenomics J. | pmid:26882121 |
| Rummo OO et al. | ADHERE: randomized controlled trial comparing renal function in de novo kidney transplant recipients receiving prolonged-release tacrolimus plus mycophenolate mofetil or sirolimus. | 2017 | Transpl. Int. | pmid:27754567 |
| Hou X et al. | Overexpression of Fibulin-5 attenuates burn-induced inflammation via TRPV1/CGRP pathway. | 2017 | Exp. Cell Res. | pmid:28602628 |
| Tang JT et al. | The pharmacokinetics and pharmacodynamics of mycophenolate mofetil in younger and elderly renal transplant recipients. | 2017 | Br J Clin Pharmacol | pmid:27753146 |
| Kita K and Mano Y | Application of volumetric absorptive microsampling device for quantification of tacrolimus in human blood as a model drug of high blood cell partition. | 2017 | J Pharm Biomed Anal | pmid:28601765 |
| Abongwa C et al. | Successful treatment of tacrolimus-related pure red cell aplasia and autoimmune hemolytic anemia with rituximab in a pediatric cardiac transplant patient. | 2017 | Pediatr Blood Cancer | pmid:28598573 |
| Wu Z et al. | FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients. | 2017 | Eur. J. Clin. Pharmacol. | pmid:27747372 |
| Tamashiro EY et al. | Influence of CYP3A4 and CYP3A5 polymorphisms on tacrolimus and sirolimus exposure in stable kidney transplant recipients. | 2017 | Drug Metab Pers Ther | pmid:28593920 |
| Shahidi M | Thrombosis and von Willebrand Factor. | 2017 | Adv. Exp. Med. Biol. | pmid:27628010 |
| Trasi NS et al. | Evaluation of the Crystallization Tendency of Commercially Available Amorphous Tacrolimus Formulations Exposed to Different Stress Conditions. | 2017 | Pharm. Res. | pmid:28687987 |
| Torres IB et al. | Tacrolimus and mycophenolate regimen and subclinical tubulo-interstitial inflammation in low immunological risk renal transplants. | 2017 | Transpl. Int. | pmid:28667664 |
| Miller AK et al. | Transmission of Donor-Derived Breast Carcinoma as a Recurrent Mass in a Keratolimbal Allograft. | 2017 | Cornea | pmid:28476053 |
| Nakagawa K et al. | Immunosuppressive treatment using tacrolimus promotes pregnancy outcome in infertile women with repeated implantation failures. | 2017 | Am. J. Reprod. Immunol. | pmid:28466977 |
| Mourad G et al. | Incidence of Posttransplantation Diabetes Mellitus in De Novo Kidney Transplant Recipients Receiving Prolonged-Release Tacrolimus-Based Immunosuppression With 2 Different Corticosteroid Minimization Strategies: ADVANCE, A Randomized Controlled Trial. | 2017 | Transplantation | pmid:27547871 |
| Tang J et al. | Application of Machine-Learning Models to Predict Tacrolimus Stable Dose in Renal Transplant Recipients. | 2017 | Sci Rep | pmid:28176850 |
| Ikebe T et al. | Hemophagocytic lymphohistiocytosis following influenza vaccination in a patient with aplastic anemia undergoing allogeneic bone marrow stem cell transplantation. | 2017 | Int. J. Hematol. | pmid:28054244 |
| Jin SE et al. | Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump. | 2017 | J Vis Exp | pmid:28362410 |
| Harada S et al. | Complete remission of angiolymphoid hyperplasia with eosinophilia using topical tacrolimus. | 2017 | Eur J Dermatol | pmid:28007668 |
| Zhang L et al. | Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance. | 2017 | BMC Biotechnol. | pmid:28356086 |
| Zheng X et al. | Effect of FK-506 (tacrolimus) therapy on bone healing of titanium implants: a histometric and biomechanical study in mice. | 2017 | Eur. J. Oral Sci. | pmid:27935130 |
| Bellon H et al. | The Effect of Immunosuppression on Airway Integrity. | 2017 | Transplantation | pmid:28471870 |
| Ferjani H et al. | Beneficial effects of mycophenolate mofetil on cardiotoxicity induced by tacrolimus in wistar rats. | 2017 | Exp. Biol. Med. (Maywood) | pmid:26582055 |
| Monaghan P et al. | The antimalarial action of FK506 and rapamycin: evidence for a direct effect on FK506-binding protein PfFKBP35. | 2017 | Parasitology | pmid:28274284 |
