tacrolimus
Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
Cross Reference
Introduction
To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with tacrolimus?
tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (2)
- Am. J. Physiol. Renal Physiol. (1)
- Drug Metab. Dispos. (1)
- Others (1)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with tacrolimus
PubChem Associated disorders and diseases
What pathways are associated with tacrolimus
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with tacrolimus?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with tacrolimus?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with tacrolimus?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with tacrolimus?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with tacrolimus?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with tacrolimus
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Krähenbühl S et al. | Serious interaction between mibefradil and tacrolimus. | 1998 | Transplantation | pmid:9808502 |
| Marton MJ et al. | Drug target validation and identification of secondary drug target effects using DNA microarrays. | 1998 | Nat. Med. | pmid:9809554 |
| Walder B et al. | Tacrolimus (FK 506)-induced hemolytic uremic syndrome after heart transplantation. | 1998 | J. Heart Lung Transplant. | pmid:9811409 |
| Bachinger A et al. | [Immunosuppression with tacrolimus (FK 506) and cyclosporin A for preventing graft rejection after liver transplantation. Retrospective evaluation of medical costs based on the FG-O157 Study in 224 patients (Germany)]. | 1998 | Chirurg | pmid:9816454 |
| Shapiro R et al. | A prospective, randomized trial to compare tacrolimus and prednisone with and without mycophenolate mofetil in patients undergoing renal transplantation: first report. | 1998 | J. Urol. | pmid:9817305 |
| Wells WA | Coming full circle. Vertex Pharmaceuticals, Inc. | 1998 | Chem. Biol. | pmid:9818152 |
| Ader JL and Rostaing L | Cyclosporin nephrotoxicity: pathophysiology and comparison with FK-506. | 1998 | Curr. Opin. Nephrol. Hypertens. | pmid:9818201 |
| Perego C et al. | Evidence that SMS 201-995 enhances the immunosuppressive effect of FK506. | 1998 | Int. J. Immunopharmacol. | pmid:9818792 |
| Campo JV et al. | Tacrolimus toxic reaction associated with the use of nefazodone: paroxetine as an alternative agent. | 1998 | Arch. Gen. Psychiatry | pmid:9819077 |
| Igarashi K et al. | A novel indication of the activities of small molecule inhibitors of protein-protein interactions: application of the yeast two-hybrid system. | 1998 | J. Antibiot. | pmid:9820241 |
| Neylan JF et al. | Assessment of the frequency and costs of posttransplantation hospitalizations in patients receiving tacrolimus versus cyclosporine. | 1998 | Am. J. Kidney Dis. | pmid:9820446 |
| Patella V et al. | Endogenous superallergen protein Fv induces IL-4 secretion from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE. | 1998 | J. Immunol. | pmid:9820545 |
| Rossi FM and Blau HM | Recent advances in inducible gene expression systems. | 1998 | Curr. Opin. Biotechnol. | pmid:9821271 |
| Antoni FA et al. | Ca2+/calcineurin-inhibited adenylyl cyclase, highly abundant in forebrain regions, is important for learning and memory. | 1998 | J. Neurosci. | pmid:9822726 |
| Maghrabi K and Bohlega S | Cyclosporine-induced migraine with severe vomiting causing loss of renal graft. | 1998 | Clin Neurol Neurosurg | pmid:9822847 |
| Mitsuhashi H et al. | Sulfite is released by human neutrophils in response to stimulation with lipopolysaccharide. | 1998 | J. Leukoc. Biol. | pmid:9823763 |
| Papatheodoridis GV et al. | Ulcerative colitis has an aggressive course after orthotopic liver transplantation for primary sclerosing cholangitis. | 1998 | Gut | pmid:9824344 |
| Boillot O et al. | Reversal of early acute rejection with increased doses of tacrolimus in liver transplantation: a pilot study. | 1998 | Transplantation | pmid:9825815 |
| Jain AB et al. | Comparative incidence of de novo nonlymphoid malignancies after liver transplantation under tacrolimus using surveillance epidemiologic end result data. | 1998 | Transplantation | pmid:9825817 |
| Franz M et al. | Posttransplant hemolytic uremic syndrome in adult retransplanted kidney graft recipients: advantage of FK506 therapy? | 1998 | Transplantation | pmid:9825827 |