tacrolimus

Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.

Cross Reference

Introduction

To understand associated biological information of tacrolimus, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with tacrolimus?

tacrolimus is suspected in Renal glomerular disease, Candidiasis, Mycoses, PARKINSON DISEASE, LATE-ONSET, Morphologically altered structure, Skin Diseases, Infectious and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with tacrolimus

MeSH term MeSH ID Detail
Tuberous Sclerosis D014402 2 associated lipids
Necrobiosis Lipoidica D009335 2 associated lipids
Angiofibroma D018322 2 associated lipids
Immunoblastic Lymphadenopathy D007119 2 associated lipids
Churg-Strauss Syndrome D015267 2 associated lipids
Mediastinitis D008480 2 associated lipids
Ocular Motility Disorders D015835 2 associated lipids
Oliguria D009846 2 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Fibroadenoma D018226 2 associated lipids
Mucinoses D017520 2 associated lipids
Leprosy, Borderline D015439 3 associated lipids
Castleman Disease D005871 3 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Anus Diseases D001004 3 associated lipids
Kidney Tubular Necrosis, Acute D007683 3 associated lipids
Scleritis D015423 3 associated lipids
Pemphigus, Benign Familial D016506 3 associated lipids
Ileus D045823 3 associated lipids
Anemia, Refractory D000753 3 associated lipids
Wounds, Stab D014951 3 associated lipids
Digestive System Diseases D004066 3 associated lipids
Legionellosis D007876 3 associated lipids
Pityriasis D010915 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Meningococcal Infections D008589 3 associated lipids
Keratosis, Actinic D055623 3 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Glomerulonephritis, Membranoproliferative D015432 3 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Perceptual Disorders D010468 3 associated lipids
Fetal Hypoxia D005311 3 associated lipids
Lichen Planus D008010 3 associated lipids
Toxocariasis D014120 3 associated lipids
Pyoderma Gangrenosum D017511 3 associated lipids
Polyneuropathies D011115 3 associated lipids
Trichomonas Infections D014245 3 associated lipids
Peptic Ulcer Perforation D010439 3 associated lipids
Impetigo D007169 3 associated lipids
Leukoencephalopathies D056784 3 associated lipids
Nervous System Autoimmune Disease, Experimental D020721 3 associated lipids
Epidermolysis Bullosa D004820 3 associated lipids
Paronychia D010304 3 associated lipids
Gingivitis D005891 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Facial Neoplasms D005153 3 associated lipids
Pouchitis D019449 3 associated lipids
Cryptococcosis D003453 3 associated lipids
Osteochondrodysplasias D010009 3 associated lipids
Hemophilia B D002836 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with tacrolimus

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with tacrolimus?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with tacrolimus?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with tacrolimus?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with tacrolimus?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with tacrolimus?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with tacrolimus

Download all related citations
Per page 10 20 50 100 | Total 15051
Authors Title Published Journal PubMed Link
Jha AK et al. Dermoscopy as an evolving tool to assess vitiligo activity. 2018 J. Am. Acad. Dermatol. pmid:29229577
Watanabe N et al. The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study. 2018 Biopharm Drug Dispos pmid:29055041
Altieri M et al. Conversion From Once-Daily Prolonged-Release Tacrolimus to Once-Daily Extended-Release Tacrolimus in Stable Liver Transplant Recipients. 2018 Exp Clin Transplant pmid:28697715
Sakai R et al. Efficacy and safety of multitarget therapy with cyclophosphamide and tacrolimus for lupus nephritis: a prospective, single-arm, single-centre, open label pilot study in Japan. 2018 Lupus pmid:28683654
Almeida-Paulo GN et al. Weight of ABCB1 and POR genes on oral tacrolimus exposure in CYP3A5 nonexpressor pediatric patients with stable kidney transplant. 2018 Pharmacogenomics J. pmid:28094348
Asano T et al. The utility of FDG-PET/CT imaging in the evaluation of multicentric reticulohistiocytosis: A case report. 2018 Medicine (Baltimore) pmid:30113451
Belaiche S et al. Factors associated with the variability of calcineurin inhibitor blood levels in kidney recipients grafted for more than 1 year. 2018 Fundam Clin Pharmacol pmid:29069531
Ding CG et al. Early Immunosuppressive Exposure of Enteric-Coated-Mycophenolate Sodium Plus Tacrolimus Associated with Acute Rejection in Expanded Criteria Donor Kidney Transplantation. 2018 Chin. Med. J. pmid:29786042
Malakasioti G et al. Converting immunosuppression from an oral suspension to a granule formulation of tacrolimus in pediatric renal transplant recipients. 2018 Pediatr Transplant pmid:29767471
Wang DD et al. Population pharmacokinetics of tacrolimus in paediatric systemic lupus erythematosus based on real-world study. 2018 J Clin Pharm Ther pmid:29766530
Krzyżowska K et al. Which Kidney Transplant Recipients Can Benefit from the Initial Tacrolimus Dose Reduction? 2018 Biomed Res Int pmid:29651435
Nakagita K et al. Effect of fluconazole on the pharmacokinetics of everolimus and tacrolimus in a heart transplant recipient: Case report. 2018 Int J Clin Pharmacol Ther pmid:29648533
Takeuchi K et al. Comparison of Safety and Efficacy of Tacrolimus versus Infliximab for Active Ulcerative Colitis. 2018 Dig Dis pmid:29050007
Lloberas N et al. Detection of a rare CYP3A4 variant in a transplant patient characterized by a tacrolimus poor metabolizer phenotype. 2018 Pharmacogenomics pmid:29469606
Brooks EK et al. Evaluation of Multiple Linear Regression-Based Limited Sampling Strategies for Enteric-Coated Mycophenolate Sodium in Adult Kidney Transplant Recipients. 2018 Ther Drug Monit pmid:29461443
Chen X et al. A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus. 2018 Medicine (Baltimore) pmid:29668590
Li A et al. Atopic keratoconjunctivitis: A diagnostic dilemma-a case report. 2018 Medicine (Baltimore) pmid:29668589
Costa D et al. Human cryptosporidiosis in immunodeficient patients in France (2015-2017). 2018 Exp. Parasitol. pmid:30107154
Heppt MV et al. Frontal Fibrosing Alopecia: A Retrospective Analysis of 72 Patients from a German Academic Center. 2018 Facial Plast Surg pmid:29278862
Dheer D et al. Tacrolimus: An updated review on delivering strategies for multifarious diseases. 2018 Eur J Pharm Sci pmid:29277665