| Solari S et al. | Sublingual tacrolimus administration provides similar drug exposure to per-oral route employing lower doses in liver transplantation: a pilot study. | 2017 | Aliment. Pharmacol. Ther. | pmid:28261844 |
| RodrÃguez-Perálvarez M et al. | Maintenance immunosuppression for adults undergoing liver transplantation: a network meta-analysis. | 2017 | Cochrane Database Syst Rev | pmid:28362060 |
| Cui W et al. | Therapy of tacrolimus combined with corticosteroids in idiopathic membranous nephropathy. | 2017 | Braz. J. Med. Biol. Res. | pmid:28355356 |
| Jackson MF et al. | Osteoclast precursors do not express CD68: results from CD68 promoter-driven RANK transgenic mice. | 2017 | FEBS Lett. | pmid:28173622 |
| Chakfe N | Commentary on "Tacrolimus Eluting Suture Inhibits Neointimal Hyperplasia: An Experimental In Vivo Study in Rats". | 2017 | Eur J Vasc Endovasc Surg | pmid:28169106 |
| Siponen M et al. | Topical tacrolimus, triamcinolone acetonide, and placebo in oral lichen planus: a pilot randomized controlled trial. | 2017 | Oral Dis | pmid:28168769 |
| Vanhove T et al. | Response to: 'Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. | 2017 | Br J Clin Pharmacol | pmid:28168728 |
| Gao L et al. | Low incidence of acute graft-versus-host disease with short-term tacrolimus in haploidentical hematopoietic stem cell transplantation. | 2017 | Leuk. Res. | pmid:28273549 |
| Jessop S et al. | Drugs for discoid lupus erythematosus. | 2017 | Cochrane Database Syst Rev | pmid:28476075 |
| Qiao M et al. | The Natural Course of Atopic Dermatitis and the Association with Asthma. | 2017 | Inflammation | pmid:28063089 |
| Aschauer C et al. | Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis. | 2017 | PLoS ONE | pmid:28060893 |
| Dong Y et al. | Risk Factors, Clinical Features, and Treatment Outcomes of Recurrent Mooren Ulcers in China. | 2017 | Cornea | pmid:28060068 |
| de Oliveira JTP et al. | Variability index of tacrolimus serum levels in pediatric liver transplant recipients younger than 12Â years: Non-adherence or risk of non-adherence? | 2017 | Pediatr Transplant | pmid:29034612 |
| Kim YK et al. | New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients. | 2017 | Drug Des Devel Ther | pmid:29033547 |
| Knops N et al. | Tacrolimus dose requirements in paediatric renal allograft recipients are characterized by a biphasic course determined by age and bone maturation. | 2017 | Br J Clin Pharmacol | pmid:27966227 |
| Komaki Y et al. | Pharmacologic therapies for severe steroid refractory hospitalized ulcerative colitis: A network meta-analysis. | 2017 | J. Gastroenterol. Hepatol. | pmid:27957761 |
| Dutta D et al. | Recruitment of calcineurin to the TCR positively regulates T cell activation. | 2017 | Nat. Immunol. | pmid:27941787 |
| Perez LE et al. | Visilizumab with tacrolimus and methotrexate for GvHD prevention after allogeneic hematopoietic cell transplantation from mismatched unrelated donors. | 2017 | Bone Marrow Transplant. | pmid:27991896 |
| Rivosecchi RM et al. | Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients. | 2017 | Antimicrob. Agents Chemother. | pmid:28674051 |
| Lee SM et al. | Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:28673995 |
| Naicker D et al. | Nationwide conversion to generic tacrolimus in pediatric kidney transplant recipients. | 2017 | Pediatr. Nephrol. | pmid:28660366 |
| Wood LA et al. | New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision. | 2017 | J. Cell Biol. | pmid:28954824 |
| Sigurgeirsson B and Luger T | A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal - author response. | 2017 | Br. J. Dermatol. | pmid:28940181 |
| Qi H et al. | Integration of parallel C-labeling experiments and in silico pathway analysis for enhanced production of ascomycin. | 2017 | Biotechnol. Bioeng. | pmid:27869289 |
| Gatault P et al. | Reduction of Extended-Release Tacrolimus Dose in Low-Immunological-Risk Kidney Transplant Recipients Increases Risk of Rejection and Appearance of Donor-Specific Antibodies: A Randomized Study. | 2017 | Am. J. Transplant. | pmid:27862923 |